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106 results

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Page 1
High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer.
Böttger F, Vallés-Martí A, Cahn L, Jimenez CR. Böttger F, et al. J Exp Clin Cancer Res. 2021 Oct 30;40(1):343. doi: 10.1186/s13046-021-02134-y. J Exp Clin Cancer Res. 2021. PMID: 34717701 Free PMC article. Review.
Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer agent when administered intravenously and in high doses (high-dose IVC). ...In addition, an outlook on future implications of high-dose …
Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer agent when administered intr …
High-Dose Vitamin C in Advanced-Stage Cancer Patients.
Zasowska-Nowak A, Nowak PJ, Ciałkowska-Rysz A. Zasowska-Nowak A, et al. Nutrients. 2021 Feb 26;13(3):735. doi: 10.3390/nu13030735. Nutrients. 2021. PMID: 33652579 Free PMC article. Review.
High-dose intravenously administered vitamin C (IVC) is widely used in cancer patients by complementary and alternative medicine practitioners. ...We also have not found the rationale for the use of IVC to increase the effectiveness of ch …
High-dose intravenously administered vitamin C (IVC) is widely used in cancer patients by compleme …
A Randomized, Open-Label, Multicenter, Phase 3 Study of High-Dose Vitamin C Plus FOLFOX Bevacizumab versus FOLFOX Bevacizumab in Unresectable Untreated Metastatic Colorectal Cancer (VITALITY Study).
Wang F, He MM, Xiao J, Zhang YQ, Yuan XL, Fang WJ, Zhang Y, Wang W, Hu XH, Ma ZG, Yao YC, Zhuang ZX, Zhou FX, Ying JE, Yuan Y, Zou QF, Guo ZQ, Wu XY, Jin Y, Mai ZJ, Wang ZQ, Qiu H, Guo Y, Shi SM, Chen SZ, Luo HY, Zhang DS, Wang FH, Li YH, Xu RH. Wang F, et al. Clin Cancer Res. 2022 Oct 3;28(19):4232-4239. doi: 10.1158/1078-0432.CCR-22-0655. Clin Cancer Res. 2022. PMID: 35929990 Free PMC article. Clinical Trial.
PURPOSE: To compare the efficacy and safety of high-dose vitamin C plus FOLFOX bevacizumab versus FOLFOX bevacizumab as first-line treatment in patients with metastatic colorectal cancer (mCRC). PATIENTS AND METHODS: Between 2017 and 2019, histo …
PURPOSE: To compare the efficacy and safety of high-dose vitamin C plus FOLFOX bevacizumab versus FOLFOX bevaciz …
High-Dose Vitamin C: Preclinical Evidence for Tailoring Treatment in Cancer Patients.
Giansanti M, Karimi T, Faraoni I, Graziani G. Giansanti M, et al. Cancers (Basel). 2021 Mar 20;13(6):1428. doi: 10.3390/cancers13061428. Cancers (Basel). 2021. PMID: 33804775 Free PMC article. Review.
High-dose vitamin C has been proposed as a potential therapeutic approach for patients with advanced tumors who failed previous treatment with chemotherapy. Due to vitamin C complex pharmacokinetics, only intravenous administration …
High-dose vitamin C has been proposed as a potential therapeutic approach for patients with advanced tumors who …
[Does high-dose intravenous vitamin C has anti-cancer activity ?].
Courtes MG, Baudoux N, Astaras C, Fernandez E. Courtes MG, et al. Rev Med Suisse. 2022 May 18;18(782):1002-1006. doi: 10.53738/REVMED.2022.18.782.1002. Rev Med Suisse. 2022. PMID: 35583280 Clinical Trial. French.
High-dose intravenously (i.v) vitamin C in cancer patients is controversial. Numerous studies carried out on cancer cell lines and animal models demonstrated that millimolar vitamin C concentrations inhibit tumor cell …
High-dose intravenously (i.v) vitamin C in cancer patients is controversial. Numerous studies carr …
Review of high-dose intravenous vitamin C as an anticancer agent.
