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Frequency analysis of tumor-reactive cytotoxic T lymphocytes in peripheral blood of a melanoma patient vaccinated with autologous tumor cells.
Herr W, Wölfel T, Heike M, Meyer zum Büschenfelde KH, Knuth A. Herr W, et al. Cancer Immunol Immunother. 1994 Aug;39(2):93-9. doi: 10.1007/BF01525314. Cancer Immunol Immunother. 1994. PMID: 8044834
HLA-DPB1 mismatch alleles represent powerful leukemia rejection antigens in CD4 T-cell immunotherapy after allogeneic stem-cell transplantation.
Herr W, Eichinger Y, Beshay J, Bloetz A, Vatter S, Mirbeth C, Distler E, Hartwig UF, Thomas S. Herr W, et al. Leukemia. 2017 Feb;31(2):434-445. doi: 10.1038/leu.2016.210. Epub 2016 Aug 1. Leukemia. 2017. PMID: 27479183
Addressing tumour tolerance to improve cancer immunotherapy.
Meyer RG, Herr W. Meyer RG, et al. Eur J Immunol. 2010 Dec;40(12):3302-5. doi: 10.1002/eji.201090067. Eur J Immunol. 2010. PMID: 21110313 No abstract available.
LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Brand A, Singer K, Koehl GE, Kolitzus M, Schoenhammer G, Thiel A, Matos C, Bruss C, Klobuch S, Peter K, Kastenberger M, Bogdan C, Schleicher U, Mackensen A, Ullrich E, Fichtner-Feigl S, Kesselring R, Mack M, Ritter U, Schmid M, Blank C, Dettmer K, Oefner PJ, Hoffmann P, Walenta S, Geissler EK, Pouyssegur J, Villunger A, Steven A, Seliger B, Schreml S, Haferkamp S, Kohl E, Karrer S, Berneburg M, Herr W, Mueller-Klieser W, Renner K, Kreutz M. Brand A, et al. Cell Metab. 2016 Nov 8;24(5):657-671. doi: 10.1016/j.cmet.2016.08.011. Epub 2016 Sep 15. Cell Metab. 2016. PMID: 27641098
Superior antitumor in vitro responses of allogeneic matched sibling compared with autologous patient CD8+ T cells.
Kausche S, Wehler T, Schnürer E, Lennerz V, Brenner W, Melchior S, Gröne M, Nonn M, Strand S, Meyer R, Ranieri E, Huber C, Falk CS, Herr W. Kausche S, et al. Cancer Res. 2006 Dec 1;66(23):11447-54. doi: 10.1158/0008-5472.CAN-06-0998. Cancer Res. 2006. PMID: 17145892
Patient-individualized CD8⁺ cytolytic T-cell therapy effectively combats minimal residual leukemia in immunodeficient mice.
Distler E, Albrecht J, Brunk A, Khan S, Schnürer E, Frey M, Mottok A, Jordán-Garrote AL, Brede C, Beilhack A, Mades A, Tomsitz D, Theobald M, Herr W, Hartwig UF. Distler E, et al. Int J Cancer. 2016 Mar 1;138(5):1256-68. doi: 10.1002/ijc.29854. Epub 2015 Oct 5. Int J Cancer. 2016. PMID: 26376181
Strong and sustained effector function of memory- versus naïve-derived T cells upon T-cell receptor RNA transfer: implications for cellular therapy.
Thomas S, Klobuch S, Besold K, Plachter B, Dörrie J, Schaft N, Theobald M, Herr W. Thomas S, et al. Eur J Immunol. 2012 Dec;42(12):3442-53. doi: 10.1002/eji.201242666. Epub 2012 Oct 1. Eur J Immunol. 2012. PMID: 22930221
Alloreactive and leukemia-reactive T cells are preferentially derived from naive precursors in healthy donors: implications for immunotherapy with memory T cells.
Distler E, Bloetz A, Albrecht J, Asdufan S, Hohberger A, Frey M, Schnürer E, Thomas S, Theobald M, Hartwig UF, Herr W. Distler E, et al. Haematologica. 2011 Jul;96(7):1024-32. doi: 10.3324/haematol.2010.037481. Epub 2011 Apr 12. Haematologica. 2011. PMID: 21486863 Free PMC article.
IL-21-treated naive CD45RA+ CD8+ T cells represent a reliable source for producing leukemia-reactive cytotoxic T lymphocytes with high proliferative potential and early differentiation phenotype.
Albrecht J, Frey M, Teschner D, Carbol A, Theobald M, Herr W, Distler E. Albrecht J, et al. Cancer Immunol Immunother. 2011 Feb;60(2):235-48. doi: 10.1007/s00262-010-0936-8. Epub 2010 Nov 3. Cancer Immunol Immunother. 2011. PMID: 21046101
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