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Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts.
Hansen BJ, Zhao J, Csepe TA, Moore BT, Li N, Jayne LA, Kalyanasundaram A, Lim P, Bratasz A, Powell KA, Simonetti OP, Higgins RS, Kilic A, Mohler PJ, Janssen PM, Weiss R, Hummel JD, Fedorov VV. Hansen BJ, et al. Among authors: higgins rs. Eur Heart J. 2015 Sep 14;36(35):2390-401. doi: 10.1093/eurheartj/ehv233. Epub 2015 Jun 8. Eur Heart J. 2015. PMID: 26059724 Free PMC article.
Molecular Mapping of Sinoatrial Node HCN Channel Expression in the Human Heart.
Li N, Csepe TA, Hansen BJ, Dobrzynski H, Higgins RS, Kilic A, Mohler PJ, Janssen PM, Rosen MR, Biesiadecki BJ, Fedorov VV. Li N, et al. Among authors: higgins rs. Circ Arrhythm Electrophysiol. 2015 Oct;8(5):1219-27. doi: 10.1161/CIRCEP.115.003070. Epub 2015 Aug 24. Circ Arrhythm Electrophysiol. 2015. PMID: 26304511 Free PMC article.
The Frank-Starling mechanism involves deceleration of cross-bridge kinetics and is preserved in failing human right ventricular myocardium.
Milani-Nejad N, Canan BD, Elnakish MT, Davis JP, Chung JH, Fedorov VV, Binkley PF, Higgins RS, Kilic A, Mohler PJ, Janssen PM. Milani-Nejad N, et al. Among authors: higgins rs. Am J Physiol Heart Circ Physiol. 2015 Dec 15;309(12):H2077-86. doi: 10.1152/ajpheart.00685.2015. Epub 2015 Oct 9. Am J Physiol Heart Circ Physiol. 2015. PMID: 26453335 Free PMC article.
SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia.
Musa H, Kline CF, Sturm AC, Murphy N, Adelman S, Wang C, Yan H, Johnson BL, Csepe TA, Kilic A, Higgins RS, Janssen PM, Fedorov VV, Weiss R, Salazar C, Hund TJ, Pitt GS, Mohler PJ. Musa H, et al. Among authors: higgins rs. Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12528-33. doi: 10.1073/pnas.1516430112. Epub 2015 Sep 21. Proc Natl Acad Sci U S A. 2015. PMID: 26392562 Free PMC article.
Etiology-dependent impairment of relaxation kinetics in right ventricular end-stage failing human myocardium.
Chung JH, Martin BL, Canan BD, Elnakish MT, Milani-Nejad N, Saad NS, Repas SJ, Schultz JEJ, Murray JD, Slabaugh JL, Gearinger RL, Conkle J, Karaze T, Rastogi N, Chen MP, Crecelius W, Peczkowski KK, Ziolo MT, Fedorov VV, Kilic A, Whitson BA, Higgins RSD, Smith SA, Mohler PJ, Binkley PF, Janssen PML. Chung JH, et al. J Mol Cell Cardiol. 2018 Aug;121:81-93. doi: 10.1016/j.yjmcc.2018.07.005. Epub 2018 Jul 5. J Mol Cell Cardiol. 2018. PMID: 29981798 Free PMC article.
Surgical Treatment of Heart Failure.
Higgins RSD, Kilic A, Tang DG. Higgins RSD, et al. Surg Clin North Am. 2017 Aug;97(4):923-946. doi: 10.1016/j.suc.2017.04.003. Surg Clin North Am. 2017. PMID: 28728723 Review.
204 results