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Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression.
Timmerman LA, Clipstone NA, Ho SN, Northrop JP, Crabtree GR. Timmerman LA, et al. Among authors: ho sn. Nature. 1996 Oct 31;383(6603):837-40. doi: 10.1038/383837a0. Nature. 1996. PMID: 8893011
Functional analysis of Fas signaling in vivo using synthetic inducers of dimerization.
Spencer DM, Belshaw PJ, Chen L, Ho SN, Randazzo F, Crabtree GR, Schreiber SL. Spencer DM, et al. Among authors: ho sn. Curr Biol. 1996 Jul 1;6(7):839-47. doi: 10.1016/s0960-9822(02)00607-3. Curr Biol. 1996. PMID: 8805308
The NFAT-related protein NFATL1 (TonEBP/NFAT5) is induced upon T cell activation in a calcineurin-dependent manner.
Trama J, Lu Q, Hawley RG, Ho SN. Trama J, et al. Among authors: ho sn. J Immunol. 2000 Nov 1;165(9):4884-94. doi: 10.4049/jimmunol.165.9.4884. J Immunol. 2000. PMID: 11046013
Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc.
Wolfe SA, Zhou P, Dötsch V, Chen L, You A, Ho SN, Crabtree GR, Wagner G, Verdine GL. Wolfe SA, et al. Among authors: ho sn. Nature. 1997 Jan 9;385(6612):172-6. doi: 10.1038/385172a0. Nature. 1997. PMID: 8990122
Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction.
Beals CR, Clipstone NA, Ho SN, Crabtree GR. Beals CR, et al. Among authors: ho sn. Genes Dev. 1997 Apr 1;11(7):824-34. doi: 10.1101/gad.11.7.824. Genes Dev. 1997. PMID: 9106655
Redundant expression but selective utilization of nuclear factor of activated T cells family members.
Timmerman LA, Healy JI, Ho SN, Chen L, Goodnow CC, Crabtree GR. Timmerman LA, et al. Among authors: ho sn. J Immunol. 1997 Sep 15;159(6):2735-40. J Immunol. 1997. PMID: 9300694
Dimeric ligands define a role for transcriptional activation domains in reinitiation.
Ho SN, Biggar SR, Spencer DM, Schreiber SL, Crabtree GR. Ho SN, et al. Nature. 1996 Aug 29;382(6594):822-6. doi: 10.1038/382822a0. Nature. 1996. PMID: 8752278
NF-AT components define a family of transcription factors targeted in T-cell activation.
Northrop JP, Ho SN, Chen L, Thomas DJ, Timmerman LA, Nolan GP, Admon A, Crabtree GR. Northrop JP, et al. Among authors: ho sn. Nature. 1994 Jun 9;369(6480):497-502. doi: 10.1038/369497a0. Nature. 1994. PMID: 8202141
Specific inhibition of formation of transcription complexes by a calicheamicin oligosaccharide: a paradigm for the development of transcriptional antagonists.
Ho SN, Boyer SH, Schreiber SL, Danishefsky SJ, Crabtree GR. Ho SN, et al. Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9203-7. doi: 10.1073/pnas.91.20.9203. Proc Natl Acad Sci U S A. 1994. PMID: 7937742 Free PMC article.
NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity.
Ho SN, Thomas DJ, Timmerman LA, Li X, Francke U, Crabtree GR. Ho SN, et al. J Biol Chem. 1995 Aug 25;270(34):19898-907. doi: 10.1074/jbc.270.34.19898. J Biol Chem. 1995. PMID: 7650004
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