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Structural insight into an evolutionarily ancient programmed cell death regulator - the crystal structure of marine sponge BHP2 bound to LB-Bak-2.
Caria S, Hinds MG, Kvansakul M. Caria S, et al. Among authors: hinds mg. Cell Death Dis. 2017 Jan 12;8(1):e2543. doi: 10.1038/cddis.2016.469. Cell Death Dis. 2017. PMID: 28079890 Free PMC article.
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis.
Barnham KJ, McKinstry WJ, Multhaup G, Galatis D, Morton CJ, Curtain CC, Williamson NA, White AR, Hinds MG, Norton RS, Beyreuther K, Masters CL, Parker MW, Cappai R. Barnham KJ, et al. Among authors: hinds mg. J Biol Chem. 2003 May 9;278(19):17401-7. doi: 10.1074/jbc.M300629200. Epub 2003 Feb 28. J Biol Chem. 2003. PMID: 12611883
The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity.
Hinds MG, Lackmann M, Skea GL, Harrison PJ, Huang DC, Day CL. Hinds MG, et al. EMBO J. 2003 Apr 1;22(7):1497-507. doi: 10.1093/emboj/cdg144. EMBO J. 2003. PMID: 12660157 Free PMC article.
Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity.
Wilson-Annan J, O'Reilly LA, Crawford SA, Hausmann G, Beaumont JG, Parma LP, Chen L, Lackmann M, Lithgow T, Hinds MG, Day CL, Adams JM, Huang DC. Wilson-Annan J, et al. Among authors: hinds mg. J Cell Biol. 2003 Sep 1;162(5):877-87. doi: 10.1083/jcb.200302144. J Cell Biol. 2003. PMID: 12952938 Free PMC article.
The Bcl-2-regulated apoptotic pathway.
Willis S, Day CL, Hinds MG, Huang DC. Willis S, et al. Among authors: hinds mg. J Cell Sci. 2003 Oct 15;116(Pt 20):4053-6. doi: 10.1242/jcs.00754. J Cell Sci. 2003. PMID: 12972498 Review. No abstract available.
Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands.
Day CL, Puthalakath H, Skea G, Strasser A, Barsukov I, Lian LY, Huang DC, Hinds MG. Day CL, et al. Among authors: hinds mg. Biochem J. 2004 Feb 1;377(Pt 3):597-605. doi: 10.1042/BJ20031251. Biochem J. 2004. PMID: 14561217 Free PMC article.
Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands.
Day CL, Chen L, Richardson SJ, Harrison PJ, Huang DC, Hinds MG. Day CL, et al. Among authors: hinds mg. J Biol Chem. 2005 Feb 11;280(6):4738-44. doi: 10.1074/jbc.M411434200. Epub 2004 Nov 18. J Biol Chem. 2005. PMID: 15550399
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.
Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL, Adams JM, Huang DC. Chen L, et al. Among authors: hinds mg. Mol Cell. 2005 Feb 4;17(3):393-403. doi: 10.1016/j.molcel.2004.12.030. Mol Cell. 2005. PMID: 15694340
Regulation of apoptosis: uncovering the binding determinants.
Hinds MG, Day CL. Hinds MG, et al. Curr Opin Struct Biol. 2005 Dec;15(6):690-9. doi: 10.1016/j.sbi.2005.10.003. Epub 2005 Nov 2. Curr Opin Struct Biol. 2005. PMID: 16263267 Review.
Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets.
Hinds MG, Smits C, Fredericks-Short R, Risk JM, Bailey M, Huang DC, Day CL. Hinds MG, et al. Cell Death Differ. 2007 Jan;14(1):128-36. doi: 10.1038/sj.cdd.4401934. Epub 2006 Apr 28. Cell Death Differ. 2007. PMID: 16645638
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