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Page 1
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor.
Nishimura H, Nose M, Hiai H, Minato N, Honjo T. Nishimura H, et al. Among authors: hiai h. Immunity. 1999 Aug;11(2):141-51. doi: 10.1016/s1074-7613(00)80089-8. Immunity. 1999. PMID: 10485649
Introduction of a PD-1 null mutation into the 2C-TCR (anti-H-2Ld) transgenic mice of the H-2(b/d) background resulted in the chronic and systemic graft-versus-host-like disease. Furthermore, CD8+ 2C-TCR+ PD-1(-/-) T cells exhibited markedly augmented proliferation i …
Introduction of a PD-1 null mutation into the 2C-TCR (anti-H-2Ld) transgenic mice of the H-2(b/d) background resulted in the c …
Genetic analysis of Nakano Cataract and its modifier genes in mice.
Narita M, Wang Y, Kita A, Omi N, Yamada Y, Hiai H. Narita M, et al. Among authors: hiai h. Exp Eye Res. 2002 Dec;75(6):745-51. doi: 10.1006/exer.2002.2068. Exp Eye Res. 2002. PMID: 12470976
PD-1 deficiency results in the development of fatal myocarditis in MRL mice.
Wang J, Okazaki IM, Yoshida T, Chikuma S, Kato Y, Nakaki F, Hiai H, Honjo T, Okazaki T. Wang J, et al. Among authors: hiai h. Int Immunol. 2010 Jun;22(6):443-52. doi: 10.1093/intimm/dxq026. Epub 2010 Apr 21. Int Immunol. 2010. PMID: 20410257
Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b-/-Pdcd1-/- mice.
Okazaki T, Otaka Y, Wang J, Hiai H, Takai T, Ravetch JV, Honjo T. Okazaki T, et al. Among authors: hiai h. J Exp Med. 2005 Dec 19;202(12):1643-8. doi: 10.1084/jem.20051984. Epub 2005 Dec 13. J Exp Med. 2005. PMID: 16352741 Free PMC article.
Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice.
Okazaki T, Tanaka Y, Nishio R, Mitsuiye T, Mizoguchi A, Wang J, Ishida M, Hiai H, Matsumori A, Minato N, Honjo T. Okazaki T, et al. Among authors: hiai h. Nat Med. 2003 Dec;9(12):1477-83. doi: 10.1038/nm955. Epub 2003 Nov 2. Nat Med. 2003. PMID: 14595408
Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.
Wang J, Yoshida T, Nakaki F, Hiai H, Okazaki T, Honjo T. Wang J, et al. Among authors: hiai h. Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11823-8. doi: 10.1073/pnas.0505497102. Epub 2005 Aug 8. Proc Natl Acad Sci U S A. 2005. PMID: 16087865 Free PMC article.
Interaction of Helicobacter pylori-induced follicular gastritis and autoimmune gastritis in BALB/c mice with post-thymectomy autoimmune gastritis.
Okazaki K, Ohana M, Oshima C, Uchida K, Nishi T, Iwano M, Fukui T, Kawasaki K, Matsuura M, Asada M, Tamaki H, Hiai H, Chiba T. Okazaki K, et al. Among authors: hiai h. J Gastroenterol. 2003;38(12):1131-7. doi: 10.1007/s00535-003-1219-3. J Gastroenterol. 2003. PMID: 14714249
The aim of this study was to clarify whether or not H. pylori infection interacts with the development of autoimmune gastritis. METHODS: Neonatally thymectomized BALB/c mice with autoimmune gastritis received orally administered H. pylori and were examined histologi …
The aim of this study was to clarify whether or not H. pylori infection interacts with the development of autoimmune gastritis. METHO …
Involvement of myeloid dendritic cells in the development of gastric secondary lymphoid follicles in Helicobacter pylori-infected neonatally thymectomized BALB/c mice.
Nishi T, Okazaki K, Kawasaki K, Fukui T, Tamaki H, Matsuura M, Asada M, Watanabe T, Uchida K, Watanabe N, Nakase H, Ohana M, Hiai H, Chiba T. Nishi T, et al. Among authors: hiai h. Infect Immun. 2003 Apr;71(4):2153-62. doi: 10.1128/iai.71.4.2153-2162.2003. Infect Immun. 2003. PMID: 12654837 Free PMC article.
However, it is still not clear whether antigen-presenting dendritic cells (DCs) in the stomach have a role in the development of secondary follicles in H. pylori-infected nTx mice. ...Myeloid DCs and FDCs might contribute to the development of gastric secondary lymphoid fo …
However, it is still not clear whether antigen-presenting dendritic cells (DCs) in the stomach have a role in the development of secondary f …
A quantitative trait locus in major histocompatibility complex determining latent period of mouse lymphomas.
Kamoto T, Shisa H, Pataer A, Lu L, Yoshida O, Yamada Y, Hiai H. Kamoto T, et al. Among authors: hiai h. Jpn J Cancer Res. 1996 Apr;87(4):401-4. doi: 10.1111/j.1349-7006.1996.tb00236.x. Jpn J Cancer Res. 1996. PMID: 8641972 Free PMC article.
SL/KH strain of mice: a model of spontaneous pre-B-lymphomas.
Shimada MO, Yamada Y, Nakakuki Y, Okamoto K, Fukumoto M, Honjo T, Hiai H. Shimada MO, et al. Among authors: hiai h. Leuk Res. 1993 Jul;17(7):573-8. doi: 10.1016/0145-2126(93)90087-2. Leuk Res. 1993. PMID: 8326739
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