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Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation.
Mielke LA, Jones SA, Raverdeau M, Higgs R, Stefanska A, Groom JR, Misiak A, Dungan LS, Sutton CE, Streubel G, Bracken AP, Mills KH. Mielke LA, et al. Among authors: higgs r. J Exp Med. 2013 Jun 3;210(6):1117-24. doi: 10.1084/jem.20121588. Epub 2013 May 20. J Exp Med. 2013. PMID: 23690441 Free PMC article.
Enhanced interferon regulatory factor 3 binding to the interleukin-23p19 promoter correlates with enhanced interleukin-23 expression in systemic lupus erythematosus.
Smith S, Gabhann JN, Higgs R, Stacey K, Wahren-Herlenius M, Espinosa A, Totaro MG, Sica A, Ball E, Bell A, Johnston J, Browne P, O'Neill L, Kearns G, Jefferies CA. Smith S, et al. Among authors: higgs r. Arthritis Rheum. 2012 May;64(5):1601-9. doi: 10.1002/art.33494. Arthritis Rheum. 2012. PMID: 22127978
Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway.
Espinosa A, Dardalhon V, Brauner S, Ambrosi A, Higgs R, Quintana FJ, Sjöstrand M, Eloranta ML, Ní Gabhann J, Winqvist O, Sundelin B, Jefferies CA, Rozell B, Kuchroo VK, Wahren-Herlenius M. Espinosa A, et al. Among authors: higgs r. J Exp Med. 2009 Aug 3;206(8):1661-71. doi: 10.1084/jem.20090585. Epub 2009 Jul 27. J Exp Med. 2009. PMID: 19635858 Free PMC article.
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