Hinz S - Search Results

1

Selectivity is species-dependent: Characterization of standard agonists and antagonists at human, rat, and mouse adenosine receptors.

Alnouri MW, Jepards S, Casari A, Schiedel AC, Hinz S, Müller CE. Alnouri MW, et al. Among authors: hinz s. Purinergic Signal. 2015 Sep;11(3):389-407. doi: 10.1007/s11302-015-9460-9. Epub 2015 Jul 1. Purinergic Signal. 2015. PMID: 26126429 Free PMC article.

2

Improving potency, selectivity, and water solubility of adenosine A1 receptor antagonists: xanthines modified at position 3 and related pyrimido[1,2,3-cd]purinediones.

Weyler S, Fülle F, Diekmann M, Schumacher B, Hinz S, Klotz KN, Müller CE. Weyler S, et al. Among authors: hinz s. ChemMedChem. 2006 Aug;1(8):891-902. doi: 10.1002/cmdc.200600066. ChemMedChem. 2006. PMID: 16902942

3

Synthesis and pharmacological evaluation of coumarin derivatives as cannabinoid receptor antagonists and inverse agonists.

Behrenswerth A, Volz N, Toräng J, Hinz S, Bräse S, Müller CE. Behrenswerth A, et al. Among authors: hinz s. Bioorg Med Chem. 2009 Apr 1;17(7):2842-51. doi: 10.1016/j.bmc.2009.02.027. Epub 2009 Feb 21. Bioorg Med Chem. 2009. PMID: 19278853

4

1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity.

Borrmann T, Hinz S, Bertarelli DC, Li W, Florin NC, Scheiff AB, Müller CE. Borrmann T, et al. Among authors: hinz s. J Med Chem. 2009 Jul 9;52(13):3994-4006. doi: 10.1021/jm900413e. J Med Chem. 2009. PMID: 19569717

5

The four cysteine residues in the second extracellular loop of the human adenosine A2B receptor: role in ligand binding and receptor function.

Schiedel AC, Hinz S, Thimm D, Sherbiny F, Borrmann T, Maass A, Müller CE. Schiedel AC, et al. Among authors: hinz s. Biochem Pharmacol. 2011 Aug 15;82(4):389-99. doi: 10.1016/j.bcp.2011.05.008. Epub 2011 May 18. Biochem Pharmacol. 2011. PMID: 21620804

6

7-Alkyl-3-benzylcoumarins: a versatile scaffold for the development of potent and selective cannabinoid receptor agonists and antagonists.

Rempel V, Volz N, Hinz S, Karcz T, Meliciani I, Nieger M, Wenzel W, Bräse S, Müller CE. Rempel V, et al. Among authors: hinz s. J Med Chem. 2012 Sep 27;55(18):7967-77. doi: 10.1021/jm3008213. Epub 2012 Sep 11. J Med Chem. 2012. PMID: 22916707

7

Ligand-specific binding and activation of the human adenosine A(2B) receptor.

Thimm D, Schiedel AC, Sherbiny FF, Hinz S, Hochheiser K, Bertarelli DC, Maass A, Müller CE. Thimm D, et al. Among authors: hinz s. Biochemistry. 2013 Jan 29;52(4):726-40. doi: 10.1021/bi3012065. Epub 2013 Jan 14. Biochemistry. 2013. PMID: 23286920

8

The second extracellular loop of GPCRs determines subtype-selectivity and controls efficacy as evidenced by loop exchange study at A2 adenosine receptors.

Seibt BF, Schiedel AC, Thimm D, Hinz S, Sherbiny FF, Müller CE. Seibt BF, et al. Among authors: hinz s. Biochem Pharmacol. 2013 May 1;85(9):1317-29. doi: 10.1016/j.bcp.2013.03.005. Epub 2013 Mar 13. Biochem Pharmacol. 2013. PMID: 23500543

9

Dual targeting of adenosine A(2A) receptors and monoamine oxidase B by 4H-3,1-benzothiazin-4-ones.

Stössel A, Schlenk M, Hinz S, Küppers P, Heer J, Gütschow M, Müller CE. Stössel A, et al. Among authors: hinz s. J Med Chem. 2013 Jun 13;56(11):4580-96. doi: 10.1021/jm400336x. Epub 2013 May 30. J Med Chem. 2013. PMID: 23631427

10

Carbamazepine derivatives with P2X4 receptor-blocking activity.

Tian M, Abdelrahman A, Weinhausen S, Hinz S, Weyer S, Dosa S, El-Tayeb A, Müller CE. Tian M, et al. Among authors: hinz s. Bioorg Med Chem. 2014 Feb 1;22(3):1077-88. doi: 10.1016/j.bmc.2013.12.035. Epub 2013 Dec 25. Bioorg Med Chem. 2014. PMID: 24411477

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