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Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.
Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, Lin H, Arking DE, Smith AV, Albert CM, Chaffin M, Tucker NR, Li M, Klarin D, Bihlmeyer NA, Low SK, Weeke PE, Müller-Nurasyid M, Smith JG, Brody JA, Niemeijer MN, Dörr M, Trompet S, Huffman J, Gustafsson S, Schurmann C, Kleber ME, Lyytikäinen LP, Seppälä I, Malik R, Horimoto ARVR, Perez M, Sinisalo J, Aeschbacher S, Thériault S, Yao J, Radmanesh F, Weiss S, Teumer A, Choi SH, Weng LC, Clauss S, Deo R, Rader DJ, Shah SH, Sun A, Hopewell JC, Debette S, Chauhan G, Yang Q, Worrall BB, Paré G, Kamatani Y, Hagemeijer YP, Verweij N, Siland JE, Kubo M, Smith JD, Van Wagoner DR, Bis JC, Perz S, Psaty BM, Ridker PM, Magnani JW, Harris TB, Launer LJ, Shoemaker MB, Padmanabhan S, Haessler J, Bartz TM, Waldenberger M, Lichtner P, Arendt M, Krieger JE, Kähönen M, Risch L, Mansur AJ, Peters A, Smith BH, Lind L, Scott SA, Lu Y, Bottinger EB, Hernesniemi J, Lindgren CM, Wong JA, Huang J, Eskola M, Morris AP, Ford I, Reiner AP, Delgado G, Chen LY, Chen YI, Sandhu RK, Li M, Boerwinkle E, Eisele L, Lannfelt L, Rost N, Anderson CD, Taylor KD, Campbell A, Magnusson PK, Porteous D, Hocking LJ, Vlachopoulou E, Pedersen NL, Niku… See abstract for full author list ➔ Christophersen IE, et al. Among authors: hernesniemi j. Nat Genet. 2017 Jun;49(6):946-952. doi: 10.1038/ng.3843. Epub 2017 Apr 17. Nat Genet. 2017. PMID: 28416818 Free PMC article.
Coronary artery disease-related genetic variant on chromosome 10q11 is associated with carotid intima-media thickness and atherosclerosis.
Kiechl S, Laxton RC, Xiao Q, Hernesniemi JA, Raitakari OT, Kähönen M, Mayosi BM, Jula A, Moilanen L, Willeit J, Watkins H, Samani NJ, Lehtimäki TJ, Keavney B, Xu Q, Ye S. Kiechl S, et al. Among authors: hernesniemi ja. Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2678-83. doi: 10.1161/ATVBAHA.110.213785. Epub 2010 Sep 16. Arterioscler Thromb Vasc Biol. 2010. PMID: 20847302
Genetic variants and their interactions in the prediction of increased pre-clinical carotid atherosclerosis: the cardiovascular risk in young Finns study.
Okser S, Lehtimäki T, Elo LL, Mononen N, Peltonen N, Kähönen M, Juonala M, Fan YM, Hernesniemi JA, Laitinen T, Lyytikäinen LP, Rontu R, Eklund C, Hutri-Kähönen N, Taittonen L, Hurme M, Viikari JS, Raitakari OT, Aittokallio T. Okser S, et al. PLoS Genet. 2010 Sep 30;6(9):e1001146. doi: 10.1371/journal.pgen.1001146. PLoS Genet. 2010. PMID: 20941391 Free PMC article.
Association of apolipoprotein E promoter polymorphisms with bone structural traits is modified by dietary saturated fat intake - the Cardiovascular Risk in Young Finns study.
Tolonen S, Mikkilä V, Laaksonen M, Sievänen H, Mononen N, Hernesniemi J, Vehkalahti K, Viikari J, Raitakari O, Kähönen M, Lehtimäki T. Tolonen S, et al. Among authors: hernesniemi j. Bone. 2011 May 1;48(5):1058-65. doi: 10.1016/j.bone.2011.01.013. Epub 2011 Jan 23. Bone. 2011. PMID: 21266206
Childhood environmental and genetic predictors of adulthood obesity: the cardiovascular risk in young Finns study.
Juonala M, Juhola J, Magnussen CG, Würtz P, Viikari JS, Thomson R, Seppälä I, Hernesniemi J, Kähönen M, Lehtimäki T, Hurme M, Telama R, Mikkilä V, Eklund C, Räsänen L, Hintsanen M, Keltikangas-Järvinen L, Kivimäki M, Raitakari OT. Juonala M, et al. Among authors: hernesniemi j. J Clin Endocrinol Metab. 2011 Sep;96(9):E1542-9. doi: 10.1210/jc.2011-1243. Epub 2011 Jul 21. J Clin Endocrinol Metab. 2011. PMID: 21778217 Free PMC article.
Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta-analysis of three independent studies.
Hernesniemi JA, Seppälä I, Lyytikäinen LP, Mononen N, Oksala N, Hutri-Kähönen N, Juonala M, Taittonen L, Smith EN, Schork NJ, Chen W, Srinivasan SR, Berenson GS, Murray SS, Laitinen T, Jula A, Kettunen J, Ripatti S, Laaksonen R, Viikari J, Kähönen M, Raitakari OT, Lehtimäki T. Hernesniemi JA, et al. PLoS One. 2012;7(1):e28931. doi: 10.1371/journal.pone.0028931. Epub 2012 Jan 25. PLoS One. 2012. PMID: 22295058 Free PMC article.
543 results