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Ferroptosis as a p53-mediated activity during tumour suppression.
Jiang L, Kon N, Li T, Wang SJ, Su T, Hibshoosh H, Baer R, Gu W. Jiang L, et al. Among authors: hibshoosh h. Nature. 2015 Apr 2;520(7545):57-62. doi: 10.1038/nature14344. Epub 2015 Mar 18. Nature. 2015. PMID: 25799988 Free PMC article.
Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.
Saal LH, Gruvberger-Saal SK, Persson C, Lövgren K, Jumppanen M, Staaf J, Jönsson G, Pires MM, Maurer M, Holm K, Koujak S, Subramaniyam S, Vallon-Christersson J, Olsson H, Su T, Memeo L, Ludwig T, Ethier SP, Krogh M, Szabolcs M, Murty VV, Isola J, Hibshoosh H, Parsons R, Borg A. Saal LH, et al. Among authors: hibshoosh h. Nat Genet. 2008 Jan;40(1):102-7. doi: 10.1038/ng.2007.39. Epub 2007 Dec 9. Nat Genet. 2008. PMID: 18066063 Free PMC article.
p53 Maintains Baseline Expression of Multiple Tumor Suppressor Genes.
Pappas K, Xu J, Zairis S, Resnick-Silverman L, Abate F, Steinbach N, Ozturk S, Saal LH, Su T, Cheung P, Schmidt H, Aaronson S, Hibshoosh H, Manfredi J, Rabadan R, Parsons R. Pappas K, et al. Among authors: hibshoosh h. Mol Cancer Res. 2017 Aug;15(8):1051-1062. doi: 10.1158/1541-7786.MCR-17-0089. Epub 2017 May 8. Mol Cancer Res. 2017. PMID: 28483946 Free PMC article.
3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma.
Maurer M, Su T, Saal LH, Koujak S, Hopkins BD, Barkley CR, Wu J, Nandula S, Dutta B, Xie Y, Chin YR, Kim DI, Ferris JS, Gruvberger-Saal SK, Laakso M, Wang X, Memeo L, Rojtman A, Matos T, Yu JS, Cordon-Cardo C, Isola J, Terry MB, Toker A, Mills GB, Zhao JJ, Murty VV, Hibshoosh H, Parsons R. Maurer M, et al. Among authors: hibshoosh h. Cancer Res. 2009 Aug 1;69(15):6299-306. doi: 10.1158/0008-5472.CAN-09-0820. Epub 2009 Jul 14. Cancer Res. 2009. PMID: 19602588 Free PMC article.
Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.
She QB, Gruvberger-Saal SK, Maurer M, Chen Y, Jumppanen M, Su T, Dendy M, Lau YK, Memeo L, Horlings HM, van de Vijver MJ, Isola J, Hibshoosh H, Rosen N, Parsons R, Saal LH. She QB, et al. Among authors: hibshoosh h. BMC Cancer. 2016 Aug 2;16:587. doi: 10.1186/s12885-016-2609-2. BMC Cancer. 2016. PMID: 27484095 Free PMC article.
193 results