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Colistin-resistant Acinetobacter baumannii: beyond carbapenem resistance.

Qureshi ZA, Hittle LE, O'Hara JA, Rivera JI, Syed A, Shields RK, Pasculle AW, Ernst RK, Doi Y. Qureshi ZA, et al. Among authors: hittle le. Clin Infect Dis. 2015 May 1;60(9):1295-303. doi: 10.1093/cid/civ048. Epub 2015 Jan 28. Clin Infect Dis. 2015. PMID: 25632010 Free PMC article.

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Little cigars and cigarillos harbor diverse bacterial communities that differ between the tobacco and the wrapper.

Chattopadhyay S, Smyth EM, Kulkarni P, Babik KR, Reid M, Hittle LE, Clark PI, Mongodin EF, Sapkota AR. Chattopadhyay S, et al. Among authors: hittle le. PLoS One. 2019 Feb 22;14(2):e0211705. doi: 10.1371/journal.pone.0211705. eCollection 2019. PLoS One. 2019. PMID: 30794551 Free PMC article.

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The Bacterial Communities of Little Cigars and Cigarillos Are Dynamic Over Time and Varying Storage Conditions.

Smyth EM, Chattopadhyay S, Babik K, Reid M, Chopyk J, Malayil L, Kulkarni P, Hittle LE, Clark PI, Sapkota AR, Mongodin EF. Smyth EM, et al. Among authors: hittle le. Front Microbiol. 2019 Oct 25;10:2371. doi: 10.3389/fmicb.2019.02371. eCollection 2019. Front Microbiol. 2019. PMID: 31708882 Free PMC article.

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Temporal instability of the post-surgical maxillary sinus microbiota.

Koutsourelakis I, Halderman A, Khalil S, Hittle LE, Mongodin EF, Lane AP. Koutsourelakis I, et al. Among authors: hittle le. BMC Infect Dis. 2018 Aug 30;18(1):441. doi: 10.1186/s12879-018-3272-9. BMC Infect Dis. 2018. PMID: 30165830 Free PMC article.

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1,2,4-Triazolidine-3-thiones Have Specific Activity against Acinetobacter baumannii among Common Nosocomial Pathogens.

Corey BW, Thompson MG, Hittle LE, Jacobs AC, Asafo-Adjei EA, Huggins WM, Melander RJ, Melander C, Ernst RK, Zurawski DV. Corey BW, et al. Among authors: hittle le. ACS Infect Dis. 2017 Jan 13;3(1):62-71. doi: 10.1021/acsinfecdis.6b00133. Epub 2016 Nov 3. ACS Infect Dis. 2017. PMID: 27764938 Free PMC article.

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Site-specific activity of the acyltransferases HtrB1 and HtrB2 in Pseudomonas aeruginosa lipid A biosynthesis.

Hittle LE, Powell DA, Jones JW, Tofigh M, Goodlett DR, Moskowitz SM, Ernst RK. Hittle LE, et al. Pathog Dis. 2015 Nov;73(8):ftv053. doi: 10.1093/femspd/ftv053. Epub 2015 Jul 29. Pathog Dis. 2015. PMID: 26223882 Free PMC article.

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Small molecule downregulation of PmrAB reverses lipid A modification and breaks colistin resistance.

Harris TL, Worthington RJ, Hittle LE, Zurawski DV, Ernst RK, Melander C. Harris TL, et al. Among authors: hittle le. ACS Chem Biol. 2014 Jan 17;9(1):122-7. doi: 10.1021/cb400490k. Epub 2013 Oct 28. ACS Chem Biol. 2014. PMID: 24131198

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Temporal Variations in Cigarette Tobacco Bacterial Community Composition and Tobacco-Specific Nitrosamine Content Are Influenced by Brand and Storage Conditions.

Chopyk J, Chattopadhyay S, Kulkarni P, Smyth EM, Hittle LE, Paulson JN, Pop M, Buehler SS, Clark PI, Mongodin EF, Sapkota AR. Chopyk J, et al. Among authors: hittle le. Front Microbiol. 2017 Mar 7;8:358. doi: 10.3389/fmicb.2017.00358. eCollection 2017. Front Microbiol. 2017. PMID: 28326071 Free PMC article.

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A Pseudomonas aeruginosa hepta-acylated lipid A variant associated with cystic fibrosis selectively activates human neutrophils.

SenGupta S, Hittle LE, Ernst RK, Uriarte SM, Mitchell TC. SenGupta S, et al. Among authors: hittle le. J Leukoc Biol. 2016 Nov;100(5):1047-1059. doi: 10.1189/jlb.4VMA0316-101R. Epub 2016 Aug 18. J Leukoc Biol. 2016. PMID: 27538572 Free PMC article.

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Mentholation affects the cigarette microbiota by selecting for bacteria resistant to harsh environmental conditions and selecting against potential bacterial pathogens.

Chopyk J, Chattopadhyay S, Kulkarni P, Claye E, Babik KR, Reid MC, Smyth EM, Hittle LE, Paulson JN, Cruz-Cano R, Pop M, Buehler SS, Clark PI, Sapkota AR, Mongodin EF. Chopyk J, et al. Among authors: hittle le. Microbiome. 2017 Feb 15;5(1):22. doi: 10.1186/s40168-017-0235-0. Microbiome. 2017. PMID: 28202080 Free PMC article.

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