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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2007 2
2008 1
2012 2
2013 7
2014 2
2015 1
2016 1
2017 2
2018 4
2019 6
2020 1
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25 results
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Page 1
Nanobody-Targeted Photodynamic Therapy Selectively Kills Viral GPCR-Expressing Glioblastoma Cells.
De Groof TWM, Mashayekhi V, Fan TS, Bergkamp ND, Sastre Toraño J, van Senten JR, Heukers R, Smit MJ, Oliveira S. De Groof TWM, et al. Among authors: heukers r. Mol Pharm. 2019 Jul 1;16(7):3145-3156. doi: 10.1021/acs.molpharmaceut.9b00360. Epub 2019 Jun 19. Mol Pharm. 2019. PMID: 31244224 Free PMC article.
Nanobodies: New avenues for imaging, stabilizing and modulating GPCRs.
De Groof TWM, Bobkov V, Heukers R, Smit MJ. De Groof TWM, et al. Among authors: heukers r. Mol Cell Endocrinol. 2019 Mar 15;484:15-24. doi: 10.1016/j.mce.2019.01.021. Epub 2019 Jan 26. Mol Cell Endocrinol. 2019. PMID: 30690070 Free article. Review.
Nanobodies detecting and modulating GPCRs outside in and inside out.
Heukers R, De Groof TWM, Smit MJ. Heukers R, et al. Curr Opin Cell Biol. 2019 Apr;57:115-122. doi: 10.1016/j.ceb.2019.01.003. Epub 2019 Mar 5. Curr Opin Cell Biol. 2019. PMID: 30849632 Review.
The human cytomegalovirus-encoded G protein-coupled receptor UL33 exhibits oncomodulatory properties.
van Senten JR, Bebelman MP, Fan TS, Heukers R, Bergkamp ND, van Gasselt P, Langemeijer EV, Slinger E, Lagerweij T, Rahbar A, Stigter-van Walsum M, Maussang D, Leurs R, Musters RJP, van Dongen GAMS, Söderberg-Nauclér C, Würdinger T, Siderius M, Smit MJ. van Senten JR, et al. Among authors: heukers r. J Biol Chem. 2019 Nov 1;294(44):16297-16308. doi: 10.1074/jbc.RA119.007796. Epub 2019 Sep 13. J Biol Chem. 2019. PMID: 31519750
CXCR4-targeting nanobodies differentially inhibit CXCR4 function and HIV entry.
Van Hout A, Klarenbeek A, Bobkov V, Doijen J, Arimont M, Zhao C, Heukers R, Rimkunas R, de Graaf C, Verrips T, van der Woning B, de Haard H, Rucker JB, Vermeire K, Handel T, Van Loy T, Smit MJ, Schols D. Van Hout A, et al. Among authors: heukers r. Biochem Pharmacol. 2018 Dec;158:402-412. doi: 10.1016/j.bcp.2018.10.015. Epub 2018 Oct 17. Biochem Pharmacol. 2018. PMID: 30342024
The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth.
Heukers R, Fan TS, de Wit RH, van Senten JR, De Groof TWM, Bebelman MP, Lagerweij T, Vieira J, de Munnik SM, Smits-de Vries L, van Offenbeek J, Rahbar A, van Hoorick D, Söderberg-Naucler C, Würdinger T, Leurs R, Siderius M, Vischer HF, Smit MJ. Heukers R, et al. Oncogene. 2018 Jul;37(30):4110-4121. doi: 10.1038/s41388-018-0255-7. Epub 2018 Apr 30. Oncogene. 2018. PMID: 29706656 Free PMC article.
Nanobody-Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4-mediated HIV-entry and induce antibody effector functions.
Bobkov V, Zarca AM, Van Hout A, Arimont M, Doijen J, Bialkowska M, Toffoli E, Klarenbeek A, van der Woning B, van der Vliet HJ, Van Loy T, de Haard H, Schols D, Heukers R, Smit MJ. Bobkov V, et al. Among authors: heukers r. Biochem Pharmacol. 2018 Dec;158:413-424. doi: 10.1016/j.bcp.2018.10.014. Epub 2018 Oct 17. Biochem Pharmacol. 2018. PMID: 30342023 Free article.
Natural Killer Cell Hypo-responsiveness in Chronic Lymphocytic Leukemia can be Circumvented In Vitro by Adequate Activating Signaling.
Hofland T, Endstra S, Gomes CKP, de Boer R, de Weerdt I, Bobkov V, Riedl JA, Heukers R, Smit MJ, Eldering E, Levin MD, Kater AP, Tonino SH. Hofland T, et al. Among authors: heukers r. Hemasphere. 2019 Oct 30;3(6):e308. doi: 10.1097/HS9.0000000000000308. eCollection 2019 Dec. Hemasphere. 2019. PMID: 31976482 Free PMC article.
VHH-Photosensitizer Conjugates for Targeted Photodynamic Therapy of Met-Overexpressing Tumor Cells.
Heukers R, Mashayekhi V, Ramirez-Escudero M, de Haard H, Verrips TC, van Bergen En Henegouwen PMP, Oliveira S. Heukers R, et al. Antibodies (Basel). 2019 Apr 4;8(2):26. doi: 10.3390/antib8020026. Antibodies (Basel). 2019. PMID: 31544832 Free PMC article.
EGFR targeted nanobody-photosensitizer conjugates for photodynamic therapy in a pre-clinical model of head and neck cancer.
van Driel PBAA, Boonstra MC, Slooter MD, Heukers R, Stammes MA, Snoeks TJA, de Bruijn HS, van Diest PJ, Vahrmeijer AL, van Bergen En Henegouwen PMP, van de Velde CJH, Löwik CWGM, Robinson DJ, Oliveira S. van Driel PBAA, et al. Among authors: heukers r. J Control Release. 2016 May 10;229:93-105. doi: 10.1016/j.jconrel.2016.03.014. Epub 2016 Mar 15. J Control Release. 2016. PMID: 26988602 Free article.
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