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ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy.
Phelan DG, Anderson DJ, Howden SE, Wong RC, Hickey PF, Pope K, Wilson GR, Pébay A, Davis AM, Petrou S, Elefanty AG, Stanley EG, James PA, Macciocca I, Bahlo M, Cheung MM, Amor DJ, Elliott DA, Lockhart PJ. Phelan DG, et al. Eur Heart J. 2016 Sep 1;37(33):2586-90. doi: 10.1093/eurheartj/ehw160. Epub 2016 Apr 22. Eur Heart J. 2016. PMID: 27106955
Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies.
Bahlo M, Stankovich J, Danoy P, Hickey PF, Taylor BV, Browning SR; Australian and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene); Brown MA, Rubio JP. Bahlo M, et al. Among authors: hickey pf. Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):794-8. doi: 10.1158/1055-9965.EPI-09-0812. Epub 2010 Mar 3. Cancer Epidemiol Biomarkers Prev. 2010. PMID: 20200434
Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing.
Keniry A, Gearing LJ, Jansz N, Liu J, Holik AZ, Hickey PF, Kinkel SA, Moore DL, Breslin K, Chen K, Liu R, Phillips C, Pakusch M, Biben C, Sheridan JM, Kile BT, Carmichael C, Ritchie ME, Hilton DJ, Blewitt ME. Keniry A, et al. Epigenetics Chromatin. 2016 May 18;9:16. doi: 10.1186/s13072-016-0064-6. eCollection 2016. Epigenetics Chromatin. 2016. PMID: 27195021 Free PMC article.
393 results