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Generation of novel pharmacogenomic candidates in response to methotrexate in juvenile idiopathic arthritis: correlation between gene expression and genotype.
Moncrieffe H, Hinks A, Ursu S, Kassoumeri L, Etheridge A, Hubank M, Martin P, Weiler T, Glass DN, Thompson SD, Thomson W, Wedderburn LR. Moncrieffe H, et al. Among authors: hinks a. Pharmacogenet Genomics. 2010 Nov;20(11):665-76. doi: 10.1097/FPC.0b013e32833f2cd0. Pharmacogenet Genomics. 2010. PMID: 20827233 Free PMC article.
Association of the IL-10 gene family locus on chromosome 1 with juvenile idiopathic arthritis (JIA).
Omoyinmi E, Forabosco P, Hamaoui R, Bryant A, Hinks A, Ursu S; Childhood Arthritis Prospective Study (CAPS); BSPAR study group; Childhood Arthritis Response to Medication Study (CHARMS); Wedderburn LR, Thomson W, Lewis CM, Woo P. Omoyinmi E, et al. Among authors: hinks a. PLoS One. 2012;7(10):e47673. doi: 10.1371/journal.pone.0047673. Epub 2012 Oct 18. PLoS One. 2012. PMID: 23094074 Free PMC article.
Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
Cobb J, Cule E, Moncrieffe H, Hinks A, Ursu S, Patrick F, Kassoumeri L, Flynn E, Bulatović M, Wulffraat N, van Zelst B, de Jonge R, Bohm M, Dolezalova P, Hirani S, Newman S, Whitworth P, Southwood TR, De Iorio M; Childhood Arthritis Response to Medication Study (CHARMS); Childhood Arthritis Prospective Study (CAPS); BSPAR study group; Wedderburn LR, Thomson W. Cobb J, et al. Among authors: hinks a. Pharmacogenomics J. 2014 Aug;14(4):356-64. doi: 10.1038/tpj.2014.3. Epub 2014 Apr 8. Pharmacogenomics J. 2014. PMID: 24709693 Free PMC article.
HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis.
Ombrello MJ, Remmers EF, Tachmazidou I, Grom A, Foell D, Haas JP, Martini A, Gattorno M, Özen S, Prahalad S, Zeft AS, Bohnsack JF, Mellins ED, Ilowite NT, Russo R, Len C, Hilario MO, Oliveira S, Yeung RS, Rosenberg A, Wedderburn LR, Anton J, Schwarz T, Hinks A, Bilginer Y, Park J, Cobb J, Satorius CL, Han B, Baskin E, Signa S, Duerr RH, Achkar JP, Kamboh MI, Kaufman KM, Kottyan LC, Pinto D, Scherer SW, Alarcón-Riquelme ME, Docampo E, Estivill X, Gül A; British Society of Pediatric and Adolescent Rheumatology (BSPAR) Study Group; Childhood Arthritis Prospective Study (CAPS) Group; Randomized Placebo Phase Study of Rilonacept in sJIA (RAPPORT) Investigators; Sparks-Childhood Arthritis Response to Medication Study (CHARMS) Group; Biologically Based Outcome Predictors in JIA (BBOP) Group; de Bakker PI, Raychaudhuri S, Langefeld CD, Thompson S, Zeggini E, Thomson W, Kastner DL, Woo P; International Childhood Arthritis Genetics (INCHARGE) Consortium. Ombrello MJ, et al. Among authors: hinks a. Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):15970-5. doi: 10.1073/pnas.1520779112. Epub 2015 Nov 23. Proc Natl Acad Sci U S A. 2015. PMID: 26598658 Free PMC article.
Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis.
Hinks A, Ke X, Barton A, Eyre S, Bowes J, Worthington J, Thompson SD, Langefeld CD, Glass DN, Thomson W; UK Rheumatoid Arthritis Genetics Consortium; British Society of Paediatric and Adolescent Rheumatology Study Group. Hinks A, et al. Arthritis Rheum. 2009 Jan;60(1):251-7. doi: 10.1002/art.24187. Arthritis Rheum. 2009. PMID: 19116909 Free PMC article.
Association of the CCR5 gene with juvenile idiopathic arthritis.
Hinks A, Martin P, Flynn E, Eyre S, Packham J; Childhood Arthritis Prospective Study (CAPS), UKRAG Consortium, BSPAR Study Group; Barton A, Worthington J, Thomson W. Hinks A, et al. Genes Immun. 2010 Oct;11(7):584-9. doi: 10.1038/gene.2010.25. Epub 2010 May 13. Genes Immun. 2010. PMID: 20463745 Free PMC article.
109 results