High KA - Search Results

1

Lack of germline transmission of vector sequences following systemic administration of recombinant AAV-2 vector in males.

Arruda VR, Fields PA, Milner R, Wainwright L, De Miguel MP, Donovan PJ, Herzog RW, Nichols TC, Biegel JA, Razavi M, Dake M, Huff D, Flake AW, Couto L, Kay MA, High KA. Arruda VR, et al. Among authors: high ka. Mol Ther. 2001 Dec;4(6):586-92. doi: 10.1006/mthe.2001.0491. Mol Ther. 2001. PMID: 11735343 Free article.

2

Influence of vector dose on factor IX-specific T and B cell responses in muscle-directed gene therapy.

Herzog RW, Fields PA, Arruda VR, Brubaker JO, Armstrong E, McClintock D, Bellinger DA, Couto LB, Nichols TC, High KA. Herzog RW, et al. Among authors: high ka. Hum Gene Ther. 2002 Jul 20;13(11):1281-91. doi: 10.1089/104303402760128513. Hum Gene Ther. 2002. PMID: 12162811

3

AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.

Manno CS, Chew AJ, Hutchison S, Larson PJ, Herzog RW, Arruda VR, Tai SJ, Ragni MV, Thompson A, Ozelo M, Couto LB, Leonard DG, Johnson FA, McClelland A, Scallan C, Skarsgard E, Flake AW, Kay MA, High KA, Glader B. Manno CS, et al. Among authors: high ka. Blood. 2003 Apr 15;101(8):2963-72. doi: 10.1182/blood-2002-10-3296. Epub 2002 Dec 19. Blood. 2003. PMID: 12515715 Free article.

4

Safety and efficacy of factor IX gene transfer to skeletal muscle in murine and canine hemophilia B models by adeno-associated viral vector serotype 1.

Arruda VR, Schuettrumpf J, Herzog RW, Nichols TC, Robinson N, Lotfi Y, Mingozzi F, Xiao W, Couto LB, High KA. Arruda VR, et al. Among authors: high ka. Blood. 2004 Jan 1;103(1):85-92. doi: 10.1182/blood-2003-05-1446. Epub 2003 Sep 11. Blood. 2004. PMID: 12969984 Free PMC article.

5

Therapeutic levels of factor IX expression using a muscle-specific promoter and adeno-associated virus serotype 1 vector.

Liu YL, Mingozzi F, Rodriguéz-Colôn SM, Joseph S, Dobrzynski E, Suzuki T, High KA, Herzog RW. Liu YL, et al. Among authors: high ka. Hum Gene Ther. 2004 Aug;15(8):783-92. doi: 10.1089/1043034041648453. Hum Gene Ther. 2004. PMID: 15319035

6

Regional intravascular delivery of AAV-2-F.IX to skeletal muscle achieves long-term correction of hemophilia B in a large animal model.

Arruda VR, Stedman HH, Nichols TC, Haskins ME, Nicholson M, Herzog RW, Couto LB, High KA. Arruda VR, et al. Among authors: high ka. Blood. 2005 May 1;105(9):3458-64. doi: 10.1182/blood-2004-07-2908. Epub 2004 Oct 12. Blood. 2005. PMID: 15479726 Free PMC article.

7

Persistent expression of hF.IX After tolerance induction by in utero or neonatal administration of AAV-1-F.IX in hemophilia B mice.

Sabatino DE, Mackenzie TC, Peranteau W, Edmonson S, Campagnoli C, Liu YL, Flake AW, High KA. Sabatino DE, et al. Among authors: high ka. Mol Ther. 2007 Sep;15(9):1677-85. doi: 10.1038/sj.mt.6300219. Epub 2007 Jun 12. Mol Ther. 2007. PMID: 17565352 Free article.

8

Host and vector-dependent effects on the risk of germline transmission of AAV vectors.

Favaro P, Downey HD, Zhou JS, Wright JF, Hauck B, Mingozzi F, High KA, Arruda VR. Favaro P, et al. Among authors: high ka. Mol Ther. 2009 Jun;17(6):1022-30. doi: 10.1038/mt.2009.56. Epub 2009 Mar 17. Mol Ther. 2009. PMID: 19293773 Free PMC article.

9

Impact of the underlying mutation and the route of vector administration on immune responses to factor IX in gene therapy for hemophilia B.

Cao O, Hoffman BE, Moghimi B, Nayak S, Cooper M, Zhou S, Ertl HC, High KA, Herzog RW. Cao O, et al. Among authors: high ka. Mol Ther. 2009 Oct;17(10):1733-42. doi: 10.1038/mt.2009.159. Epub 2009 Jul 14. Mol Ther. 2009. PMID: 19603001 Free PMC article.

10

Safety of AAV factor IX peripheral transvenular gene delivery to muscle in hemophilia B dogs.

Haurigot V, Mingozzi F, Buchlis G, Hui DJ, Chen Y, Basner-Tschakarjan E, Arruda VR, Radu A, Franck HG, Wright JF, Zhou S, Stedman HH, Bellinger DA, Nichols TC, High KA. Haurigot V, et al. Among authors: high ka. Mol Ther. 2010 Jul;18(7):1318-29. doi: 10.1038/mt.2010.73. Epub 2010 Apr 27. Mol Ther. 2010. PMID: 20424599 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

239 results

Search Page