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A novel series of non-nucleoside inhibitors of inosine 5'-monophosphate dehydrogenase with immunosuppressive activity.
Biochem Pharmacol. 1999 Sep 1;58(5):867-76. doi: 10.1016/s0006-2952(99)00170-7.
Biochem Pharmacol. 1999.
PMID: 10449198
Pharmacological profile of ZD1611, a novel, orally active endothelin ETA receptor antagonist.
Wilson C, Hunt SJ, Tang E, Wright N, Kelly E, Palmer S, Heys C, Mellor S, James R, Bialecki R.
Wilson C, et al.
J Pharmacol Exp Ther. 1999 Sep;290(3):1085-91.
J Pharmacol Exp Ther. 1999.
PMID: 10454481
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New non-peptide endothelin-A receptor antagonists: synthesis, biological properties, and structure-activity relationships of 5-(dimethylamino)-N-pyridyl-,-N-pyrimidinyl-,-N-pyridazinyl-, and -N-pyrazinyl-1-naphthalenesulfonamides.
Bradbury RH, Bath C, Butlin RJ, Dennis M, Heys C, Hunt SJ, James R, Mortlock AA, Sumner NF, Tang EK, Telford B, Whiting E, Wilson C.
Bradbury RH, et al.
J Med Chem. 1997 Mar 14;40(6):996-1004. doi: 10.1021/jm9604585.
J Med Chem. 1997.
PMID: 9083490
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Spectrum of effects detected in the rat functional observational battery following oral administration of non-CNS targeted compounds.
Redfern WS, Strang I, Storey S, Heys C, Barnard C, Lawton K, Hammond TG, Valentin JP.
Redfern WS, et al.
J Pharmacol Toxicol Methods. 2005 Jul-Aug;52(1):77-82. doi: 10.1016/j.vascn.2005.04.005.
J Pharmacol Toxicol Methods. 2005.
PMID: 15936219
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The functional observational battery and modified Irwin test as global neurobehavioral assessments in the rat: Pharmacological validation data and a comparison of methods.
Redfern WS, Dymond A, Strang I, Storey S, Grant C, Marks L, Barnard C, Heys C, Moyser K, Greenwood K, Cobey D, Moore N, Karp NA, Prior H.
Redfern WS, et al.
J Pharmacol Toxicol Methods. 2019 Jul-Aug;98:106591. doi: 10.1016/j.vascn.2019.106591. Epub 2019 May 27.
J Pharmacol Toxicol Methods. 2019.
PMID: 31146025
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