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Placental growth retardation due to loss of imprinting of Phlda2.
Salas M, John R, Saxena A, Barton S, Frank D, Fitzpatrick G, Higgins MJ, Tycko B. Salas M, et al. Mech Dev. 2004 Oct;121(10):1199-210. doi: 10.1016/j.mod.2004.05.017. Mech Dev. 2004. PMID: 15327781
Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1.
Fitzpatrick GV, Pugacheva EM, Shin JY, Abdullaev Z, Yang Y, Khatod K, Lobanenkov VV, Higgins MJ. Fitzpatrick GV, et al. Mol Cell Biol. 2007 Apr;27(7):2636-47. doi: 10.1128/MCB.02036-06. Epub 2007 Jan 22. Mol Cell Biol. 2007. PMID: 17242189 Free PMC article.
Identification of DNA methylation in 3' genomic regions that are associated with upregulation of gene expression in colorectal cancer.
Smith JF, Mahmood S, Song F, Morrow A, Smiraglia D, Zhang X, Rajput A, Higgins MJ, Krumm A, Petrelli NJ, Costello JF, Nagase H, Plass C, Held WA. Smith JF, et al. Epigenetics. 2007 Sep;2(3):161-72. doi: 10.4161/epi.2.3.4805. Epub 2007 Jul 27. Epigenetics. 2007. PMID: 17965620
Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7.
Oh R, Ho R, Mar L, Gertsenstein M, Paderova J, Hsien J, Squire JA, Higgins MJ, Nagy A, Lefebvre L. Oh R, et al. Mol Cell Biol. 2008 Feb;28(3):1092-103. doi: 10.1128/MCB.01019-07. Epub 2007 Nov 26. Mol Cell Biol. 2008. PMID: 18039841 Free PMC article.
Two distinct mechanisms of silencing by the KvDMR1 imprinting control region.
Shin JY, Fitzpatrick GV, Higgins MJ. Shin JY, et al. EMBO J. 2008 Jan 9;27(1):168-78. doi: 10.1038/sj.emboj.7601960. Epub 2007 Dec 13. EMBO J. 2008. PMID: 18079696 Free PMC article.
Autonomous silencing of the imprinted Cdkn1c gene in stem cells.
Wood MD, Hiura H, Tunster SJ, Arima T, Shin JY, Higgins MJ, John RM. Wood MD, et al. Epigenetics. 2010 Apr;5(3):214-21. doi: 10.4161/epi.5.3.11275. Epub 2010 Apr 1. Epigenetics. 2010. PMID: 20372090 Free PMC article.
Rescue of placental phenotype in a mechanistic model of Beckwith-Wiedemann syndrome.
Oh-McGinnis R, Bogutz AB, Lee KY, Higgins MJ, Lefebvre L. Oh-McGinnis R, et al. BMC Dev Biol. 2010 May 11;10:50. doi: 10.1186/1471-213X-10-50. BMC Dev Biol. 2010. PMID: 20459838 Free PMC article.
Maternal gametic transmission of translocations or inversions of human chromosome 11p15.5 results in regional DNA hypermethylation and downregulation of CDKN1C expression.
Smith AC, Suzuki M, Thompson R, Choufani S, Higgins MJ, Chiu IW, Squire JA, Greally JM, Weksberg R. Smith AC, et al. Genomics. 2012 Jan;99(1):25-35. doi: 10.1016/j.ygeno.2011.10.007. Epub 2011 Nov 3. Genomics. 2012. PMID: 22079941 Free PMC article.
IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data.
Wang D, Yan L, Hu Q, Sucheston LE, Higgins MJ, Ambrosone CB, Johnson CS, Smiraglia DJ, Liu S. Wang D, et al. Bioinformatics. 2012 Mar 1;28(5):729-30. doi: 10.1093/bioinformatics/bts013. Epub 2012 Jan 16. Bioinformatics. 2012. PMID: 22253290 Free PMC article.
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