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Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice.
Winner B, Melrose HL, Zhao C, Hinkle KM, Yue M, Kent C, Braithwaite AT, Ogholikhan S, Aigner R, Winkler J, Farrer MJ, Gage FH. Winner B, et al. Among authors: hinkle km. Neurobiol Dis. 2011 Mar;41(3):706-16. doi: 10.1016/j.nbd.2010.12.008. Epub 2010 Dec 16. Neurobiol Dis. 2011. PMID: 21168496 Free PMC article.
Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice.
Melrose HL, Dächsel JC, Behrouz B, Lincoln SJ, Yue M, Hinkle KM, Kent CB, Korvatska E, Taylor JP, Witten L, Liang YQ, Beevers JE, Boules M, Dugger BN, Serna VA, Gaukhman A, Yu X, Castanedes-Casey M, Braithwaite AT, Ogholikhan S, Yu N, Bass D, Tyndall G, Schellenberg GD, Dickson DW, Janus C, Farrer MJ. Melrose HL, et al. Among authors: hinkle km. Neurobiol Dis. 2010 Dec;40(3):503-17. doi: 10.1016/j.nbd.2010.07.010. Epub 2010 Jul 24. Neurobiol Dis. 2010. PMID: 20659558 Free PMC article.
Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice.
Yue M, Hinkle KM, Davies P, Trushina E, Fiesel FC, Christenson TA, Schroeder AS, Zhang L, Bowles E, Behrouz B, Lincoln SJ, Beevers JE, Milnerwood AJ, Kurti A, McLean PJ, Fryer JD, Springer W, Dickson DW, Farrer MJ, Melrose HL. Yue M, et al. Among authors: hinkle km. Neurobiol Dis. 2015 Jun;78:172-95. doi: 10.1016/j.nbd.2015.02.031. Epub 2015 Mar 31. Neurobiol Dis. 2015. PMID: 25836420 Free PMC article.
A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease.
Melrose HL, Kent CB, Taylor JP, Dachsel JC, Hinkle KM, Lincoln SJ, Mok SS, Culvenor JG, Masters CL, Tyndall GM, Bass DI, Ahmed Z, Andorfer CA, Ross OA, Wszolek ZK, Delldonne A, Dickson DW, Farrer MJ. Melrose HL, et al. Among authors: hinkle km. Neuroscience. 2007 Jul 29;147(4):1047-58. doi: 10.1016/j.neuroscience.2007.05.027. Epub 2007 Jul 3. Neuroscience. 2007. PMID: 17611037
Identification of potential protein interactors of Lrrk2.
Dächsel JC, Taylor JP, Mok SS, Ross OA, Hinkle KM, Bailey RM, Hines JH, Szutu J, Madden B, Petrucelli L, Farrer MJ. Dächsel JC, et al. Among authors: hinkle km. Parkinsonism Relat Disord. 2007 Oct;13(7):382-5. doi: 10.1016/j.parkreldis.2007.01.008. Epub 2007 Apr 2. Parkinsonism Relat Disord. 2007. PMID: 17400507 Free PMC article.
24 results