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The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth of Legionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE.
Weber SS, Ragaz C, Hilbi H. Weber SS, et al. Cell Microbiol. 2009 Mar;11(3):442-60. doi: 10.1111/j.1462-5822.2008.01266.x. Epub 2008 Nov 13. Cell Microbiol. 2009. PMID: 19021631
Divergent Evolution of Legionella RCC1 Repeat Effectors Defines the Range of Ran GTPase Cycle Targets.
Swart AL, Steiner B, Gomez-Valero L, Schütz S, Hannemann M, Janning P, Irminger M, Rothmeier E, Buchrieser C, Itzen A, Panse VG, Hilbi H. Swart AL, et al. Among authors: hilbi h. mBio. 2020 Mar 24;11(2):e00405-20. doi: 10.1128/mBio.00405-20. mBio. 2020. PMID: 32209684 Free PMC article.
Icm/dot-dependent upregulation of phagocytosis by Legionella pneumophila.
Hilbi H, Segal G, Shuman HA. Hilbi H, et al. Mol Microbiol. 2001 Nov;42(3):603-17. doi: 10.1046/j.1365-2958.2001.02645.x. Mol Microbiol. 2001. PMID: 11722729
Enzymic and genetic basis for bacterial growth on malonate.
Dimroth P, Hilbi H. Dimroth P, et al. Mol Microbiol. 1997 Jul;25(1):3-10. doi: 10.1046/j.1365-2958.1997.4611824.x. Mol Microbiol. 1997. PMID: 11902724 Review.
Planktonic replication is essential for biofilm formation by Legionella pneumophila in a complex medium under static and dynamic flow conditions.
Mampel J, Spirig T, Weber SS, Haagensen JA, Molin S, Hilbi H. Mampel J, et al. Appl Environ Microbiol. 2006 Apr;72(4):2885-95. doi: 10.1128/AEM.72.4.2885-2895.2006. Appl Environ Microbiol. 2006. PMID: 16597995 Free PMC article.
Cholesterol is required to trigger caspase-1 activation and macrophage apoptosis after phagosomal escape of Shigella.
Schroeder GN, Hilbi H. Schroeder GN, et al. Cell Microbiol. 2007 Jan;9(1):265-78. doi: 10.1111/j.1462-5822.2006.00787.x. Epub 2006 Aug 22. Cell Microbiol. 2007. PMID: 16925787
Contrarily, the activation of caspase-1 and cytotoxicity triggered by the K+/H+ antiport ionophore nigericin or by ATP was not affected or even increased by MCD. ...
Contrarily, the activation of caspase-1 and cytotoxicity triggered by the K+/H+ antiport ionophore nigericin or by ATP was not affect …
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