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87 results
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Context-dependent mutation rates may cause spurious signatures of a fixation bias favoring higher GC-content in humans.
Hernandez RD, Williamson SH, Zhu L, Bustamante CD. Hernandez RD, et al. Mol Biol Evol. 2007 Oct;24(10):2196-202. doi: 10.1093/molbev/msm149. Epub 2007 Jul 26. Mol Biol Evol. 2007. PMID: 17656634
Proportionally more deleterious genetic variation in European than in African populations.
Lohmueller KE, Indap AR, Schmidt S, Boyko AR, Hernandez RD, Hubisz MJ, Sninsky JJ, White TJ, Sunyaev SR, Nielsen R, Clark AG, Bustamante CD. Lohmueller KE, et al. Among authors: hernandez rd. Nature. 2008 Feb 21;451(7181):994-7. doi: 10.1038/nature06611. Nature. 2008. PMID: 18288194 Free PMC article.
Assessing the evolutionary impact of amino acid mutations in the human genome.
Boyko AR, Williamson SH, Indap AR, Degenhardt JD, Hernandez RD, Lohmueller KE, Adams MD, Schmidt S, Sninsky JJ, Sunyaev SR, White TJ, Nielsen R, Clark AG, Bustamante CD. Boyko AR, et al. Among authors: hernandez rd. PLoS Genet. 2008 May 30;4(5):e1000083. doi: 10.1371/journal.pgen.1000083. PLoS Genet. 2008. PMID: 18516229 Free PMC article.
Demographic histories and patterns of linkage disequilibrium in Chinese and Indian rhesus macaques.
Hernandez RD, Hubisz MJ, Wheeler DA, Smith DG, Ferguson B, Rogers J, Nazareth L, Indap A, Bourquin T, McPherson J, Muzny D, Gibbs R, Nielsen R, Bustamante CD. Hernandez RD, et al. Science. 2007 Apr 13;316(5822):240-3. doi: 10.1126/science.1140462. Science. 2007. PMID: 17431170
Natural selection on protein-coding genes in the human genome.
Bustamante CD, Fledel-Alon A, Williamson S, Nielsen R, Hubisz MT, Glanowski S, Tanenbaum DM, White TJ, Sninsky JJ, Hernandez RD, Civello D, Adams MD, Cargill M, Clark AG. Bustamante CD, et al. Among authors: hernandez rd. Nature. 2005 Oct 20;437(7062):1153-7. doi: 10.1038/nature04240. Nature. 2005. PMID: 16237444
Context dependence, ancestral misidentification, and spurious signatures of natural selection.
Hernandez RD, Williamson SH, Bustamante CD. Hernandez RD, et al. Mol Biol Evol. 2007 Aug;24(8):1792-800. doi: 10.1093/molbev/msm108. Epub 2007 Jun 1. Mol Biol Evol. 2007. PMID: 17545186
Detection of heterozygous mutations in the genome of mismatch repair defective diploid yeast using a Bayesian approach.
Zanders S, Ma X, Roychoudhury A, Hernandez RD, Demogines A, Barker B, Gu Z, Bustamante CD, Alani E. Zanders S, et al. Among authors: hernandez rd. Genetics. 2010 Oct;186(2):493-503. doi: 10.1534/genetics.110.120105. Epub 2010 Jul 26. Genetics. 2010. PMID: 20660644 Free PMC article.
Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data.
Gutenkunst RN, Hernandez RD, Williamson SH, Bustamante CD. Gutenkunst RN, et al. Among authors: hernandez rd. PLoS Genet. 2009 Oct;5(10):e1000695. doi: 10.1371/journal.pgen.1000695. Epub 2009 Oct 23. PLoS Genet. 2009. PMID: 19851460 Free PMC article.
A flexible forward simulator for populations subject to selection and demography.
Hernandez RD. Hernandez RD. Bioinformatics. 2008 Dec 1;24(23):2786-7. doi: 10.1093/bioinformatics/btn522. Epub 2008 Oct 7. Bioinformatics. 2008. PMID: 18842601 Free PMC article.
Evolutionary processes acting on candidate cis-regulatory regions in humans inferred from patterns of polymorphism and divergence.
Torgerson DG, Boyko AR, Hernandez RD, Indap A, Hu X, White TJ, Sninsky JJ, Cargill M, Adams MD, Bustamante CD, Clark AG. Torgerson DG, et al. Among authors: hernandez rd. PLoS Genet. 2009 Aug;5(8):e1000592. doi: 10.1371/journal.pgen.1000592. Epub 2009 Aug 7. PLoS Genet. 2009. PMID: 19662163 Free PMC article.
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