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Actin dynamics: growth from dendritic branches.
Nicholson-Dykstra S, Higgs HN, Harris ES. Nicholson-Dykstra S, et al. Among authors: higgs hn. Curr Biol. 2005 May 10;15(9):R346-57. doi: 10.1016/j.cub.2005.04.029. Curr Biol. 2005. PMID: 15886095 Review.
Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex.
Machesky LM, Mullins RD, Higgs HN, Kaiser DA, Blanchoin L, May RC, Hall ME, Pollard TD. Machesky LM, et al. Among authors: higgs hn. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3739-44. doi: 10.1073/pnas.96.7.3739. Proc Natl Acad Sci U S A. 1999. PMID: 10097107 Free PMC article.
The Arp2/3 complex is essential for the actin-based motility of Listeria monocytogenes.
May RC, Hall ME, Higgs HN, Pollard TD, Chakraborty T, Wehland J, Machesky LM, Sechi AS. May RC, et al. Among authors: higgs hn. Curr Biol. 1999 Jul 15;9(14):759-62. doi: 10.1016/s0960-9822(99)80337-6. Curr Biol. 1999. PMID: 10421578
Cdc42-induced actin filaments are protected from capping protein.
Huang M, Yang C, Schafer DA, Cooper JA, Higgs HN, Zigmond SH. Huang M, et al. Among authors: higgs hn. Curr Biol. 1999 Sep 9;9(17):979-82. doi: 10.1016/s0960-9822(99)80428-x. Curr Biol. 1999. PMID: 10508585
Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins.
Blanchoin L, Amann KJ, Higgs HN, Marchand JB, Kaiser DA, Pollard TD. Blanchoin L, et al. Among authors: higgs hn. Nature. 2000 Apr 27;404(6781):1007-11. doi: 10.1038/35010008. Nature. 2000. PMID: 10801131
Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins.
Higgs HN, Pollard TD. Higgs HN, et al. Annu Rev Biochem. 2001;70:649-76. doi: 10.1146/annurev.biochem.70.1.649. Annu Rev Biochem. 2001. PMID: 11395419 Review.
Actin nucleation: nucleation-promoting factors are not all equal.
Higgs HN. Higgs HN. Curr Biol. 2001 Dec 11;11(24):R1009-12. doi: 10.1016/s0960-9822(01)00612-1. Curr Biol. 2001. PMID: 11747836 Review.
Actin nucleation: cortactin caught in the act.
Higgs HN. Higgs HN. Curr Biol. 2002 Sep 3;12(17):R593-5. doi: 10.1016/s0960-9822(02)01101-6. Curr Biol. 2002. PMID: 12225681
Listeria motility: biophysics pushes things forward.
Merz AJ, Higgs HN. Merz AJ, et al. Among authors: higgs hn. Curr Biol. 2003 Apr 15;13(8):R302-4. doi: 10.1016/s0960-9822(03)00231-8. Curr Biol. 2003. PMID: 12699639 Review.
The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition.
Li F, Higgs HN. Li F, et al. Among authors: higgs hn. Curr Biol. 2003 Aug 5;13(15):1335-40. doi: 10.1016/s0960-9822(03)00540-2. Curr Biol. 2003. PMID: 12906795
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