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Ecdysone receptors: from the Ashburner model to structural biology.
Hill RJ, Billas IM, Bonneton F, Graham LD, Lawrence MC. Hill RJ, et al. Annu Rev Entomol. 2013;58:251-71. doi: 10.1146/annurev-ento-120811-153610. Epub 2012 Oct 9. Annu Rev Entomol. 2013. PMID: 23072463 Review.
Unprecedented conformational flexibility revealed in the ligand-binding domains of the Bovicola ovis ecdysone receptor (EcR) and ultraspiracle (USP) subunits.
Ren B, Peat TS, Streltsov VA, Pollard M, Fernley R, Grusovin J, Seabrook S, Pilling P, Phan T, Lu L, Lovrecz GO, Graham LD, Hill RJ. Ren B, et al. Among authors: hill rj. Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):1954-64. doi: 10.1107/S1399004714009626. Epub 2014 Jun 29. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 25004972
Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling.
Tohidi-Esfahani D, Lawrence MC, Graham LD, Hannan GN, Simpson AM, Hill RJ. Tohidi-Esfahani D, et al. Among authors: hill rj. Pest Manag Sci. 2011 Nov;67(11):1457-67. doi: 10.1002/ps.2200. Epub 2011 May 18. Pest Manag Sci. 2011. PMID: 21594962
An ecdysone receptor from the pentatomomorphan, Nezara viridula, shows similar affinities for moulting hormones makisterone A and 20-hydroxyecdysone.
Tohidi-Esfahani D, Graham LD, Hannan GN, Simpson AM, Hill RJ. Tohidi-Esfahani D, et al. Among authors: hill rj. Insect Biochem Mol Biol. 2011 Feb;41(2):77-89. doi: 10.1016/j.ibmb.2010.10.002. Epub 2010 Oct 28. Insect Biochem Mol Biol. 2011. PMID: 21035548
Synthesis, binding and bioactivity of gamma-methylene gamma-lactam ecdysone receptor ligands: advantages of QSAR models for flexible receptors.
Birru W, Fernley RT, Graham LD, Grusovin J, Hill RJ, Hofmann A, Howell L, James PJ, Jarvis KE, Johnson WM, Jones DA, Leitner C, Liepa AJ, Lovrecz GO, Lu L, Nearn RH, O'Driscoll BJ, Phan T, Pollard M, Turner KA, Winkler DA. Birru W, et al. Among authors: hill rj. Bioorg Med Chem. 2010 Aug 1;18(15):5647-60. doi: 10.1016/j.bmc.2010.06.020. Epub 2010 Jun 15. Bioorg Med Chem. 2010. PMID: 20619664
Purification and characterization of recombinant ligand-binding domains from the ecdysone receptors of four pest insects.
Graham LD, Pilling PA, Eaton RE, Gorman JJ, Braybrook C, Hannan GN, Pawlak-Skrzecz A, Noyce L, Lovrecz GO, Lu L, Hill RJ. Graham LD, et al. Among authors: hill rj. Protein Expr Purif. 2007 Jun;53(2):309-24. doi: 10.1016/j.pep.2006.12.011. Epub 2006 Dec 24. Protein Expr Purif. 2007. PMID: 17275327
An ortholog of the ecdysone receptor protein (EcR) from the parasitic nematode Haemonchus contortus.
Graham LD, Kotze AC, Fernley RT, Hill RJ. Graham LD, et al. Among authors: hill rj. Mol Biochem Parasitol. 2010 Jun;171(2):104-7. doi: 10.1016/j.molbiopara.2010.03.003. Epub 2010 Mar 10. Mol Biochem Parasitol. 2010. PMID: 20226216
Genetic Evidence for Function of the bHLH-PAS Protein Gce/Met As a Juvenile Hormone Receptor.
Jindra M, Uhlirova M, Charles JP, Smykal V, Hill RJ. Jindra M, et al. Among authors: hill rj. PLoS Genet. 2015 Jul 10;11(7):e1005394. doi: 10.1371/journal.pgen.1005394. eCollection 2015 Jul. PLoS Genet. 2015. PMID: 26161662 Free PMC article.
LcUSP, an ultraspiracle gene from the sheep blowfly, Lucilia cuprina: cDNA cloning, developmental expression of RNA and confirmation of function.
Hannan GN, Hill RJ. Hannan GN, et al. Among authors: hill rj. Insect Biochem Mol Biol. 2001 Jun 22;31(8):771-81. doi: 10.1016/s0965-1748(00)00182-x. Insect Biochem Mol Biol. 2001. PMID: 11378412
Cloning and characterization of LcEcR: a functional ecdysone receptor from the sheep blowfly Lucilia cuprina.
Hannan GN, Hill RJ. Hannan GN, et al. Among authors: hill rj. Insect Biochem Mol Biol. 1997 Jun;27(6):479-88. doi: 10.1016/s0965-1748(97)00019-2. Insect Biochem Mol Biol. 1997. PMID: 9304790
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