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High-Throughput and Cost-Effective Characterization of Induced Pluripotent Stem Cells.
D'Antonio M, Woodruff G, Nathanson JL, D'Antonio-Chronowska A, Arias A, Matsui H, Williams R, Herrera C, Reyna SM, Yeo GW, Goldstein LSB, Panopoulos AD, Frazer KA. D'Antonio M, et al. Stem Cell Reports. 2017 Apr 11;8(4):1101-1111. doi: 10.1016/j.stemcr.2017.03.011. Stem Cell Reports. 2017. PMID: 28410643 Free PMC article.
Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) offers the possibility of studying the molecular mechanisms underlying human diseases in cell types difficult to extract from living patients, such as neurons and cardiomyocyt …
Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) offers the possibility of studying …
Generation of Ventricular-Like HiPSC-Derived Cardiomyocytes and High-Quality Cell Preparations for Calcium Handling Characterization.
Oh JG, Dave J, Kho C, Stillitano F. Oh JG, et al. J Vis Exp. 2020 Jan 17;(155). doi: 10.3791/60135. J Vis Exp. 2020. PMID: 32009647
Human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) provide a valuable human source for studying the basic science of calcium (Ca(2+)) handling and signaling pathways as well as high-throughput drug screening and toxicity assay …
Human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) provide a valuable human source for studying the …
Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell.
Nishi M, Akutsu H, Kudoh A, Kimura H, Yamamoto N, Umezawa A, Lee SW, Ryo A. Nishi M, et al. Oncotarget. 2014 Sep 30;5(18):8665-80. doi: 10.18632/oncotarget.2356. Oncotarget. 2014. PMID: 25228591 Free PMC article.
Novel drugs that target CSCs can potentially eliminate the tumor initiating cell population therefore resulting in complete cure of the cancer. We recently established a CSC-like model using induced pluripotent stem cell (iPSC) technology to reprogram and par …
Novel drugs that target CSCs can potentially eliminate the tumor initiating cell population therefore resulting in complete cure of the canc …