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Progressive brain changes in schizophrenia related to antipsychotic treatment? A meta-analysis of longitudinal MRI studies.
Fusar-Poli P, Smieskova R, Kempton MJ, Ho BC, Andreasen NC, Borgwardt S. Fusar-Poli P, et al. Neurosci Biobehav Rev. 2013 Sep;37(8):1680-91. doi: 10.1016/j.neubiorev.2013.06.001. Epub 2013 Jun 14. Neurosci Biobehav Rev. 2013. PMID: 23769814 Free PMC article.
Individual studies suggested they can significantly affect brain structure and account for progressive brain changes observed during the illness. ...At baseline, patients showed significant whole brain volume reductions and enlarged lateral ventricle (LV) vol …
Individual studies suggested they can significantly affect brain structure and account for progressive brain changes observed …
Prism adaptation in schizophrenia.
Bigelow NO, Turner BM, Andreasen NC, Paulsen JS, O'Leary DS, Ho BC. Bigelow NO, et al. Brain Cogn. 2006 Aug;61(3):235-42. doi: 10.1016/j.bandc.2006.01.004. Epub 2006 Feb 28. Brain Cogn. 2006. PMID: 16510223
Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years.
Dima D, Modabbernia A, Papachristou E, Doucet GE, Agartz I, Aghajani M, Akudjedu TN, Albajes-Eizagirre A, Alnaes D, Alpert KI, Andersson M, Andreasen NC, Andreassen OA, Asherson P, Banaschewski T, Bargallo N, Baumeister S, Baur-Streubel R, Bertolino A, Bonvino A, Boomsma DI, Borgwardt S, Bourque J, Brandeis D, Breier A, Brodaty H, Brouwer RM, Buitelaar JK, Busatto GF, Buckner RL, Calhoun V, Canales-Rodríguez EJ, Cannon DM, Caseras X, Castellanos FX, Cervenka S, Chaim-Avancini TM, Ching CRK, Chubar V, Clark VP, Conrod P, Conzelmann A, Crespo-Facorro B, Crivello F, Crone EA, Dannlowski U, Dale AM, Davey C, de Geus EJC, de Haan L, de Zubicaray GI, den Braber A, Dickie EW, Di Giorgio A, Doan NT, Dørum ES, Ehrlich S, Erk S, Espeseth T, Fatouros-Bergman H, Fisher SE, Fouche JP, Franke B, Frodl T, Fuentes-Claramonte P, Glahn DC, Gotlib IH, Grabe HJ, Grimm O, Groenewold NA, Grotegerd D, Gruber O, Gruner P, Gur RE, Gur RC, Hahn T, Harrison BJ, Hartman CA, Hatton SN, Heinz A, Heslenfeld DJ, Hibar DP, Hickie IB, Ho BC, Hoekstra PJ, Hohmann S, Holmes AJ, Hoogman M, Hosten N, Howells FM, Hulshoff Pol HE, Huyser C, Jahanshad N, James A, Jernigan TL, Jiang J, Jönsson EG, Joska JA, Kahn R, Kalnin… See abstract for full author list ➔ Dima D, et al. Hum Brain Mapp. 2022 Jan;43(1):452-469. doi: 10.1002/hbm.25320. Epub 2021 Feb 11. Hum Brain Mapp. 2022. PMID: 33570244 Free PMC article.
Age has a major effect on brain volume. However, the normative studies available are constrained by small sample sizes, restricted age coverage and significant methodological variability. These limitations introduce inconsistencies and may obscure or distort the lifespan t …
Age has a major effect on brain volume. However, the normative studies available are constrained by small sample sizes, restricted ag …
Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years.
