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Inhibition of RAS function through targeting an allosteric regulatory site.
Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, Okur MN, Dementieva I, Sicheri F, Therrien M, Hancock JF, Ikura M, Koide S, O'Bryan JP. Spencer-Smith R, et al. Among authors: herrero garcia e. Nat Chem Biol. 2017 Jan;13(1):62-68. doi: 10.1038/nchembio.2231. Epub 2016 Nov 7. Nat Chem Biol. 2017. PMID: 27820802 Free PMC article.
Silencing Intersectin 1 Slows Orthotopic Neuroblastoma Growth in Mice.
Harris J, Herrero-Garcia E, Russo A, Kajdacsy-Balla A, O'Bryan JP, Chiu B. Harris J, et al. Among authors: herrero garcia e. J Pediatr Hematol Oncol. 2017 Nov;39(8):e413-e418. doi: 10.1097/MPH.0000000000000931. J Pediatr Hematol Oncol. 2017. PMID: 28787396 Free PMC article.
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