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Targeting of NPC1 to late endosomes involves multiple signals, including one residing within the putative sterol-sensing domain.
Scott C, Higgins ME, Davies JP, Ioannou YA. Scott C, et al. Among authors: higgins me. J Biol Chem. 2004 Nov 12;279(46):48214-23. doi: 10.1074/jbc.M406090200. Epub 2004 Sep 3. J Biol Chem. 2004. PMID: 15347664 Free article.
Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis.
Carstea ED, Morris JA, Coleman KG, Loftus SK, Zhang D, Cummings C, Gu J, Rosenfeld MA, Pavan WJ, Krizman DB, Nagle J, Polymeropoulos MH, Sturley SL, Ioannou YA, Higgins ME, Comly M, Cooney A, Brown A, Kaneski CR, Blanchette-Mackie EJ, Dwyer NK, Neufeld EB, Chang TY, Liscum L, Strauss JF 3rd, Ohno K, Zeigler M, Carmi R, Sokol J, Markie D, O'Neill RR, van Diggelen OP, Elleder M, Patterson MC, Brady RO, Vanier MT, Pentchev PG, Tagle DA. Carstea ED, et al. Science. 1997 Jul 11;277(5323):228-31. doi: 10.1126/science.277.5323.228. Science. 1997. PMID: 9211849
ADCY9 (Adenylate Cyclase Type 9) Inactivation Protects From Atherosclerosis Only in the Absence of CETP (Cholesteryl Ester Transfer Protein).
Rautureau Y, Deschambault V, Higgins MÈ, Rivas D, Mecteau M, Geoffroy P, Miquel G, Uy K, Sanchez R, Lavoie V, Brand G, Nault A, Williams PM, Suarez ML, Merlet N, Lapointe L, Duquette N, Gillis MA, Samami S, Mayer G, Pouliot P, Raignault A, Maafi F, Brodeur MR, Levesque S, Guertin MC, Dubé MP, Thorin É, Rhainds D, Rhéaume É, Tardif JC. Rautureau Y, et al. Among authors: higgins me. Circulation. 2018 Oct 16;138(16):1677-1692. doi: 10.1161/CIRCULATIONAHA.117.031134. Circulation. 2018. PMID: 29674325
A multi-target antisense approach against PDE4 and PDE7 reduces smoke-induced lung inflammation in mice.
Fortin M, D'Anjou H, Higgins ME, Gougeon J, Aubé P, Moktefi K, Mouissi S, Séguin S, Séguin R, Renzi PM, Paquet L, Ferrari N. Fortin M, et al. Among authors: higgins me. Respir Res. 2009 May 20;10(1):39. doi: 10.1186/1465-9921-10-39. Respir Res. 2009. PMID: 19457265 Free PMC article.
Type III acetabular defect revision with bilobed components: five-year results.
Moskal JT, Higgins ME, Shen J. Moskal JT, et al. Among authors: higgins me. Clin Orthop Relat Res. 2008 Mar;466(3):691-5. doi: 10.1007/s11999-007-0079-1. Epub 2008 Feb 10. Clin Orthop Relat Res. 2008. PMID: 18264858 Free PMC article.
CancerGenes: a gene selection resource for cancer genome projects.
Higgins ME, Claremont M, Major JE, Sander C, Lash AE. Higgins ME, et al. Nucleic Acids Res. 2007 Jan;35(Database issue):D721-6. doi: 10.1093/nar/gkl811. Epub 2006 Nov 6. Nucleic Acids Res. 2007. PMID: 17088289 Free PMC article.
Effects of antisense oligodeoxynucleotides targeting CCR3 on the airway response to antigen in rats.
Fortin M, Ferrari N, Higgins ME, Séguin S, Allam M, Allakhverdi Z, Piaget-Rodriguez C, Paquet L, Renzi PM. Fortin M, et al. Among authors: higgins me. Oligonucleotides. 2006 Fall;16(3):203-12. doi: 10.1089/oli.2006.16.203. Oligonucleotides. 2006. PMID: 16978084
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