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Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery.
Hieronymus H, Silver PA. Hieronymus H, et al. Nat Genet. 2003 Feb;33(2):155-61. doi: 10.1038/ng1080. Epub 2003 Jan 13. Nat Genet. 2003. PMID: 12524544
Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization.
Casolari JM, Brown CR, Komili S, West J, Hieronymus H, Silver PA. Casolari JM, et al. Among authors: hieronymus h. Cell. 2004 May 14;117(4):427-39. doi: 10.1016/s0092-8674(04)00448-9. Cell. 2004. PMID: 15137937
Genome-wide mRNA surveillance is coupled to mRNA export.
Hieronymus H, Yu MC, Silver PA. Hieronymus H, et al. Genes Dev. 2004 Nov 1;18(21):2652-62. doi: 10.1101/gad.1241204. Epub 2004 Oct 15. Genes Dev. 2004. PMID: 15489286 Free PMC article.
A systems view of mRNP biology.
Hieronymus H, Silver PA. Hieronymus H, et al. Genes Dev. 2004 Dec 1;18(23):2845-60. doi: 10.1101/gad.1256904. Genes Dev. 2004. PMID: 15574591 Review.
Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy.
Du J, Bernasconi P, Clauser KR, Mani DR, Finn SP, Beroukhim R, Burns M, Julian B, Peng XP, Hieronymus H, Maglathlin RL, Lewis TA, Liau LM, Nghiemphu P, Mellinghoff IK, Louis DN, Loda M, Carr SA, Kung AL, Golub TR. Du J, et al. Among authors: hieronymus h. Nat Biotechnol. 2009 Jan;27(1):77-83. doi: 10.1038/nbt.1513. Epub 2008 Dec 21. Nat Biotechnol. 2009. PMID: 19098899 Free PMC article.
Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis.
King JC, Xu J, Wongvipat J, Hieronymus H, Carver BS, Leung DH, Taylor BS, Sander C, Cardiff RD, Couto SS, Gerald WL, Sawyers CL. King JC, et al. Among authors: hieronymus h. Nat Genet. 2009 May;41(5):524-6. doi: 10.1038/ng.371. Epub 2009 Apr 26. Nat Genet. 2009. PMID: 19396167 Free PMC article.
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA, Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM, Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA. Johannessen CM, et al. Among authors: hieronymus h. Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627. Epub 2010 Nov 24. Nature. 2010. PMID: 21107320 Free PMC article.
A public genome-scale lentiviral expression library of human ORFs.
Yang X, Boehm JS, Yang X, Salehi-Ashtiani K, Hao T, Shen Y, Lubonja R, Thomas SR, Alkan O, Bhimdi T, Green TM, Johannessen CM, Silver SJ, Nguyen C, Murray RR, Hieronymus H, Balcha D, Fan C, Lin C, Ghamsari L, Vidal M, Hahn WC, Hill DE, Root DE. Yang X, et al. Among authors: hieronymus h. Nat Methods. 2011 Jun 26;8(8):659-61. doi: 10.1038/nmeth.1638. Nat Methods. 2011. PMID: 21706014 Free PMC article.
Traversing the genomic landscape of prostate cancer from diagnosis to death.
Hieronymus H, Sawyers CL. Hieronymus H, et al. Nat Genet. 2012 May 29;44(6):613-4. doi: 10.1038/ng.2301. Nat Genet. 2012. PMID: 22641202
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.
Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, Wrobel MJ, Lerner J, Brunet JP, Subramanian A, Ross KN, Reich M, Hieronymus H, Wei G, Armstrong SA, Haggarty SJ, Clemons PA, Wei R, Carr SA, Lander ES, Golub TR. Lamb J, et al. Among authors: hieronymus h. Science. 2006 Sep 29;313(5795):1929-35. doi: 10.1126/science.1132939. Science. 2006. PMID: 17008526
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