Hiebert SW - Search Results

1

Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.

Aho ER, Wang J, Gogliotti RD, Howard GC, Phan J, Acharya P, Macdonald JD, Cheng K, Lorey SL, Lu B, Wenzel S, Foshage AM, Alvarado J, Wang F, Shaw JG, Zhao B, Weissmiller AM, Thomas LR, Vakoc CR, Hall MD, Hiebert SW, Liu Q, Stauffer SR, Fesik SW, Tansey WP. Aho ER, et al. Among authors: hiebert sw. Cell Rep. 2019 Mar 12;26(11):2916-2928.e13. doi: 10.1016/j.celrep.2019.02.047. Cell Rep. 2019. PMID: 30865883 Free PMC article.

2

Integrative network analysis identifies key genes and pathways in the progression of hepatitis C virus induced hepatocellular carcinoma.

Zheng S, Tansey WP, Hiebert SW, Zhao Z. Zheng S, et al. Among authors: hiebert sw. BMC Med Genomics. 2011 Aug 8;4:62. doi: 10.1186/1755-8794-4-62. BMC Med Genomics. 2011. PMID: 21824427 Free PMC article.

3

High-Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML.

Zhao Y, Liu Q, Acharya P, Stengel KR, Sheng Q, Zhou X, Kwak H, Fischer MA, Bradner JE, Strickland SA, Mohan SR, Savona MR, Venters BJ, Zhou MM, Lis JT, Hiebert SW. Zhao Y, et al. Among authors: hiebert sw. Cell Rep. 2016 Aug 16;16(7):2003-16. doi: 10.1016/j.celrep.2016.07.032. Epub 2016 Aug 4. Cell Rep. 2016. PMID: 27498870 Free PMC article.

4

Identification of active miRNA promoters from nuclear run-on RNA sequencing.

Liu Q, Wang J, Zhao Y, Li CI, Stengel KR, Acharya P, Johnston G, Hiebert SW, Shyr Y. Liu Q, et al. Among authors: hiebert sw. Nucleic Acids Res. 2017 Jul 27;45(13):e121. doi: 10.1093/nar/gkx318. Nucleic Acids Res. 2017. PMID: 28460090 Free PMC article.

5

Deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B-cell development.

Stengel KR, Barnett KR, Wang J, Liu Q, Hodges E, Hiebert SW, Bhaskara S. Stengel KR, et al. Among authors: hiebert sw. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8608-8613. doi: 10.1073/pnas.1701610114. Epub 2017 Jul 24. Proc Natl Acad Sci U S A. 2017. PMID: 28739911 Free PMC article.

6

Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation.

Wang J, Zhao Y, Zhou X, Hiebert SW, Liu Q, Shyr Y. Wang J, et al. Among authors: hiebert sw. BMC Genomics. 2018 Aug 23;19(1):633. doi: 10.1186/s12864-018-5016-z. BMC Genomics. 2018. PMID: 30139328 Free PMC article.

7

The CDK7 inhibitor THZ1 alters RNA polymerase dynamics at the 5' and 3' ends of genes.

Sampathi S, Acharya P, Zhao Y, Wang J, Stengel KR, Liu Q, Savona MR, Hiebert SW. Sampathi S, et al. Among authors: hiebert sw. Nucleic Acids Res. 2019 May 7;47(8):3921-3936. doi: 10.1093/nar/gkz127. Nucleic Acids Res. 2019. PMID: 30805632 Free PMC article.

8

Histone deacetylase 3 controls a transcriptional network required for B cell maturation.

Stengel KR, Bhaskara S, Wang J, Liu Q, Ellis JD, Sampathi S, Hiebert SW. Stengel KR, et al. Among authors: hiebert sw. Nucleic Acids Res. 2019 Nov 18;47(20):10612-10627. doi: 10.1093/nar/gkz816. Nucleic Acids Res. 2019. PMID: 31586401 Free PMC article.

9

Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia.

Johnston G, Ramsey HE, Liu Q, Wang J, Stengel KR, Sampathi S, Acharya P, Arrate M, Stubbs MC, Burn T, Savona MR, Hiebert SW. Johnston G, et al. Among authors: hiebert sw. Gene. 2020 Aug 20;752:144758. doi: 10.1016/j.gene.2020.144758. Epub 2020 May 15. Gene. 2020. PMID: 32422235 Free PMC article.

10

PAX3-FOXO1 coordinates enhancer architecture, eRNA transcription, and RNA polymerase pause release at select gene targets.

Zhang S, Wang J, Liu Q, McDonald WH, Bomber ML, Layden HM, Ellis J, Borinstein SC, Hiebert SW, Stengel KR. Zhang S, et al. Among authors: hiebert sw. Mol Cell. 2022 Dec 1;82(23):4428-4442.e7. doi: 10.1016/j.molcel.2022.10.025. Epub 2022 Nov 16. Mol Cell. 2022. PMID: 36395771 Free PMC article.

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