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A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration.
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin CM, Mitra D, Zhu D, Thomas BB, Hikita ST, Pennington BO, Johnson LV, Clegg DO, Hinton DR, Humayun MS. Kashani AH, et al. Among authors: hinton dr. Sci Transl Med. 2018 Apr 4;10(435):eaao4097. doi: 10.1126/scitranslmed.aao4097. Sci Transl Med. 2018. PMID: 29618560 Clinical Trial.
Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer.
Diniz B, Thomas P, Thomas B, Ribeiro R, Hu Y, Brant R, Ahuja A, Zhu D, Liu L, Koss M, Maia M, Chader G, Hinton DR, Humayun MS. Diniz B, et al. Among authors: hinton dr. Invest Ophthalmol Vis Sci. 2013 Jul 26;54(7):5087-96. doi: 10.1167/iovs.12-11239. Invest Ophthalmol Vis Sci. 2013. PMID: 23833067 Free PMC article.
Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs.
Koss MJ, Falabella P, Stefanini FR, Pfister M, Thomas BB, Kashani AH, Brant R, Zhu D, Clegg DO, Hinton DR, Humayun MS. Koss MJ, et al. Among authors: hinton dr. Graefes Arch Clin Exp Ophthalmol. 2016 Aug;254(8):1553-1565. doi: 10.1007/s00417-016-3386-y. Epub 2016 Jun 22. Graefes Arch Clin Exp Ophthalmol. 2016. PMID: 27335025
Surgical Method for Implantation of a Biosynthetic Retinal Pigment Epithelium Monolayer for Geographic Atrophy: Experience from a Phase 1/2a Study.
Kashani AH, Uang J, Mert M, Rahhal F, Chan C, Avery RL, Dugel P, Chen S, Lebkowski J, Clegg DO, Hinton DR, Humayun MS. Kashani AH, et al. Among authors: hinton dr. Ophthalmol Retina. 2020 Mar;4(3):264-273. doi: 10.1016/j.oret.2019.09.017. Epub 2019 Oct 7. Ophthalmol Retina. 2020. PMID: 31786135 Clinical Trial.
Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.
Pennington BO, Bailey JK, Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D, Martinez-Camarillo JC, Lin TC, Thomas BB, Hinton DR, Humayun MS, Lebkowski J, Johnson LV, Clegg DO. Pennington BO, et al. Among authors: hinton dr. Sci Rep. 2021 Mar 18;11(1):6286. doi: 10.1038/s41598-021-85631-6. Sci Rep. 2021. PMID: 33737600 Free PMC article.
368 results