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1,633 results
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Type 1 metabotropic glutamate receptor and its signaling molecules as therapeutic targets for the treatment of cerebellar disorders.
Hirai H, Kano M. Hirai H, et al. Curr Opin Pharmacol. 2018 Feb;38:51-58. doi: 10.1016/j.coph.2018.02.002. Epub 2018 Mar 8. Curr Opin Pharmacol. 2018. PMID: 29525719 Review.
New role of delta2-glutamate receptors in AMPA receptor trafficking and cerebellar function.
Hirai H, Launey T, Mikawa S, Torashima T, Yanagihara D, Kasaura T, Miyamoto A, Yuzaki M. Hirai H, et al. Nat Neurosci. 2003 Aug;6(8):869-76. doi: 10.1038/nn1086. Nat Neurosci. 2003. PMID: 12833050
In vivo transduction of murine cerebellar Purkinje cells by HIV-derived lentiviral vectors.
Torashima T, Okoyama S, Nishizaki T, Hirai H. Torashima T, et al. Among authors: hirai h. Brain Res. 2006 Apr 12;1082(1):11-22. doi: 10.1016/j.brainres.2006.01.104. Epub 2006 Mar 6. Brain Res. 2006. PMID: 16516872
Inositol 1,4,5-trisphosphate receptor type 1 in granule cells, not in Purkinje cells, regulates the dendritic morphology of Purkinje cells through brain-derived neurotrophic factor production.
Hisatsune C, Kuroda Y, Akagi T, Torashima T, Hirai H, Hashikawa T, Inoue T, Mikoshiba K. Hisatsune C, et al. Among authors: hirai h. J Neurosci. 2006 Oct 18;26(42):10916-24. doi: 10.1523/JNEUROSCI.3269-06.2006. J Neurosci. 2006. PMID: 17050730 Free PMC article.
Ca2+ permeability of the channel pore is not essential for the delta2 glutamate receptor to regulate synaptic plasticity and motor coordination.
Kakegawa W, Miyazaki T, Hirai H, Motohashi J, Mishina M, Watanabe M, Yuzaki M. Kakegawa W, et al. Among authors: hirai h. J Physiol. 2007 Mar 15;579(Pt 3):729-35. doi: 10.1113/jphysiol.2006.127100. Epub 2007 Jan 25. J Physiol. 2007. PMID: 17255161 Free PMC article.
CD3 and immunoglobulin G Fc receptor regulate cerebellar functions.
Nakamura K, Hirai H, Torashima T, Miyazaki T, Tsurui H, Xiu Y, Ohtsuji M, Lin QS, Tsukamoto K, Nishimura H, Ono M, Watanabe M, Hirose S. Nakamura K, et al. Among authors: hirai h. Mol Cell Biol. 2007 Jul;27(14):5128-34. doi: 10.1128/MCB.01072-06. Epub 2007 May 14. Mol Cell Biol. 2007. PMID: 17502348 Free PMC article.
Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia.
Torashima T, Koyama C, Iizuka A, Mitsumura K, Takayama K, Yanagi S, Oue M, Yamaguchi H, Hirai H. Torashima T, et al. Among authors: hirai h. EMBO Rep. 2008 Apr;9(4):393-9. doi: 10.1038/embor.2008.31. Epub 2008 Mar 14. EMBO Rep. 2008. PMID: 18344973 Free PMC article.
Progress in transduction of cerebellar Purkinje cells in vivo using viral vectors.
Hirai H. Hirai H. Cerebellum. 2008;7(3):273-8. doi: 10.1007/s12311-008-0012-5. Cerebellum. 2008. PMID: 18418690 Review.
Purkinje-cell-preferential transduction by lentiviral vectors with the murine stem cell virus promoter.
Takayama K, Torashima T, Horiuchi H, Hirai H. Takayama K, et al. Among authors: hirai h. Neurosci Lett. 2008 Sep 26;443(1):7-11. doi: 10.1016/j.neulet.2008.07.058. Epub 2008 Jul 25. Neurosci Lett. 2008. PMID: 18675313
Potential usefulness of D2R reporter gene imaging by IBF as gene therapy monitoring for cerebellar neurodegenerative diseases.
Shiba K, Torashima T, Hirai H, Ogawa K, Akhter N, Nakajima K, Kinuya S, Mori H. Shiba K, et al. Among authors: hirai h. J Cereb Blood Flow Metab. 2009 Feb;29(2):434-40. doi: 10.1038/jcbfm.2008.137. Epub 2008 Nov 12. J Cereb Blood Flow Metab. 2009. PMID: 19002197
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