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Exploiting the curative potential of adoptive T-cell therapy for cancer.
Hinrichs CS, Rosenberg SA. Hinrichs CS, et al. Immunol Rev. 2014 Jan;257(1):56-71. doi: 10.1111/imr.12132. Immunol Rev. 2014. PMID: 24329789 Free PMC article. Review.
Bedside to bench and back again: how animal models are guiding the development of new immunotherapies for cancer.
Finkelstein SE, Heimann DM, Klebanoff CA, Antony PA, Gattinoni L, Hinrichs CS, Hwang LN, Palmer DC, Spiess PJ, Surman DR, Wrzesiniski C, Yu Z, Rosenberg SA, Restifo NP. Finkelstein SE, et al. Among authors: hinrichs cs. J Leukoc Biol. 2004 Aug;76(2):333-7. doi: 10.1189/jlb.0304120. Epub 2004 May 20. J Leukoc Biol. 2004. PMID: 15155774 Free PMC article.
Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.
Zeng R, Spolski R, Finkelstein SE, Oh S, Kovanen PE, Hinrichs CS, Pise-Masison CA, Radonovich MF, Brady JN, Restifo NP, Berzofsky JA, Leonard WJ. Zeng R, et al. Among authors: hinrichs cs. J Exp Med. 2005 Jan 3;201(1):139-48. doi: 10.1084/jem.20041057. J Exp Med. 2005. PMID: 15630141 Free PMC article.
Glucocorticoids do not inhibit antitumor activity of activated CD8+ T cells.
Hinrichs CS, Palmer DC, Rosenberg SA, Restifo NP. Hinrichs CS, et al. J Immunother. 2005 Nov-Dec;28(6):517-24. doi: 10.1097/01.cji.0000177999.95831.7b. J Immunother. 2005. PMID: 16224268 Free PMC article.
Programming CD8+ T cells for effective immunotherapy.
Hinrichs CS, Gattinoni L, Restifo NP. Hinrichs CS, et al. Curr Opin Immunol. 2006 Jun;18(3):363-70. doi: 10.1016/j.coi.2006.03.009. Epub 2006 Apr 17. Curr Opin Immunol. 2006. PMID: 16616471 Free PMC article. Review.
Interleukin-2-dependent mechanisms of tolerance and immunity in vivo.
Antony PA, Paulos CM, Ahmadzadeh M, Akpinarli A, Palmer DC, Sato N, Kaiser A, Hinrichs CS, Klebanoff CA, Tagaya Y, Restifo NP. Antony PA, et al. Among authors: hinrichs cs. J Immunol. 2006 May 1;176(9):5255-66. doi: 10.4049/jimmunol.176.9.5255. J Immunol. 2006. PMID: 16621991 Free PMC article.
Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling.
Paulos CM, Wrzesinski C, Kaiser A, Hinrichs CS, Chieppa M, Cassard L, Palmer DC, Boni A, Muranski P, Yu Z, Gattinoni L, Antony PA, Rosenberg SA, Restifo NP. Paulos CM, et al. Among authors: hinrichs cs. J Clin Invest. 2007 Aug;117(8):2197-204. doi: 10.1172/JCI32205. J Clin Invest. 2007. PMID: 17657310 Free PMC article.
Toll-like receptors in tumor immunotherapy.
Paulos CM, Kaiser A, Wrzesinski C, Hinrichs CS, Cassard L, Boni A, Muranski P, Sanchez-Perez L, Palmer DC, Yu Z, Antony PA, Gattinoni L, Rosenberg SA, Restifo NP. Paulos CM, et al. Among authors: hinrichs cs. Clin Cancer Res. 2007 Sep 15;13(18 Pt 1):5280-9. doi: 10.1158/1078-0432.CCR-07-1378. Clin Cancer Res. 2007. PMID: 17875756 Free PMC article. Review.
IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy.
Hinrichs CS, Spolski R, Paulos CM, Gattinoni L, Kerstann KW, Palmer DC, Klebanoff CA, Rosenberg SA, Leonard WJ, Restifo NP. Hinrichs CS, et al. Blood. 2008 Jun 1;111(11):5326-33. doi: 10.1182/blood-2007-09-113050. Epub 2008 Feb 14. Blood. 2008. PMID: 18276844 Free PMC article.
Tumor-specific Th17-polarized cells eradicate large established melanoma.
Muranski P, Boni A, Antony PA, Cassard L, Irvine KR, Kaiser A, Paulos CM, Palmer DC, Touloukian CE, Ptak K, Gattinoni L, Wrzesinski C, Hinrichs CS, Kerstann KW, Feigenbaum L, Chan CC, Restifo NP. Muranski P, et al. Among authors: hinrichs cs. Blood. 2008 Jul 15;112(2):362-73. doi: 10.1182/blood-2007-11-120998. Epub 2008 Mar 19. Blood. 2008. PMID: 18354038 Free PMC article.
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