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Page 1
Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.
Cho MH, McDonald ML, Zhou X, Mattheisen M, Castaldi PJ, Hersh CP, Demeo DL, Sylvia JS, Ziniti J, Laird NM, Lange C, Litonjua AA, Sparrow D, Casaburi R, Barr RG, Regan EA, Make BJ, Hokanson JE, Lutz S, Dudenkov TM, Farzadegan H, Hetmanski JB, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Crapo JD, Silverman EK, Beaty TH; NETT Genetics, ICGN, ECLIPSE and COPDGene Investigators. Cho MH, et al. Lancet Respir Med. 2014 Mar;2(3):214-25. doi: 10.1016/S2213-2600(14)70002-5. Epub 2014 Feb 7. Lancet Respir Med. 2014. PMID: 24621683 Free PMC article.
Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed.
Orchard P, Blackwell TW, Kachuri L, Castaldi PJ, Cho MH, Christenson SA, Durda P, Gabriel S, Hersh CP, Huntsman S, Hwang S, Joehanes R, Johnson M, Li X, Lin H, Liu CT, Liu Y, Mak ACY, Manichaikul AW, Paik DT, Saferali A, Smith JD, Taylor KD, Tracy RP, Wang J, Wang M, Weinstock JS, Weiss J, Wheeler HE, Zhou Y, Zöllner S, Wu JC, Mestroni L, Graw S, Taylor MRG, Ortega VE, Johnson WC, Gan W, Abecasis G, Nickerson DA, Gupta N, Ardlie K, Woodruff PG, Bowler RP, Meyers DA, Reiner A, Kooperberg C, Ziv E, Vasan RS, Larson MG, Cupples LA, Silverman EK, Rich SS, Heard-Costa N, Tang H, Rotter JI, Smith AV, Levy D; NHLBI TOPMed Consortium Multi-Omics Working Group32; NHLBI TOPMed Consortium32§; Aguet F, Scott LJ, Raffield LM, Parker SCJ, Abe N, Almasy L, Ament S, Anugu P, Auer P, Avramopoulos D, Balasubramanian A, Barr RG, Barwick L, Beaty T, Becker D, Becker L, Beitelshees A, Benos T, Bezerra M, Bis J, Brody J, Broeckel U, Broome J, Bunting K, Buth E, Carey V, Carty C, Casaburi R, Chaffin M, Chang C, Chang YC, Chavan S, Chen BJ, Chen WM, Choi SH, Chuang LM, Chung RH, Conomos M, Cornell E, Crandall C, Crapo J, Curtis J, Damcott C, David S, de Las Fuentes L, de Vries P, Deka R, DeMeo D, … See abstract for full author list ➔ Orchard P, et al. Among authors: hersh cp. Science. 2026 Jul 16;393(6808):eadx2989. doi: 10.1126/science.adx2989. Epub 2026 Jul 16. Science. 2026. PMID: 42462027
Single-cell sequencing unveils a profibrotic macrophage and infiltrating monocyte niche in the bronchoalveolar lavage of patients with chronic obstructive pulmonary disease.
V Gerayeli F, Yang CX, Wang CJ, Li X, Liggins JA, Park HY, Schmidt A, Cheung CY, Yang JSW, Guinto E, Mostafavi S, Dang H, Stach TR, Gilchrist CL, Yehia D, Morrow JD, Elhusseini ZW, Vahedi M, Sidhu P, Tuong J, Shaipanich T, Leipsic JA, Hersh CP, Koelwyn GJ, Eddy RL, Milne S, Leung JM, Sin DD. V Gerayeli F, et al. Among authors: hersh cp. Am J Respir Crit Care Med. 2026 Aug 1;212(8):1710-1720. doi: 10.1093/ajrccm/aamag206. Am J Respir Crit Care Med. 2026. PMID: 42153326
Discriminative performance and clinical utility of chronic obstructive pulmonary disease exacerbation categories for predicting future exacerbations.
Bhatt SP, Adibi A, Bodduluri S, Bowler RP, Burgel PR, Castaldi PJ, Hersh CP, Janson C, Maiorino E, Mullerova H, Nakhmani A, Oelsner EC, Silverman EK, Wilson CG, Sadatsafavi M. Bhatt SP, et al. Among authors: hersh cp. Am J Respir Crit Care Med. 2026 Aug 1;212(8):1721-1729. doi: 10.1093/ajrccm/aamag118. Am J Respir Crit Care Med. 2026. PMID: 42085195
Whole Genome Sequence Analysis of Weight Loss in 16 972 Participants With COPD Reveals Novel Risk Loci in DRAIC and RFX3.
Chiles JW 3rd, Rocco A, Srinivasasainagendra V, Rossiter HB, Casaburi R, Thalacker-Mercer A, Wells JM, Wan ES, Silverman EK, Cho MH, Hersh CP, Psaty BM, Gharib SA, Gao Y, O'Connor GT, Lange LA, Rich SS, Manichaikul AW, Barr RG, Ortega VE, Meyers DA, Smith AV, Tiwari HK, McDonald MN. Chiles JW 3rd, et al. Among authors: hersh cp. J Cachexia Sarcopenia Muscle. 2026 Jun;17(3):e70293. doi: 10.1002/jcsm.70293. J Cachexia Sarcopenia Muscle. 2026. PMID: 42026014 Free PMC article.
Z variant heterozygosity in alpha-1 antitrypsin deficiency: disease risk and treatment implications.
Hersh CP, Teckman JH, Strnad P, Hakim A, Carroll TP, Hall IP, Ghosh AJ, Barjaktarevic I, McElvaney NG, Kaserman JE, Lomas DA, Strange C, Drummond MB, Rennard S, Hanna KE, Clark VC, Goldklang MP, Iverson P, Wilson AA. Hersh CP, et al. Orphanet J Rare Dis. 2026 Apr 8;21(1):136. doi: 10.1186/s13023-026-04283-9. Orphanet J Rare Dis. 2026. PMID: 41952152 Free PMC article.
288 results