Wilson MK, Baguley BC, Wall C, Jameson MB, Findlay MP. Wilson MK, et al. Asia Pac J Clin Oncol. 2014 Mar;10(1):22-37. doi: 10.1111/ajco.12173. Asia Pac J Clin Oncol. 2014. PMID: 24571058 Review.
In the 1970s, Pauling and Cameron reported increased survival of patients with advanced cancer treated with high-dose intravenous (IV) vitamin C (L-ascorbate, ascorbic acid). ...Currently, the use of high-dose …
In the 1970s, Pauling and Cameron reported increased survival of patients with advanced cancer treated with high-dose …
High-Dose Intravenous Vitamin C Combined with Docetaxel in Men with Metastatic Castration-Resistant Prostate Cancer: A Randomized Placebo-Controlled Phase II Trial.
Paller CJ, Zahurak ML, Mandl A, Metri NA, Lalji A, Heath E, Kelly WK, Hoimes C, Barata P, Taksey J, Garrison DA, Patra K, Milne GL, Anders NM, Nauroth JM, Durham JN, Marshall CH, Markowski MC, Eisenberger MA, Antonarakis ES, Carducci MA, Denmeade SR, Levine M. Paller CJ, et al. Cancer Res Commun. 2024 Aug 1;4(8):2174-2182. doi: 10.1158/2767-9764.CRC-24-0225. Cancer Res Commun. 2024. PMID: 39076107 Free PMC article. Clinical Trial.
High-dose intravenous vitamin C (HDIVC) administered to produce pharmacologic concentrations shows promise in preclinical models and small clinical trials, but larger prospective randomized trials are lacking. ...Secondary endpoints included ove …
High-dose intravenous vitamin C (HDIVC) administered to produce pharmacologic concentrations shows promis …
High Dose Intravenous Vitamin C as Adjunctive Therapy for COVID-19 Patients with Cancer: Two Cases.
Guo G, Chen Q, Luo G, Meng Z, Lei P, Chen P, Drisko JA. Guo G, et al. Life (Basel). 2022 Feb 24;12(3):335. doi: 10.3390/life12030335. Life (Basel). 2022. PMID: 35330086 Free PMC article.
To date, there are few treatments with proven efficacy for COVID-19. Vitamin C administered intravenously (IVC) has been extensively investigated in cancer treatment with a known safety profile and has been proposed to play a role in managing COVID-19. …
To date, there are few treatments with proven efficacy for COVID-19. Vitamin C administered intravenously (IVC) has bee …
Effect of High-dose Vitamin C Combined With Anti-cancer Treatment on Breast Cancer Cells.
Lee SJ, Jeong JH, Lee IH, Lee J, Jung JH, Park HY, Lee DH, Chae YS. Lee SJ, et al. Anticancer Res. 2019 Feb;39(2):751-758. doi: 10.21873/anticanres.13172. Anticancer Res. 2019. PMID: 30711954
BACKGROUND/AIM: The anti-cancer effect of high doses of intravenous vitamin C (high-dose vitamin C) remains controversial despite growing evidence that high-dose vitamin C exerts anti-tumorigenic …
BACKGROUND/AIM: The anti-cancer effect of high doses of intravenous vitamin C (high-dose vitami …
The Effect of High Dose Intravenous Vitamin C During Radiotherapy on Breast Cancer Patients' Neutrophil-Lymphocyte Ratio.
Park H, Kang J, Choi J, Heo S, Lee DH. Park H, et al. J Altern Complement Med. 2020 Nov;26(11):1039-1046. doi: 10.1089/acm.2020.0138. Epub 2020 Sep 1. J Altern Complement Med. 2020. PMID: 32876471
The experimental group was divided into two groups according to the dose administrated: a low-dose vitamin C group (less than 1 g/kg, 52 patients) and a high-dose vitamin C group (more than 1 g/kg, 18 patients). ...In this observational s …
The experimental group was divided into two groups according to the dose administrated: a low-dose vitamin C group (less than …
106 results