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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1984 1
1985 2
1987 1
1990 5
1991 3
1992 4
1993 5
1994 6
1995 5
1996 4
1997 9
1998 10
1999 6
2000 12
2001 9
2002 7
2003 15
2004 12
2005 11
2006 12
2007 15
2008 12
2009 15
2010 13
2011 19
2012 23
2013 20
2014 29
2015 36
2016 33
2017 31
2018 22
2019 23
2020 28
2021 38
2022 38
2023 27

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519 results

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Page 1
Glioma targeted therapy: insight into future of molecular approaches.
Yang K, Wu Z, Zhang H, Zhang N, Wu W, Wang Z, Dai Z, Zhang X, Zhang L, Peng Y, Ye W, Zeng W, Liu Z, Cheng Q. Yang K, et al. Mol Cancer. 2022 Feb 8;21(1):39. doi: 10.1186/s12943-022-01513-z. Mol Cancer. 2022. PMID: 35135556 Free PMC article. Review.
Generally, circumscribed gliomas are usually benign and recommended to early complete resection, with chemotherapy if necessary. Diffuse gliomas and other high-grade gliomas according to their molecule subtype are slightly intractable, with necessity of chemotherapy …
Generally, circumscribed gliomas are usually benign and recommended to early complete resection, with chemotherapy if necessary. Diffuse gli …
Glioblastoma and Other Primary Brain Malignancies in Adults: A Review.
Schaff LR, Mellinghoff IK. Schaff LR, et al. JAMA. 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. JAMA. 2023. PMID: 36809318 Review.
Magnetic resonance imaging before and after a gadolinium-based contrast agent is the preferred imaging modality for evaluating brain tumors. Diagnosis requires tumor biopsy with consideration of histopathological and molecular characteristics. Treatment varies by tumor …
Magnetic resonance imaging before and after a gadolinium-based contrast agent is the preferred imaging modality for evaluating brain tumors. …
Glioblastoma: pathology, molecular mechanisms and markers.
Aldape K, Zadeh G, Mansouri S, Reifenberger G, von Deimling A. Aldape K, et al. Acta Neuropathol. 2015 Jun;129(6):829-48. doi: 10.1007/s00401-015-1432-1. Epub 2015 May 6. Acta Neuropathol. 2015. PMID: 25943888 Review.
The current WHO definition of GBM relies on the presence of high-grade astrocytic neoplasm with the presence of either microvascular proliferation and/or tumor necrosis. ...Alternatively, an astrocytic tumor that fits the current histolog …
The current WHO definition of GBM relies on the presence of high-grade astrocytic neoplasm with the presence of either …
Emerging therapies for glioblastoma: current state and future directions.
Rong L, Li N, Zhang Z. Rong L, et al. J Exp Clin Cancer Res. 2022 Apr 15;41(1):142. doi: 10.1186/s13046-022-02349-7. J Exp Clin Cancer Res. 2022. PMID: 35428347 Free PMC article. Review.
Glioblastoma (GBM) is the most common high-grade primary malignant brain tumor with an extremely poor prognosis. ...
Glioblastoma (GBM) is the most common high-grade primary malignant brain tumor with an extremely poor prognosis. ...
Childhood brain tumors: current management, biological insights, and future directions.
Pollack IF, Agnihotri S, Broniscer A. Pollack IF, et al. J Neurosurg Pediatr. 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. J Neurosurg Pediatr. 2019. PMID: 30835699 Free PMC article. Review.
During the last several years, however, remarkable advances in our understanding of the molecular underpinnings of these tumors have occurred as a result of high-resolution genomic, epigenetic, and transcriptomic profiling, which have provided insights for improved tumo …
During the last several years, however, remarkable advances in our understanding of the molecular underpinnings of these tumors have occurre …
Clinical implications of the 2021 edition of the WHO classification of central nervous system tumours.
Horbinski C, Berger T, Packer RJ, Wen PY. Horbinski C, et al. Nat Rev Neurol. 2022 Sep;18(9):515-529. doi: 10.1038/s41582-022-00679-w. Epub 2022 Jun 21. Nat Rev Neurol. 2022. PMID: 35729337 Review.
Compared with the 2016 scheme, the new classification incorporates even more molecular alterations into the diagnosis of many tumours and reorganizes gliomas into adult-type diffuse gliomas, paediatric-type diffuse low-grade and high-grade gliomas, circumscri …
Compared with the 2016 scheme, the new classification incorporates even more molecular alterations into the diagnosis of many tumours and re …
Major Features of the 2021 WHO Classification of CNS Tumors.
Smith HL, Wadhwani N, Horbinski C. Smith HL, et al. Neurotherapeutics. 2022 Oct;19(6):1691-1704. doi: 10.1007/s13311-022-01249-0. Epub 2022 May 16. Neurotherapeutics. 2022. PMID: 35578106 Free PMC article. Review.
Many tumors have also been reconceptualized into new "supercategories," including adult-type diffuse gliomas, pediatric-type diffuse low- and high-grade gliomas, and circumscribed astrocytic gliomas. Some entirely new tumors are in this scheme, particularly p …
Many tumors have also been reconceptualized into new "supercategories," including adult-type diffuse gliomas, pediatric-type diffuse low- an …
The management of low-grade gliomas in adults.
Morshed RA, Young JS, Hervey-Jumper SL, Berger MS. Morshed RA, et al. J Neurosurg Sci. 2019 Aug;63(4):450-457. doi: 10.23736/S0390-5616.19.04701-5. Epub 2019 Mar 27. J Neurosurg Sci. 2019. PMID: 30916536 Review.
Low grade gliomas (LGGs) are WHO grade II tumors that affect mostly adult patients and include diffuse astrocytomas and oligodendrogliomas. ...In general, the current management of LGG favors maximum upfront resection with consideration of combined chemoradiation fo …
Low grade gliomas (LGGs) are WHO grade II tumors that affect mostly adult patients and include diffuse astrocytomas and oligod …
Applications of radiomics and machine learning for radiotherapy of malignant brain tumors.
Kocher M, Ruge MI, Galldiks N, Lohmann P. Kocher M, et al. Strahlenther Onkol. 2020 Oct;196(10):856-867. doi: 10.1007/s00066-020-01626-8. Epub 2020 May 11. Strahlenther Onkol. 2020. PMID: 32394100 Free PMC article. Review.
RESULTS: Feature-based radiomics and deep learning-based machine learning methods can be used to improve brain tumor diagnostics and automate various steps of radiotherapy planning. In glioma patients, important applications are the determination of WHO grade and mo …
RESULTS: Feature-based radiomics and deep learning-based machine learning methods can be used to improve brain tumor diagnostics and …
Overcoming the blood-brain tumor barrier for effective glioblastoma treatment.
van Tellingen O, Yetkin-Arik B, de Gooijer MC, Wesseling P, Wurdinger T, de Vries HE. van Tellingen O, et al. Drug Resist Updat. 2015 Mar;19:1-12. doi: 10.1016/j.drup.2015.02.002. Epub 2015 Mar 6. Drug Resist Updat. 2015. PMID: 25791797 Review.
The high metabolic demands of high-grade glioma create hypoxic areas that trigger increased expression of VEGF and angiogenesis, leading to the formation of abnormal vessels and a dysfunctional BBTB. ...While our knowledge about the molecular biology of gliom …
The high metabolic demands of high-grade glioma create hypoxic areas that trigger increased expression of VEGF and angi …
519 results