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Identification and manipulation of tumor associated macrophages in human cancers.
Heusinkveld M, van der Burg SH. Heusinkveld M, et al. J Transl Med. 2011 Dec 16;9:216. doi: 10.1186/1479-5876-9-216. J Transl Med. 2011. PMID: 22176642 Free PMC article. Review.
Chemotherapy alters monocyte differentiation to favor generation of cancer-supporting M2 macrophages in the tumor microenvironment.
Dijkgraaf EM, Heusinkveld M, Tummers B, Vogelpoel LT, Goedemans R, Jha V, Nortier JW, Welters MJ, Kroep JR, van der Burg SH. Dijkgraaf EM, et al. Among authors: heusinkveld m. Cancer Res. 2013 Apr 15;73(8):2480-92. doi: 10.1158/0008-5472.CAN-12-3542. Epub 2013 Feb 22. Cancer Res. 2013. PMID: 23436796
Activation of tumor-promoting type 2 macrophages by EGFR-targeting antibody cetuximab.
Pander J, Heusinkveld M, van der Straaten T, Jordanova ES, Baak-Pablo R, Gelderblom H, Morreau H, van der Burg SH, Guchelaar HJ, van Hall T. Pander J, et al. Among authors: heusinkveld m. Clin Cancer Res. 2011 Sep 1;17(17):5668-73. doi: 10.1158/1078-0432.CCR-11-0239. Epub 2011 Jul 25. Clin Cancer Res. 2011. PMID: 21788356
M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4+ Th1 cells.
Heusinkveld M, de Vos van Steenwijk PJ, Goedemans R, Ramwadhdoebe TH, Gorter A, Welters MJ, van Hall T, van der Burg SH. Heusinkveld M, et al. J Immunol. 2011 Aug 1;187(3):1157-65. doi: 10.4049/jimmunol.1100889. Epub 2011 Jun 27. J Immunol. 2011. PMID: 21709158
An unexpectedly large polyclonal repertoire of HPV-specific T cells is poised for action in patients with cervical cancer.
de Vos van Steenwijk PJ, Heusinkveld M, Ramwadhdoebe TH, Löwik MJ, van der Hulst JM, Goedemans R, Piersma SJ, Kenter GG, van der Burg SH. de Vos van Steenwijk PJ, et al. Among authors: heusinkveld m. Cancer Res. 2010 Apr 1;70(7):2707-17. doi: 10.1158/0008-5472.CAN-09-4299. Epub 2010 Mar 16. Cancer Res. 2010. PMID: 20233872
The detection of circulating human papillomavirus-specific T cells is associated with improved survival of patients with deeply infiltrating tumors.
Heusinkveld M, Welters MJ, van Poelgeest MI, van der Hulst JM, Melief CJ, Fleuren GJ, Kenter GG, van der Burg SH. Heusinkveld M, et al. Int J Cancer. 2011 Jan 15;128(2):379-89. doi: 10.1002/ijc.25361. Epub 2010 Apr 5. Int J Cancer. 2011. PMID: 20473854
Potential use of lymph node-derived HPV-specific T cells for adoptive cell therapy of cervical cancer.
van Poelgeest MI, Visconti VV, Aghai Z, van Ham VJ, Heusinkveld M, Zandvliet ML, Valentijn AR, Goedemans R, van der Minne CE, Verdegaal EM, Trimbos JB, van der Burg SH, Welters MJ. van Poelgeest MI, et al. Among authors: heusinkveld m. Cancer Immunol Immunother. 2016 Dec;65(12):1451-1463. doi: 10.1007/s00262-016-1892-8. Epub 2016 Sep 12. Cancer Immunol Immunother. 2016. PMID: 27619514 Free PMC article.
Systemic and local human papillomavirus 16-specific T-cell immunity in patients with head and neck cancer.
Heusinkveld M, Goedemans R, Briet RJ, Gelderblom H, Nortier JW, Gorter A, Smit VT, Langeveld AP, Jansen JC, van der Burg SH. Heusinkveld M, et al. Int J Cancer. 2012 Jul 15;131(2):E74-85. doi: 10.1002/ijc.26497. Epub 2011 Nov 19. Int J Cancer. 2012. PMID: 22020783
Intradermal delivery of TLR agonists in a human explant skin model: preferential activation of migratory dendritic cells by polyribosinic-polyribocytidylic acid and peptidoglycans.
Oosterhoff D, Heusinkveld M, Lougheed SM, Kosten I, Lindstedt M, Bruijns SC, van Es T, van Kooyk Y, van der Burg SH, de Gruijl TD. Oosterhoff D, et al. Among authors: heusinkveld m. J Immunol. 2013 Apr 1;190(7):3338-45. doi: 10.4049/jimmunol.1200598. Epub 2013 Mar 6. J Immunol. 2013. PMID: 23467931
Influenza-like Illness in Households with Children of Preschool Age.
Mughini-Gras L, Pijnacker R, Enserink R, Heusinkveld M, van der Hoek W, van Pelt W. Mughini-Gras L, et al. Among authors: heusinkveld m. Pediatr Infect Dis J. 2016 Mar;35(3):242-8. doi: 10.1097/INF.0000000000000988. Pediatr Infect Dis J. 2016. PMID: 26646550
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