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Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood.
Cheng L, Sharples RA, Scicluna BJ, Hill AF. Cheng L, et al. Among authors: hill af. J Extracell Vesicles. 2014 Mar 26;3. doi: 10.3402/jev.v3.23743. eCollection 2014. J Extracell Vesicles. 2014. PMID: 24683445 Free PMC article.
Packaging of prions into exosomes is associated with a novel pathway of PrP processing.
Vella LJ, Sharples RA, Lawson VA, Masters CL, Cappai R, Hill AF. Vella LJ, et al. Among authors: hill af. J Pathol. 2007 Apr;211(5):582-90. doi: 10.1002/path.2145. J Pathol. 2007. PMID: 17334982
The role of exosomes in the processing of proteins associated with neurodegenerative diseases.
Vella LJ, Sharples RA, Nisbet RM, Cappai R, Hill AF. Vella LJ, et al. Among authors: hill af. Eur Biophys J. 2008 Mar;37(3):323-32. doi: 10.1007/s00249-007-0246-z. Epub 2007 Dec 7. Eur Biophys J. 2008. PMID: 18064447 Review.
Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes.
Sharples RA, Vella LJ, Nisbet RM, Naylor R, Perez K, Barnham KJ, Masters CL, Hill AF. Sharples RA, et al. Among authors: hill af. FASEB J. 2008 May;22(5):1469-78. doi: 10.1096/fj.07-9357com. Epub 2008 Jan 2. FASEB J. 2008. PMID: 18171695
Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?
Bellingham SA, Guo BB, Coleman BM, Hill AF. Bellingham SA, et al. Among authors: hill af. Front Physiol. 2012 May 3;3:124. doi: 10.3389/fphys.2012.00124. eCollection 2012. Front Physiol. 2012. PMID: 22563321 Free PMC article.
Prion-infected cells regulate the release of exosomes with distinct ultrastructural features.
Coleman BM, Hanssen E, Lawson VA, Hill AF. Coleman BM, et al. Among authors: hill af. FASEB J. 2012 Oct;26(10):4160-73. doi: 10.1096/fj.11-202077. Epub 2012 Jul 5. FASEB J. 2012. PMID: 22767229
Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells.
Bellingham SA, Coleman BM, Hill AF. Bellingham SA, et al. Among authors: hill af. Nucleic Acids Res. 2012 Nov;40(21):10937-49. doi: 10.1093/nar/gks832. Epub 2012 Sep 10. Nucleic Acids Res. 2012. PMID: 22965126 Free PMC article.
The detection of microRNA associated with Alzheimer's disease in biological fluids using next-generation sequencing technologies.
Cheng L, Quek CY, Sun X, Bellingham SA, Hill AF. Cheng L, et al. Among authors: hill af. Front Genet. 2013 Aug 8;4:150. doi: 10.3389/fgene.2013.00150. eCollection 2013. Front Genet. 2013. PMID: 23964286 Free PMC article.
Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in human urine.
Cheng L, Sun X, Scicluna BJ, Coleman BM, Hill AF. Cheng L, et al. Among authors: hill af. Kidney Int. 2014 Aug;86(2):433-44. doi: 10.1038/ki.2013.502. Epub 2013 Dec 18. Kidney Int. 2014. PMID: 24352158
ISEV position paper: extracellular vesicle RNA analysis and bioinformatics.
Hill AF, Pegtel DM, Lambertz U, Leonardi T, O'Driscoll L, Pluchino S, Ter-Ovanesyan D, Nolte-'t Hoen EN. Hill AF, et al. J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22859. eCollection 2013. J Extracell Vesicles. 2013. PMID: 24376909 Free PMC article.
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