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From SARS to MERS: 10 years of research on highly pathogenic human coronaviruses.
Hilgenfeld R, Peiris M. Hilgenfeld R, et al. Antiviral Res. 2013 Oct;100(1):286-95. doi: 10.1016/j.antiviral.2013.08.015. Epub 2013 Sep 6. Antiviral Res. 2013. PMID: 24012996 Free PMC article. Review.
Computer-Aided Structure Based Drug Design Approaches for the Discovery of New Anti-CHIKV Agents.
Jadav SS, Sinha BN, Hilgenfeld R, Jayaprakash V. Jadav SS, et al. Among authors: hilgenfeld r. Curr Comput Aided Drug Des. 2017 Nov 10;13(4):346-361. doi: 10.2174/1573409913666170309145308. Curr Comput Aided Drug Des. 2017. PMID: 28294048 Review.
Recent advances in targeting viral proteases for the discovery of novel antivirals.
Steuber H, Hilgenfeld R. Steuber H, et al. Among authors: hilgenfeld r. Curr Top Med Chem. 2010;10(3):323-45. doi: 10.2174/156802610790725470. Curr Top Med Chem. 2010. PMID: 20166951 Review.
Third Tofo Advanced Study Week on Emerging and Re-emerging Viruses, 2018.
Badolo A, Burt F, Daniel S, Fearns R, Gudo ES, Kielian M, Lescar J, Shi Y, von Brunn A, Weiss SR, Hilgenfeld R. Badolo A, et al. Among authors: hilgenfeld r. Antiviral Res. 2019 Feb;162:142-150. doi: 10.1016/j.antiviral.2018.12.015. Epub 2018 Dec 28. Antiviral Res. 2019. PMID: 30597184 Free PMC article. Review.
Viral Entry and NS1 as Potential Antiviral Drug Targets.
de Silva AM, Rey FA, Young PR, Hilgenfeld R, Vasudevan SG. de Silva AM, et al. Among authors: hilgenfeld r. Adv Exp Med Biol. 2018;1062:107-113. doi: 10.1007/978-981-10-8727-1_8. Adv Exp Med Biol. 2018. PMID: 29845528 Review.
Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein.
Lei J, Kusov Y, Hilgenfeld R. Lei J, et al. Among authors: hilgenfeld r. Antiviral Res. 2018 Jan;149:58-74. doi: 10.1016/j.antiviral.2017.11.001. Epub 2017 Nov 8. Antiviral Res. 2018. PMID: 29128390 Free PMC article. Review.
Structure and functionality in flavivirus NS-proteins: perspectives for drug design.
Bollati M, Alvarez K, Assenberg R, Baronti C, Canard B, Cook S, Coutard B, Decroly E, de Lamballerie X, Gould EA, Grard G, Grimes JM, Hilgenfeld R, Jansson AM, Malet H, Mancini EJ, Mastrangelo E, Mattevi A, Milani M, Moureau G, Neyts J, Owens RJ, Ren J, Selisko B, Speroni S, Steuber H, Stuart DI, Unge T, Bolognesi M. Bollati M, et al. Among authors: hilgenfeld r. Antiviral Res. 2010 Aug;87(2):125-48. doi: 10.1016/j.antiviral.2009.11.009. Epub 2009 Nov 27. Antiviral Res. 2010. PMID: 19945487 Free PMC article. Review.
Antiviral strategies to control calicivirus infections.
Rohayem J, Bergmann M, Gebhardt J, Gould E, Tucker P, Mattevi A, Unge T, Hilgenfeld R, Neyts J. Rohayem J, et al. Among authors: hilgenfeld r. Antiviral Res. 2010 Aug;87(2):162-78. doi: 10.1016/j.antiviral.2010.05.002. Epub 2010 May 21. Antiviral Res. 2010. PMID: 20471996 Free PMC article. Review.
Extended substrate specificity and first potent irreversible inhibitor/activity-based probe design for Zika virus NS2B-NS3 protease.
Rut W, Zhang L, Kasperkiewicz P, Poreba M, Hilgenfeld R, Drąg M. Rut W, et al. Among authors: hilgenfeld r. Antiviral Res. 2017 Mar;139:88-94. doi: 10.1016/j.antiviral.2016.12.018. Epub 2016 Dec 26. Antiviral Res. 2017. PMID: 28034744
p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1.
Ma-Lauer Y, Carbajo-Lozoya J, Hein MY, Müller MA, Deng W, Lei J, Meyer B, Kusov Y, von Brunn B, Bairad DR, Hünten S, Drosten C, Hermeking H, Leonhardt H, Mann M, Hilgenfeld R, von Brunn A. Ma-Lauer Y, et al. Among authors: hilgenfeld r. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5192-201. doi: 10.1073/pnas.1603435113. Epub 2016 Aug 12. Proc Natl Acad Sci U S A. 2016. PMID: 27519799 Free PMC article.
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