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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Farmer H, et al. Among authors: hickson i. Nature. 2005 Apr 14;434(7035):917-21. doi: 10.1038/nature03445. Nature. 2005. PMID: 15829967
Isolation of cDNA clones encoding an enzyme from bovine cells that repairs oxidative DNA damage in vitro: homology with bacterial repair enzymes.
Robson CN, Milne AM, Pappin DJ, Hickson ID. Robson CN, et al. Among authors: hickson id. Nucleic Acids Res. 1991 Mar 11;19(5):1087-92. doi: 10.1093/nar/19.5.1087. Nucleic Acids Res. 1991. PMID: 1708495 Free PMC article.
DNA repair in radiation sensitive mutants of mammalian cells: possible involvement of DNA topoisomerases.
Hickson ID, Davies SL, Davies SM, Robson CN. Hickson ID, et al. Int J Radiat Biol. 1990 Oct;58(4):561-8. doi: 10.1080/09553009014551921. Int J Radiat Biol. 1990. PMID: 1976717 Review.
Identification of critical active-site residues in the multifunctional human DNA repair enzyme HAP1.
Barzilay G, Mol CD, Robson CN, Walker LJ, Cunningham RP, Tainer JA, Hickson ID. Barzilay G, et al. Among authors: hickson id. Nat Struct Biol. 1995 Jul;2(7):561-8. doi: 10.1038/nsb0795-561. Nat Struct Biol. 1995. PMID: 7664124
DNA helicase deficiencies associated with cancer predisposition and premature ageing disorders.
Mohaghegh P, Hickson ID. Mohaghegh P, et al. Among authors: hickson id. Hum Mol Genet. 2001 Apr;10(7):741-6. doi: 10.1093/hmg/10.7.741. Hum Mol Genet. 2001. PMID: 11257107 Review.
Cellular responses to DNA damage.
Norbury CJ, Hickson ID. Norbury CJ, et al. Among authors: hickson id. Annu Rev Pharmacol Toxicol. 2001;41:367-401. doi: 10.1146/annurev.pharmtox.41.1.367. Annu Rev Pharmacol Toxicol. 2001. PMID: 11264462 Review.
Involvement of Schizosaccharomyces pombe Srs2 in cellular responses to DNA damage.
Wang SW, Goodwin A, Hickson ID, Norbury CJ. Wang SW, et al. Among authors: hickson id. Nucleic Acids Res. 2001 Jul 15;29(14):2963-72. doi: 10.1093/nar/29.14.2963. Nucleic Acids Res. 2001. PMID: 11452021 Free PMC article.
Caretaker tumour suppressor genes that defend genome integrity.
Levitt NC, Hickson ID. Levitt NC, et al. Among authors: hickson id. Trends Mol Med. 2002 Apr;8(4):179-86. doi: 10.1016/s1471-4914(02)02298-0. Trends Mol Med. 2002. PMID: 11927276 Review.
Inactivation of homologous recombination suppresses defects in topoisomerase III-deficient mutants.
Oakley TJ, Goodwin A, Chakraverty RK, Hickson ID. Oakley TJ, et al. Among authors: hickson id. DNA Repair (Amst). 2002 Jun 21;1(6):463-82. doi: 10.1016/s1568-7864(02)00032-0. DNA Repair (Amst). 2002. PMID: 12509234
RecQ helicases: caretakers of the genome.
Hickson ID. Hickson ID. Nat Rev Cancer. 2003 Mar;3(3):169-78. doi: 10.1038/nrc1012. Nat Rev Cancer. 2003. PMID: 12612652 Review.
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