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Epinephrine improves 24-hour survival in a swine model of prolonged ventricular fibrillation demonstrating that early intraosseous is superior to delayed intravenous administration.

Zuercher M, Kern KB, Indik JH, Loedl M, Hilwig RW, Ummenhofer W, Berg RA, Ewy GA. Zuercher M, et al. Among authors: hilwig rw. Anesth Analg. 2011 Apr;112(4):884-90. doi: 10.1213/ANE.0b013e31820dc9ec. Epub 2011 Mar 8. Anesth Analg. 2011. PMID: 21385987

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Gasping during cardiac arrest in humans is frequent and associated with improved survival.

Bobrow BJ, Zuercher M, Ewy GA, Clark L, Chikani V, Donahue D, Sanders AB, Hilwig RW, Berg RA, Kern KB. Bobrow BJ, et al. Among authors: hilwig rw. Circulation. 2008 Dec 9;118(24):2550-4. doi: 10.1161/CIRCULATIONAHA.108.799940. Epub 2008 Nov 24. Circulation. 2008. PMID: 19029463 Free PMC article.

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Passive oxygen insufflation is superior to bag-valve-mask ventilation for witnessed ventricular fibrillation out-of-hospital cardiac arrest.

Bobrow BJ, Ewy GA, Clark L, Chikani V, Berg RA, Sanders AB, Vadeboncoeur TF, Hilwig RW, Kern KB. Bobrow BJ, et al. Among authors: hilwig rw. Ann Emerg Med. 2009 Nov;54(5):656-662.e1. doi: 10.1016/j.annemergmed.2009.06.011. Epub 2009 Aug 6. Ann Emerg Med. 2009. PMID: 19660833

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Inhibition of nitric oxide synthases, but not inducible nitric oxide synthase, selectively worsens left ventricular function after successful resuscitation from cardiac arrest in swine.

Dokken BB, Gaballa MA, Hilwig RW, Berg RA, Kern KB. Dokken BB, et al. Among authors: hilwig rw. Acad Emerg Med. 2015 Feb;22(2):197-203. doi: 10.1111/acem.12575. Epub 2015 Jan 29. Acad Emerg Med. 2015. PMID: 25639298 Free article.

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Glucagon-like peptide-1 preserves coronary microvascular endothelial function after cardiac arrest and resuscitation: potential antioxidant effects.

Dokken BB, Piermarini CV, Teachey MK, Gura MT, Dameff CJ, Heller BD, Krate J, Ashgar AM, Querin L, Mitchell JL, Hilwig RW, Kern KB. Dokken BB, et al. Among authors: hilwig rw. Am J Physiol Heart Circ Physiol. 2013 Feb 15;304(4):H538-46. doi: 10.1152/ajpheart.00282.2012. Epub 2012 Dec 15. Am J Physiol Heart Circ Physiol. 2013. PMID: 23241323 Free article.

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A sternal accelerometer does not impair hemodynamics during piglet CPR.

Zuercher M, Hilwig RW, Gura M, Nysaether J, Nadkarni VM, Berg MD, Kern KB, Berg RA. Zuercher M, et al. Among authors: hilwig rw. Resuscitation. 2011 Sep;82(9):1231-4. doi: 10.1016/j.resuscitation.2011.04.015. Epub 2011 May 5. Resuscitation. 2011. PMID: 21632167

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Utility of the ventricular fibrillation waveform to predict a return of spontaneous circulation and distinguish acute from post myocardial infarction or normal Swine in ventricular fibrillation cardiac arrest.

Indik JH, Allen D, Gura M, Dameff C, Hilwig RW, Kern KB. Indik JH, et al. Among authors: hilwig rw. Circ Arrhythm Electrophysiol. 2011 Jun;4(3):337-43. doi: 10.1161/CIRCEP.110.960419. Epub 2011 Apr 14. Circ Arrhythm Electrophysiol. 2011. PMID: 21493961

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Mild hypothermia delays the development of stone heart from untreated sustained ventricular fibrillation--a cardiovascular magnetic resonance study.

Sorrell VL, Paleru V, Altbach MI, Hilwig RW, Kern KB, Gaballa M, Ewy GA, Berg RA. Sorrell VL, et al. Among authors: hilwig rw. J Cardiovasc Magn Reson. 2011 Mar 6;13(1):17. doi: 10.1186/1532-429X-13-17. J Cardiovasc Magn Reson. 2011. PMID: 21375776 Free PMC article.

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Predictors of resuscitation in a swine model of ischemic and nonischemic ventricular fibrillation cardiac arrest: superiority of amplitude spectral area and slope to predict a return of spontaneous circulation when resuscitation efforts are prolonged.

Indik JH, Allen D, Shanmugasundaram M, Zuercher M, Hilwig RW, Berg RA, Kern KB. Indik JH, et al. Among authors: hilwig rw. Crit Care Med. 2010 Dec;38(12):2352-7. doi: 10.1097/CCM.0b013e3181fa01ee. Crit Care Med. 2010. PMID: 20890198

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Continued breathing followed by gasping or apnea in a swine model of ventricular fibrillation cardiac arrest.

Zuercher M, Ewy GA, Hilwig RW, Sanders AB, Otto CW, Berg RA, Kern KB. Zuercher M, et al. Among authors: hilwig rw. BMC Cardiovasc Disord. 2010 Aug 9;10:36. doi: 10.1186/1471-2261-10-36. BMC Cardiovasc Disord. 2010. PMID: 20691123 Free PMC article.

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