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Under DNA stress, gyrase makes the sign of the cross.
Higgins NP. Higgins NP. Nat Struct Mol Biol. 2007 Apr;14(4):256-8. doi: 10.1038/nsmb0407-256. Nat Struct Mol Biol. 2007. PMID: 17410088 No abstract available.
DNA topology of highly transcribed operons in Salmonella enterica serovar Typhimurium.
Booker BM, Deng S, Higgins NP. Booker BM, et al. Among authors: higgins np. Mol Microbiol. 2010 Dec;78(6):1348-64. doi: 10.1111/j.1365-2958.2010.07394.x. Epub 2010 Sep 30. Mol Microbiol. 2010. PMID: 21143310 Free article.
Organization of supercoil domains and their reorganization by transcription.
Deng S, Stein RA, Higgins NP. Deng S, et al. Among authors: higgins np. Mol Microbiol. 2005 Sep;57(6):1511-21. doi: 10.1111/j.1365-2958.2005.04796.x. Mol Microbiol. 2005. PMID: 16135220 Free PMC article. Review.
Structure and activities of Escherichia coli DNA gyrase.
Peebles CL, Higgins NP, Kreuzer KN, Morrison A, Brown PO, Sugino A, Cozzarelli NR. Peebles CL, et al. Among authors: higgins np. Cold Spring Harb Symp Quant Biol. 1979;43 Pt 1:41-52. doi: 10.1101/sqb.1979.043.01.008. Cold Spring Harb Symp Quant Biol. 1979. PMID: 225110 No abstract available.
Topological Behavior of Plasmid DNA.
Higgins NP, Vologodskii AV. Higgins NP, et al. Microbiol Spectr. 2015 Apr;3(2):10.1128/microbiolspec.PLAS-0036-2014. doi: 10.1128/microbiolspec.PLAS-0036-2014. Microbiol Spectr. 2015. PMID: 26104708 Free PMC article. Review.
RNA polymerase: chromosome domain boundary maker and regulator of supercoil density.
Higgins NP. Higgins NP. Curr Opin Microbiol. 2014 Dec;22:138-43. doi: 10.1016/j.mib.2014.10.002. Curr Opin Microbiol. 2014. PMID: 25460807 Free PMC article. Review.
Rates of gyrase supercoiling and transcription elongation control supercoil density in a bacterial chromosome.
Rovinskiy N, Agbleke AA, Chesnokova O, Pang Z, Higgins NP. Rovinskiy N, et al. Among authors: higgins np. PLoS Genet. 2012;8(8):e1002845. doi: 10.1371/journal.pgen.1002845. Epub 2012 Aug 16. PLoS Genet. 2012. PMID: 22916023 Free PMC article.
Microarray analysis of Mu transposition in Salmonella enterica, serovar Typhimurium: transposon exclusion by high-density DNA binding proteins.
Manna D, Porwollik S, McClelland M, Tan R, Higgins NP. Manna D, et al. Among authors: higgins np. Mol Microbiol. 2007 Oct;66(2):315-28. doi: 10.1111/j.1365-2958.2007.05915.x. Epub 2007 Sep 10. Mol Microbiol. 2007. PMID: 17850262 Free article.
Growth rate toxicity phenotypes and homeostatic supercoil control differentiate Escherichia coli from Salmonella enterica serovar Typhimurium.
Champion K, Higgins NP. Champion K, et al. Among authors: higgins np. J Bacteriol. 2007 Aug;189(16):5839-49. doi: 10.1128/JB.00083-07. Epub 2007 Mar 30. J Bacteriol. 2007. PMID: 17400739 Free PMC article.
Mutational bias suggests that replication termination occurs near the dif site, not at Ter sites: what's the Dif?
Higgins NP. Higgins NP. Mol Microbiol. 2007 Apr;64(1):1-4. doi: 10.1111/j.1365-2958.2007.05641.x. Mol Microbiol. 2007. PMID: 17376066 Review.
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