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Structural basis of phosphatidylinositol 3-kinase C2α function.
Lo WT, Zhang Y, Vadas O, Roske Y, Gulluni F, De Santis MC, Zagar AV, Stephanowitz H, Hirsch E, Liu F, Daumke O, Kudryashev M, Haucke V. Lo WT, et al. Among authors: hirsch e. Nat Struct Mol Biol. 2022 Mar;29(3):218-228. doi: 10.1038/s41594-022-00730-w. Epub 2022 Mar 7. Nat Struct Mol Biol. 2022. PMID: 35256802 Free PMC article.
Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.
Ciraolo E, Morello F, Hobbs RM, Wolf F, Marone R, Iezzi M, Lu X, Mengozzi G, Altruda F, Sorba G, Guan K, Pandolfi PP, Wymann MP, Hirsch E. Ciraolo E, et al. Among authors: hirsch e. Mol Biol Cell. 2010 Mar 1;21(5):704-11. doi: 10.1091/mbc.e09-08-0744. Epub 2010 Jan 6. Mol Biol Cell. 2010. PMID: 20053680 Free PMC article.
PI3K kinase and scaffold functions in heart.
Damilano F, Perino A, Hirsch E. Damilano F, et al. Among authors: hirsch e. Ann N Y Acad Sci. 2010 Feb;1188:39-45. doi: 10.1111/j.1749-6632.2009.05081.x. Ann N Y Acad Sci. 2010. PMID: 20201884 Review.
Measuring PI3K lipid kinase activity.
Ciraolo E, Perino A, Hirsch E. Ciraolo E, et al. Among authors: hirsch e. Methods Mol Biol. 2012;795:55-67. doi: 10.1007/978-1-61779-337-0_4. Methods Mol Biol. 2012. PMID: 21960215
Targeting PI3K in Cancer: Any Good News?
Martini M, Ciraolo E, Gulluni F, Hirsch E. Martini M, et al. Among authors: hirsch e. Front Oncol. 2013 May 8;3:108. doi: 10.3389/fonc.2013.00108. eCollection 2013. Front Oncol. 2013. PMID: 23658859 Free PMC article.
Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate.
Posor Y, Eichhorn-Gruenig M, Puchkov D, Schöneberg J, Ullrich A, Lampe A, Müller R, Zarbakhsh S, Gulluni F, Hirsch E, Krauss M, Schultz C, Schmoranzer J, Noé F, Haucke V. Posor Y, et al. Among authors: hirsch e. Nature. 2013 Jul 11;499(7457):233-7. doi: 10.1038/nature12360. Epub 2013 Jul 3. Nature. 2013. PMID: 23823722
PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function.
Franco I, Gulluni F, Campa CC, Costa C, Margaria JP, Ciraolo E, Martini M, Monteyne D, De Luca E, Germena G, Posor Y, Maffucci T, Marengo S, Haucke V, Falasca M, Perez-Morga D, Boletta A, Merlo GR, Hirsch E. Franco I, et al. Among authors: hirsch e. Dev Cell. 2014 Mar 31;28(6):647-58. doi: 10.1016/j.devcel.2014.01.022. Dev Cell. 2014. PMID: 24697898 Free PMC article.
PI3K/AKT signaling pathway and cancer: an updated review.
Martini M, De Santis MC, Braccini L, Gulluni F, Hirsch E. Martini M, et al. Among authors: hirsch e. Ann Med. 2014 Sep;46(6):372-83. doi: 10.3109/07853890.2014.912836. Epub 2014 Jun 5. Ann Med. 2014. PMID: 24897931 Review.
Methods to measure the enzymatic activity of PI3Ks.
Ciraolo E, Gulluni F, Hirsch E. Ciraolo E, et al. Among authors: hirsch e. Methods Enzymol. 2014;543:115-40. doi: 10.1016/B978-0-12-801329-8.00006-4. Methods Enzymol. 2014. PMID: 24924130
1,541 results