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Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?
Bellingham SA, Guo BB, Coleman BM, Hill AF. Bellingham SA, et al. Among authors: hill af. Front Physiol. 2012 May 3;3:124. doi: 10.3389/fphys.2012.00124. eCollection 2012. Front Physiol. 2012. PMID: 22563321 Free PMC article.
Novel prion protein insert mutation associated with prolonged neurodegenerative illness.
Lewis V, Collins S, Hill AF, Boyd A, McLean CA, Smith M, Masters CL. Lewis V, et al. Among authors: hill af. Neurology. 2003 May 27;60(10):1620-4. doi: 10.1212/01.wnl.0000065887.14609.0e. Neurology. 2003. PMID: 12771252
Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
Nunan J, Williamson NA, Hill AF, Sernee MF, Masters CL, Small DH. Nunan J, et al. Among authors: hill af. J Neurosci Res. 2003 Nov 1;74(3):378-85. doi: 10.1002/jnr.10646. J Neurosci Res. 2003. PMID: 14598314
Delineating common molecular mechanisms in Alzheimer's and prion diseases.
Barnham KJ, Cappai R, Beyreuther K, Masters CL, Hill AF. Barnham KJ, et al. Among authors: hill af. Trends Biochem Sci. 2006 Aug;31(8):465-72. doi: 10.1016/j.tibs.2006.06.006. Epub 2006 Jul 3. Trends Biochem Sci. 2006. PMID: 16820299 Review.
Packaging of prions into exosomes is associated with a novel pathway of PrP processing.
Vella LJ, Sharples RA, Lawson VA, Masters CL, Cappai R, Hill AF. Vella LJ, et al. Among authors: hill af. J Pathol. 2007 Apr;211(5):582-90. doi: 10.1002/path.2145. J Pathol. 2007. PMID: 17334982
The role of exosomes in the processing of proteins associated with neurodegenerative diseases.
Vella LJ, Sharples RA, Nisbet RM, Cappai R, Hill AF. Vella LJ, et al. Among authors: hill af. Eur Biophys J. 2008 Mar;37(3):323-32. doi: 10.1007/s00249-007-0246-z. Epub 2007 Dec 7. Eur Biophys J. 2008. PMID: 18064447 Review.
Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes.
Sharples RA, Vella LJ, Nisbet RM, Naylor R, Perez K, Barnham KJ, Masters CL, Hill AF. Sharples RA, et al. Among authors: hill af. FASEB J. 2008 May;22(5):1469-78. doi: 10.1096/fj.07-9357com. Epub 2008 Jan 2. FASEB J. 2008. PMID: 18171695
Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide.
Price KA, Filiz G, Caragounis A, Du T, Laughton KM, Masters CL, Sharples RA, Hill AF, Li QX, Donnelly PS, Barnham KJ, Crouch PJ, White AR. Price KA, et al. Among authors: hill af. Int J Biochem Cell Biol. 2008;40(9):1901-17. doi: 10.1016/j.biocel.2008.01.033. Epub 2008 Feb 12. Int J Biochem Cell Biol. 2008. PMID: 18346929
Regulation of prion gene expression by transcription factors SP1 and metal transcription factor-1.
Bellingham SA, Coleman LA, Masters CL, Camakaris J, Hill AF. Bellingham SA, et al. Among authors: hill af. J Biol Chem. 2009 Jan 9;284(2):1291-301. doi: 10.1074/jbc.M804755200. Epub 2008 Nov 6. J Biol Chem. 2009. PMID: 18990686
Conformational detection of prion protein with biarsenical labeling and FlAsH fluorescence.
Coleman BM, Nisbet RM, Han S, Cappai R, Hatters DM, Hill AF. Coleman BM, et al. Among authors: hill af. Biochem Biophys Res Commun. 2009 Mar 13;380(3):564-8. doi: 10.1016/j.bbrc.2009.01.120. Epub 2009 Jan 25. Biochem Biophys Res Commun. 2009. PMID: 19285001
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