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213 results
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Covariate adjustment in randomized controlled trials with dichotomous outcomes increases statistical power and reduces sample size requirements.
Hernández AV, Steyerberg EW, Habbema JD. Hernández AV, et al. J Clin Epidemiol. 2004 May;57(5):454-60. doi: 10.1016/j.jclinepi.2003.09.014. J Clin Epidemiol. 2004. PMID: 15196615
Covariate adjustment increased power in randomized controlled trials: an example in traumatic brain injury.
Turner EL, Perel P, Clayton T, Edwards P, Hernández AV, Roberts I, Shakur H, Steyerberg EW; CRASH trial collaborators. Turner EL, et al. Among authors: hernandez av. J Clin Epidemiol. 2012 May;65(5):474-81. doi: 10.1016/j.jclinepi.2011.08.012. Epub 2011 Dec 9. J Clin Epidemiol. 2012. PMID: 22169080 Free PMC article. Clinical Trial.
A systematic review finds methodological improvements necessary for prognostic models in determining traumatic brain injury outcomes.
Mushkudiani NA, Hukkelhoven CW, Hernández AV, Murray GD, Choi SC, Maas AI, Steyerberg EW. Mushkudiani NA, et al. Among authors: hernandez av. J Clin Epidemiol. 2008 Apr;61(4):331-43. doi: 10.1016/j.jclinepi.2007.06.011. J Clin Epidemiol. 2008. PMID: 18313557 Review.
Predictors of stroke within 30 days in patients with non-ST-segment elevation acute coronary syndromes.
Westerhout CM, Hernández AV, Steyerberg EW, Bueno H, White H, Théroux P, Moliterno DJ, Armstrong PW, Califf RM, Wallentin LC, Simoons ML, Boersma E. Westerhout CM, et al. Among authors: hernandez av. Eur Heart J. 2006 Dec;27(24):2956-61. doi: 10.1093/eurheartj/ehl356. Epub 2006 Nov 8. Eur Heart J. 2006. PMID: 17093039
Effects of platelet glycoprotein IIb/IIIa receptor blockers in non-ST segment elevation acute coronary syndromes: benefit and harm in different age subgroups.
Hernández AV, Westerhout CM, Steyerberg EW, Ioannidis JP, Bueno H, White H, Theroux P, Moliterno DJ, Armstrong PW, Califf RM, Wallentin LC, Simoons ML, Boersma E. Hernández AV, et al. Heart. 2007 Apr;93(4):450-5. doi: 10.1136/hrt.2006.098657. Epub 2006 Oct 25. Heart. 2007. PMID: 17065179 Free PMC article.
Adjustment for strong predictors of outcome in traumatic brain injury trials: 25% reduction in sample size requirements in the IMPACT study.
Hernández AV, Steyerberg EW, Butcher I, Mushkudiani N, Taylor GS, Murray GD, Marmarou A, Choi SC, Lu J, Habbema JD, Maas AI. Hernández AV, et al. J Neurotrauma. 2006 Sep;23(9):1295-303. doi: 10.1089/neu.2006.23.1295. J Neurotrauma. 2006. PMID: 16958582
Subgroup analyses in therapeutic cardiovascular clinical trials: are most of them misleading?
Hernández AV, Boersma E, Murray GD, Habbema JD, Steyerberg EW. Hernández AV, et al. Am Heart J. 2006 Feb;151(2):257-64. doi: 10.1016/j.ahj.2005.04.020. Am Heart J. 2006. PMID: 16442886
Randomized controlled trials with time-to-event outcomes: how much does prespecified covariate adjustment increase power?
Hernández AV, Eijkemans MJ, Steyerberg EW. Hernández AV, et al. Ann Epidemiol. 2006 Jan;16(1):41-8. doi: 10.1016/j.annepidem.2005.09.007. Epub 2005 Nov 7. Ann Epidemiol. 2006. PMID: 16275011
Subgroup analysis and covariate adjustment in randomized clinical trials of traumatic brain injury: a systematic review.
Hernández AV, Steyerberg EW, Taylor GS, Marmarou A, Habbema JD, Maas AI. Hernández AV, et al. Neurosurgery. 2005 Dec;57(6):1244-53; discussion 1244-53. doi: 10.1227/01.neu.0000186039.57548.96. Neurosurgery. 2005. PMID: 16331173 Review.
Managing the resource demands of a large sample size in clinical trials: can you succeed with fewer subjects?
Hernández AV, Steyerberg EW. Hernández AV, et al. Med J Aust. 2003 Apr 7;178(7):356-7; author reply 357-8. Med J Aust. 2003. PMID: 12670287 No abstract available.
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