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Sphingosine 1-phosphate receptors.
Hla T. Hla T. Prostaglandins Other Lipid Mediat. 2001 Apr;64(1-4):135-42. doi: 10.1016/s0090-6980(01)00109-5. Prostaglandins Other Lipid Mediat. 2001. PMID: 11324703 Review.
The mouse gene for the inducible G-protein-coupled receptor edg-1.
Liu CH, Hla T. Liu CH, et al. Among authors: hla t. Genomics. 1997 Jul 1;43(1):15-24. doi: 10.1006/geno.1997.4759. Genomics. 1997. PMID: 9226368
Edg-1, an immediate-early gene induced during the in vitro differentiation of human endothelial cells, encodes a G-protein-coupled receptor (GPR) that signals via the G(i)/mitogen-activated protein kinase (MAP kinase) pathway (Lee, M.-J., Evans, M., and Hla, T. (199 …
Edg-1, an immediate-early gene induced during the in vitro differentiation of human endothelial cells, encodes a G-protein-coupled receptor …
Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival.
Van Brocklyn JR, Lee MJ, Menzeleev R, Olivera A, Edsall L, Cuvillier O, Thomas DM, Coopman PJ, Thangada S, Liu CH, Hla T, Spiegel S. Van Brocklyn JR, et al. Among authors: hla t. J Cell Biol. 1998 Jul 13;142(1):229-40. doi: 10.1083/jcb.142.1.229. J Cell Biol. 1998. PMID: 9660876 Free PMC article.
Van Brocklyn, S. Thangada, C.H. Liu, A.R. Hand, R. Menzeleev, S. Spiegel, and T. Hla. 1998. Science. 279:1552-1555). Edg-1 binds SPP with remarkable specificity as only sphinganine-1-phosphate displaced radiolabeled SPP, while other sphingolipids did not. ...
Van Brocklyn, S. Thangada, C.H. Liu, A.R. Hand, R. Menzeleev, S. Spiegel, and T. Hla. 1998. Science. 279:1552-1555). Edg-1 bin …
Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist.
Lee MJ, Thangada S, Liu CH, Thompson BD, Hla T. Lee MJ, et al. Among authors: hla t. J Biol Chem. 1998 Aug 21;273(34):22105-12. doi: 10.1074/jbc.273.34.22105. J Biol Chem. 1998. PMID: 9705355
., Thangada, S., Liu, C. H., Hand, A. R., Menzeleev, R., Spiegel, S., and Hla, T. (1998) Science 279, 1552-1555). In this study, we show that lysophosphatidic acid (LPA), a platelet-derived bioactive lipid structurally related to SPP, is an agonist for EDG-1. ...
., Thangada, S., Liu, C. H., Hand, A. R., Menzeleev, R., Spiegel, S., and Hla, T. (1998) Science 279, 1552-1555). In this stud …
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