Herschlag D - Search Results

1

Metal-ion rescue revisited: biochemical detection of site-bound metal ions important for RNA folding.

Frederiksen JK, Li NS, Das R, Herschlag D, Piccirilli JA. Frederiksen JK, et al. Among authors: herschlag d. RNA. 2012 Jun;18(6):1123-41. doi: 10.1261/rna.028738.111. Epub 2012 Apr 26. RNA. 2012. PMID: 22539523 Free PMC article.

2

RNA catalysis by a group I ribozyme. Developing a model for transition state stabilization.

Cech TR, Herschlag D, Piccirilli JA, Pyle AM. Cech TR, et al. Among authors: herschlag d. J Biol Chem. 1992 Sep 5;267(25):17479-82. J Biol Chem. 1992. PMID: 1381347 Free article. Review. No abstract available.

3

Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom.

Herschlag D, Piccirilli JA, Cech TR. Herschlag D, et al. Biochemistry. 1991 May 21;30(20):4844-54. doi: 10.1021/bi00234a003. Biochemistry. 1991. PMID: 2036355

We now describe pre-steady-state kinetic experiments, with sulfur substituting for the pro-RP (nonbridging) phosphoryl oxygen atom at the site of cleavage, that test aspects of a kinetic model proposed for the ribozyme reaction (Herschlag, D., & Cech, T. R. (199 …

We now describe pre-steady-state kinetic experiments, with sulfur substituting for the pro-RP (nonbridging) phosphoryl oxygen atom at the si …

4

Three metal ions at the active site of the Tetrahymena group I ribozyme.

Shan So, Yoshida A, Sun S, Piccirilli JA, Herschlag D. Shan So, et al. Among authors: herschlag d. Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12299-304. doi: 10.1073/pnas.96.22.12299. Proc Natl Acad Sci U S A. 1999. PMID: 10535916 Free PMC article.

5

The role of the cleavage site 2'-hydroxyl in the Tetrahymena group I ribozyme reaction.

Yoshida A, Shan So, Herschlag D, Piccirilli JA. Yoshida A, et al. Among authors: herschlag d. Chem Biol. 2000 Feb;7(2):85-96. doi: 10.1016/s1074-5521(00)00074-0. Chem Biol. 2000. PMID: 10662698

6

An unconventional origin of metal-ion rescue and inhibition in the Tetrahymena group I ribozyme reaction.

Shan SO, Herschlag D. Shan SO, et al. Among authors: herschlag d. RNA. 2000 Jun;6(6):795-813. doi: 10.1017/s1355838200000649. RNA. 2000. PMID: 10864040 Free PMC article.

7

Defining the catalytic metal ion interactions in the Tetrahymena ribozyme reaction.

Shan S, Kravchuk AV, Piccirilli JA, Herschlag D. Shan S, et al. Among authors: herschlag d. Biochemistry. 2001 May 1;40(17):5161-71. doi: 10.1021/bi002887h. Biochemistry. 2001. PMID: 11318638

8

Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations.

O'Rear JL, Wang S, Feig AL, Beigelman L, Uhlenbeck OC, Herschlag D. O'Rear JL, et al. Among authors: herschlag d. RNA. 2001 Apr;7(4):537-45. doi: 10.1017/s1355838201002461. RNA. 2001. PMID: 11345432 Free PMC article.

9

Dissection of a metal-ion-mediated conformational change in Tetrahymena ribozyme catalysis.

Shan SO, Herschlag D. Shan SO, et al. Among authors: herschlag d. RNA. 2002 Jul;8(7):861-72. doi: 10.1017/s1355838202020216. RNA. 2002. PMID: 12166641 Free PMC article.

10

Exploration of the transition state for tertiary structure formation between an RNA helix and a large structured RNA.

Bartley LE, Zhuang X, Das R, Chu S, Herschlag D. Bartley LE, et al. Among authors: herschlag d. J Mol Biol. 2003 May 16;328(5):1011-26. doi: 10.1016/s0022-2836(03)00272-9. J Mol Biol. 2003. PMID: 12729738 Free article.

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