Frangou S, Modabbernia A, Williams SCR, Papachristou E, Doucet GE, Agartz I, Aghajani M, Akudjedu TN, Albajes-Eizagirre A, Alnaes D, Alpert KI, Andersson M, Andreasen NC, Andreassen OA, Asherson P, Banaschewski T, Bargallo N, Baumeister S, Baur-Streubel R, Bertolino A, Bonvino A, Boomsma DI, Borgwardt S, Bourque J, Brandeis D, Breier A, Brodaty H, Brouwer RM, Buitelaar JK, Busatto GF, Buckner RL, Calhoun V, Canales-Rodríguez EJ, Cannon DM, Caseras X, Castellanos FX, Cervenka S, Chaim-Avancini TM, Ching CRK, Chubar V, Clark VP, Conrod P, Conzelmann A, Crespo-Facorro B, Crivello F, Crone EA, Dale AM, Dannlowski U, Davey C, de Geus EJC, de Haan L, de Zubicaray GI, den Braber A, Dickie EW, Di Giorgio A, Doan NT, Dørum ES, Ehrlich S, Erk S, Espeseth T, Fatouros-Bergman H, Fisher SE, Fouche JP, Franke B, Frodl T, Fuentes-Claramonte P, Glahn DC, Gotlib IH, Grabe HJ, Grimm O, Groenewold NA, Grotegerd D, Gruber O, Gruner P, Gur RE, Gur RC, Hahn T, Harrison BJ, Hartman CA, Hatton SN, Heinz A, Heslenfeld DJ, Hibar DP, Hickie IB, Ho BC, Hoekstra PJ, Hohmann S, Holmes AJ, Hoogman M, Hosten N, Howells FM, Hulshoff Pol HE, Huyser C, Jahanshad N, James A, Jernigan TL, Jiang J, Jönsson EG, Joska J… See abstract for full author list ➔ Frangou S, et al. Hum Brain Mapp. 2022 Jan;43(1):431-451. doi: 10.1002/hbm.25364. Epub 2021 Feb 17. Hum Brain Mapp. 2022. PMID: 33595143 Free PMC article.
Previous research has shown that robust estimates of the association between age and brain morphometry require large-scale studies. In response, we used cross-sectional data from 17,075 individuals aged 3-90 years from the Enhancing Neuroimaging Genetics through Meta-Analy …
Previous research has shown that robust estimates of the association between age and brain morphometry require large-scale studies. I …
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.
Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, Almasy L, Almeida J, Alpert K, Andreasen NC, Andreassen OA, Apostolova LG, Appel K, Armstrong NJ, Aribisala B, Bastin ME, Bauer M, Bearden CE, Bergmann O, Binder EB, Blangero J, Bockholt HJ, Bøen E, Bois C, Boomsma DI, Booth T, Bowman IJ, Bralten J, Brouwer RM, Brunner HG, Brohawn DG, Buckner RL, Buitelaar J, Bulayeva K, Bustillo JR, Calhoun VD, Cannon DM, Cantor RM, Carless MA, Caseras X, Cavalleri GL, Chakravarty MM, Chang KD, Ching CR, Christoforou A, Cichon S, Clark VP, Conrod P, Coppola G, Crespo-Facorro B, Curran JE, Czisch M, Deary IJ, de Geus EJ, den Braber A, Delvecchio G, Depondt C, de Haan L, de Zubicaray GI, Dima D, Dimitrova R, Djurovic S, Dong H, Donohoe G, Duggirala R, Dyer TD, Ehrlich S, Ekman CJ, Elvsåshagen T, Emsell L, Erk S, Espeseth T, Fagerness J, Fears S, Fedko I, Fernández G, Fisher SE, Foroud T, Fox PT, Francks C, Frangou S, Frey EM, Frodl T, Frouin V, Garavan H, Giddaluru S, Glahn DC, Godlewska B, Goldstein RZ, Gollub RL, Grabe HJ, Grimm O, Gruber O, Guadalupe T, Gur RE, Gur RC, Göring HH, Ha… See abstract for full author list ➔ Thompson PM, et al. Brain Imaging Behav. 2014 Jun;8(2):153-82. doi: 10.1007/s11682-013-9269-5. Brain Imaging Behav. 2014. PMID: 24399358 Free PMC article. Review.
