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127 results
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Ontogeny of human hepatic cytochromes P450.
Hines RN. Hines RN. J Biochem Mol Toxicol. 2007;21(4):169-75. doi: 10.1002/jbt.20179. J Biochem Mol Toxicol. 2007. PMID: 17936930 Review.
Immunochemical and molecular biological studies on human placental cigarette smoke-inducible cytochrome P-450-dependent monooxygenase activities.
Pasanen M, Haaparanta T, Sundin M, Sivonen P, Vakakangas K, Raunio H, Hines R, Gustafsson JA, Pelkonen O. Pasanen M, et al. Toxicology. 1990 May 31;62(2):175-87. doi: 10.1016/0300-483x(90)90108-s. Toxicology. 1990. PMID: 1693794
Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene.
Nong A, McCarver DG, Hines RN, Krishnan K. Nong A, et al. Among authors: hines rn. Toxicol Appl Pharmacol. 2006 Jul 1;214(1):78-87. doi: 10.1016/j.taap.2005.12.001. Epub 2006 Feb 7. Toxicol Appl Pharmacol. 2006. PMID: 16464483
Genotyping and site-directed mutagenesis of a cytochrome P450 meander Pro-X-Arg motif critical to CYP4B1 catalysis.
Zheng YM, Henne KR, Charmley P, Kim RB, McCarver DG, Cabacungan ET, Hines RN, Rettie AE. Zheng YM, et al. Among authors: hines rn. Toxicol Appl Pharmacol. 2003 Jan 15;186(2):119-26. doi: 10.1016/s0041-008x(02)00028-5. Toxicol Appl Pharmacol. 2003. PMID: 12639503
Developmental expression of human hepatic CYP2C9 and CYP2C19.
Koukouritaki SB, Manro JR, Marsh SA, Stevens JC, Rettie AE, McCarver DG, Hines RN. Koukouritaki SB, et al. Among authors: hines rn. J Pharmacol Exp Ther. 2004 Mar;308(3):965-74. doi: 10.1124/jpet.103.060137. Epub 2003 Nov 21. J Pharmacol Exp Ther. 2004. PMID: 14634042
Human hepatic UGT2B15 developmental expression.
Divakaran K, Hines RN, McCarver DG. Divakaran K, et al. Among authors: hines rn. Toxicol Sci. 2014 Sep;141(1):292-9. doi: 10.1093/toxsci/kfu126. Epub 2014 Jun 30. Toxicol Sci. 2014. PMID: 24980262 Free PMC article.
Human hepatic CYP2B6 developmental expression: the impact of age and genotype.
Croom EL, Stevens JC, Hines RN, Wallace AD, Hodgson E. Croom EL, et al. Among authors: hines rn. Biochem Pharmacol. 2009 Jul 15;78(2):184-90. doi: 10.1016/j.bcp.2009.03.029. Epub 2009 Apr 5. Biochem Pharmacol. 2009. PMID: 19464434
Ontogeny of plasma proteins, albumin and binding of diazepam, cyclosporine, and deltamethrin.
Sethi PK, White CA, Cummings BS, Hines RN, Muralidhara S, Bruckner JV. Sethi PK, et al. Among authors: hines rn. Pediatr Res. 2016 Mar;79(3):409-15. doi: 10.1038/pr.2015.237. Epub 2015 Nov 16. Pediatr Res. 2016. PMID: 26571224
Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny.
Hines RN, Simpson PM, McCarver DG. Hines RN, et al. Drug Metab Dispos. 2016 Jul;44(7):959-66. doi: 10.1124/dmd.115.068957. Epub 2016 Jan 29. Drug Metab Dispos. 2016. PMID: 26825642
Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages.
Song G, Sun X, Hines RN, McCarver DG, Lake BG, Osimitz TG, Creek MR, Clewell HJ, Yoon M. Song G, et al. Among authors: hines rn. Drug Metab Dispos. 2017 May;45(5):468-475. doi: 10.1124/dmd.116.074583. Epub 2017 Feb 22. Drug Metab Dispos. 2017. PMID: 28228413
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