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Early expansion of donor-specific Tregs in tolerant kidney transplant recipients.
Savage TM, Shonts BA, Obradovic A, Dewolf S, Lau S, Zuber J, Simpson MT, Berglund E, Fu J, Yang S, Ho SH, Tang Q, Turka LA, Shen Y, Sykes M. Savage TM, et al. Among authors: Ho SH. JCI Insight. 2018 Nov 15;3(22):e124086. doi: 10.1172/jci.insight.124086. JCI Insight. 2018. PMID: 30429370 Free PMC article.
Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool.
Fu J, Zuber J, Martinez M, Shonts B, Obradovic A, Wang H, Lau SP, Xia A, Waffarn EE, Frangaj K, Savage TM, Simpson MT, Yang S, Guo XV, Miron M, Senda T, Rogers K, Rahman A, Ho SH, Shen Y, Griesemer A, Farber DL, Kato T, Sykes M. Fu J, et al. Among authors: Ho SH. Cell Stem Cell. 2019 Feb 7;24(2):227-239.e8. doi: 10.1016/j.stem.2018.11.007. Epub 2018 Nov 29. Cell Stem Cell. 2019. PMID: 30503142 Free PMC article.
Characterization, biology, and expansion of regulatory T cells in the Cynomolgus macaque for preclinical studies.
Alonso-Guallart P, Zitsman JS, Stern J, Kofman SB, Woodland D, Ho SH, Sondermeijer HP, Bühler L, Griesemer A, Sykes M, Duran-Struuck R. Alonso-Guallart P, et al. Among authors: Ho SH. Am J Transplant. 2019 Aug;19(8):2186-2198. doi: 10.1111/ajt.15313. Epub 2019 Mar 29. Am J Transplant. 2019. PMID: 30768842
Siplizumab selectively depletes effector memory T cells and promotes a relative expansion of alloreactive regulatory T cells in vitro.
Podestà MA, Binder C, Sellberg F, DeWolf S, Shonts B, Ho SH, Obradovic A, Waffarn E, Danzl N, Berglund D, Sykes M. Podestà MA, et al. Among authors: Ho SH. Am J Transplant. 2020 Jan;20(1):88-100. doi: 10.1111/ajt.15533. Epub 2019 Aug 13. Am J Transplant. 2020. PMID: 31319439
Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites.
Kumar BV, Ma W, Miron M, Granot T, Guyer RS, Carpenter DJ, Senda T, Sun X, Ho SH, Lerner H, Friedman AL, Shen Y, Farber DL. Kumar BV, et al. Among authors: Ho SH. Cell Rep. 2017 Sep 19;20(12):2921-2934. doi: 10.1016/j.celrep.2017.08.078. Cell Rep. 2017. PMID: 28930685 Free PMC article.
Dendritic Cells Display Subset and Tissue-Specific Maturation Dynamics over Human Life.
Granot T, Senda T, Carpenter DJ, Matsuoka N, Weiner J, Gordon CL, Miron M, Kumar BV, Griesemer A, Ho SH, Lerner H, Thome JJC, Connors T, Reizis B, Farber DL. Granot T, et al. Among authors: Ho SH. Immunity. 2017 Mar 21;46(3):504-515. doi: 10.1016/j.immuni.2017.02.019. Immunity. 2017. PMID: 28329707 Free PMC article.
GalT-KO pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of hCD47 on porcine blood vessels.
Watanabe H, Sahara H, Nomura S, Tanabe T, Ekanayake-Alper DK, Boyd LK, Louras NJ, Asfour A, Danton MA, Ho SH, Arn SJ, Hawley RJ, Shimizu A, Nagayasu T, Ayares D, Lorber MI, Sykes M, Sachs DH, Yamada K. Watanabe H, et al. Among authors: Ho SH. Xenotransplantation. 2018 Sep;25(5):e12391. doi: 10.1111/xen.12391. Epub 2018 Mar 12. Xenotransplantation. 2018. PMID: 29527745 Free PMC article.
Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop.
Chen X, Deng H, Churchill MJ, Luchsinger LL, Du X, Chu TH, Friedman RA, Middelhoff M, Ding H, Tailor YH, Wang ALE, Liu H, Niu Z, Wang H, Jiang Z, Renders S, Ho SH, Shah SV, Tishchenko P, Chang W, Swayne TC, Munteanu L, Califano A, Takahashi R, Nagar KK, Renz BW, Worthley DL, Westphalen CB, Hayakawa Y, Asfaha S, Borot F, Lin CS, Snoeck HW, Mukherjee S, Wang TC. Chen X, et al. Among authors: Ho SH. Cell Stem Cell. 2017 Dec 7;21(6):747-760.e7. doi: 10.1016/j.stem.2017.11.003. Epub 2017 Nov 30. Cell Stem Cell. 2017. PMID: 29198940 Free PMC article.
A three-dimensional model of human lung development and disease from pluripotent stem cells.
Chen YW, Huang SX, de Carvalho ALRT, Ho SH, Islam MN, Volpi S, Notarangelo LD, Ciancanelli M, Casanova JL, Bhattacharya J, Liang AF, Palermo LM, Porotto M, Moscona A, Snoeck HW. Chen YW, et al. Among authors: Ho SH. Nat Cell Biol. 2017 May;19(5):542-549. doi: 10.1038/ncb3510. Epub 2017 Apr 24. Nat Cell Biol. 2017. PMID: 28436965 Free PMC article.
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