By meta-analyzing results from many sites, ENIGMA has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected. ...Working groups also …
By meta-analyzing results from many sites, ENIGMA has detected factors that affect the brain that no individual site could detect on …
Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia.
Ho BC, Andreasen NC, Ziebell S, Pierson R, Magnotta V. Ho BC, et al. Arch Gen Psychiatry. 2011 Feb;68(2):128-37. doi: 10.1001/archgenpsychiatry.2010.199. Arch Gen Psychiatry. 2011. PMID: 21300943 Free PMC article.
CONTEXT: Progressive brain volume changes in schizophrenia are thought to be due principally to the disease. ...OBJECTIVE: To evaluate relative contributions of 4 potential predictors (illness duration, antipsychotic treatment, illness severity, and substance abuse) of …
CONTEXT: Progressive brain volume changes in schizophrenia are thought to be due principally to the disease. ...OBJECTIVE: To evaluat …
Association between brain-derived neurotrophic factor Val66Met gene polymorphism and progressive brain volume changes in schizophrenia.
Ho BC, Andreasen NC, Dawson JD, Wassink TH. Ho BC, et al. Am J Psychiatry. 2007 Dec;164(12):1890-9. doi: 10.1176/appi.ajp.2007.05111903. Am J Psychiatry. 2007. PMID: 18056245 Free PMC article.
OBJECTIVE: Factors underlying progressive brain volume changes in schizophrenia remain poorly understood. The authors investigated whether a gene polymorphism influencing neuroplasticity may contribute to longitudinal brain volume alterations. ...Changes in brain …
OBJECTIVE: Factors underlying progressive brain volume changes in schizophrenia remain poorly understood. The authors investigated wh …
Hippocampus volume and treatment delays in first-episode schizophrenia.
Ho BC, Alicata D, Mola C, Andreasen NC. Ho BC, et al. Am J Psychiatry. 2005 Aug;162(8):1527-9. doi: 10.1176/appi.ajp.162.8.1527. Am J Psychiatry. 2005. PMID: 16055776
Previous MRI studies have reported no significant correlations between duration of untreated initial psychosis and brain volumes but have not examined specific brain regions that may be most susceptible to neuronal damage. ...
Previous MRI studies have reported no significant correlations between duration of untreated initial psychosis and brain volumes but …
Cigarette smoking and white matter microstructure in schizophrenia.
Cullen KR, Wallace S, Magnotta VA, Bockholt J, Ehrlich S, Gollub RL, Manoach DS, Ho BC, Clark VP, Lauriello J, Bustillo JR, Schulz SC, Andreasen NC, Calhoun VD, Lim KO, White T. Cullen KR, et al. Psychiatry Res. 2012 Feb 28;201(2):152-8. doi: 10.1016/j.pscychresns.2011.08.010. Epub 2012 Mar 3. Psychiatry Res. 2012. PMID: 22386966 Free PMC article.
Mean FA was calculated in four global regions of interest (ROIs) (whole brain, cerebellum, brainstem, and total cortical) as well as in four regional ROIs (frontal, temporal, parietal and occipital lobes). ...Without IQ correction, significant between-group effects for FA …
Mean FA was calculated in four global regions of interest (ROIs) (whole brain, cerebellum, brainstem, and total cortical) as well as …
Spatial characteristics of white matter abnormalities in schizophrenia.
White T, Ehrlich S, Ho BC, Manoach DS, Caprihan A, Schulz SC, Andreasen NC, Gollub RL, Calhoun VD, Magnotta VA. White T, et al. Schizophr Bull. 2013 Sep;39(5):1077-86. doi: 10.1093/schbul/sbs106. Epub 2012 Sep 16. Schizophr Bull. 2013. PMID: 22987296 Free PMC article.
There is considerable evidence implicating brain white matter (WM) abnormalities in the pathophysiology of schizophrenia; however, the spatial localization of WM abnormalities reported in the existing studies is heterogeneous. ...We measured fractional anisotropy (FA) in …
There is considerable evidence implicating brain white matter (WM) abnormalities in the pathophysiology of schizophrenia; however, th …
37 results