Higgins MK - Search Results

1

Severe malaria is associated with parasite binding to endothelial protein C receptor.

Turner L, Lavstsen T, Berger SS, Wang CW, Petersen JE, Avril M, Brazier AJ, Freeth J, Jespersen JS, Nielsen MA, Magistrado P, Lusingu J, Smith JD, Higgins MK, Theander TG. Turner L, et al. Among authors: higgins mk. Nature. 2013 Jun 27;498(7455):502-5. doi: 10.1038/nature12216. Epub 2013 Jun 5. Nature. 2013. PMID: 23739325 Free PMC article.

2

Full-length recombinant Plasmodium falciparum VAR2CSA binds specifically to CSPG and induces potent parasite adhesion-blocking antibodies.

Khunrae P, Dahlbäck M, Nielsen MA, Andersen G, Ditlev SB, Resende M, Pinto VV, Theander TG, Higgins MK, Salanti A. Khunrae P, et al. Among authors: higgins mk. J Mol Biol. 2010 Apr 2;397(3):826-34. doi: 10.1016/j.jmb.2010.01.040. Epub 2010 Jan 25. J Mol Biol. 2010. PMID: 20109466 Free PMC article.

3

Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants.

Barfod L, Dobrilovic T, Magistrado P, Khunrae P, Viwami F, Bruun J, Dahlbäck M, Bernasconi NL, Fried M, John D, Duffy PE, Salanti A, Lanzavecchia A, Lim CT, Ndam NT, Higgins MK, Hviid L. Barfod L, et al. Among authors: higgins mk. J Immunol. 2010 Dec 15;185(12):7553-61. doi: 10.4049/jimmunol.1002390. Epub 2010 Nov 15. J Immunol. 2010. PMID: 21078904 Free PMC article.

4

A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies.

Bengtsson A, Joergensen L, Rask TS, Olsen RW, Andersen MA, Turner L, Theander TG, Hviid L, Higgins MK, Craig A, Brown A, Jensen AT. Bengtsson A, et al. Among authors: higgins mk. J Immunol. 2013 Jan 1;190(1):240-9. doi: 10.4049/jimmunol.1202578. Epub 2012 Dec 3. J Immunol. 2013. PMID: 23209327 Free PMC article.

5

Molecular architecture of a complex between an adhesion protein from the malaria parasite and intracellular adhesion molecule 1.

Brown A, Turner L, Christoffersen S, Andrews KA, Szestak T, Zhao Y, Larsen S, Craig AG, Higgins MK. Brown A, et al. Among authors: higgins mk. J Biol Chem. 2013 Feb 22;288(8):5992-6003. doi: 10.1074/jbc.M112.416347. Epub 2013 Jan 6. J Biol Chem. 2013. PMID: 23297413 Free PMC article.

6

Malaria's deadly grip: cytoadhesion of Plasmodium falciparum-infected erythrocytes.

Smith JD, Rowe JA, Higgins MK, Lavstsen T. Smith JD, et al. Among authors: higgins mk. Cell Microbiol. 2013 Dec;15(12):1976-83. doi: 10.1111/cmi.12183. Epub 2013 Sep 4. Cell Microbiol. 2013. PMID: 23957661 Free PMC article. Review.

7

Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.

Wright KE, Hjerrild KA, Bartlett J, Douglas AD, Jin J, Brown RE, Illingworth JJ, Ashfield R, Clemmensen SB, de Jongh WA, Draper SJ, Higgins MK. Wright KE, et al. Among authors: higgins mk. Nature. 2014 Nov 20;515(7527):427-30. doi: 10.1038/nature13715. Epub 2014 Aug 17. Nature. 2014. PMID: 25132548 Free PMC article.

8

Structural conservation despite huge sequence diversity allows EPCR binding by the PfEMP1 family implicated in severe childhood malaria.

Lau CK, Turner L, Jespersen JS, Lowe ED, Petersen B, Wang CW, Petersen JE, Lusingu J, Theander TG, Lavstsen T, Higgins MK. Lau CK, et al. Among authors: higgins mk. Cell Host Microbe. 2015 Jan 14;17(1):118-29. doi: 10.1016/j.chom.2014.11.007. Epub 2014 Dec 4. Cell Host Microbe. 2015. PMID: 25482433 Free PMC article.

9

Mapping the Binding Site of a Cross-Reactive Plasmodium falciparum PfEMP1 Monoclonal Antibody Inhibitory of ICAM-1 Binding.

Lennartz F, Bengtsson A, Olsen RW, Joergensen L, Brown A, Remy L, Man P, Forest E, Barfod LK, Adams Y, Higgins MK, Jensen AT. Lennartz F, et al. Among authors: higgins mk. J Immunol. 2015 Oct 1;195(7):3273-83. doi: 10.4049/jimmunol.1501404. Epub 2015 Aug 28. J Immunol. 2015. PMID: 26320251 Free PMC article.

10

The structural basis for CD36 binding by the malaria parasite.

Hsieh FL, Turner L, Bolla JR, Robinson CV, Lavstsen T, Higgins MK. Hsieh FL, et al. Among authors: higgins mk. Nat Commun. 2016 Sep 26;7:12837. doi: 10.1038/ncomms12837. Nat Commun. 2016. PMID: 27667267 Free PMC article.

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