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A consensus DNA-binding site for the androgen receptor.
Roche PJ, Hoare SA, Parker MG. Roche PJ, et al. Among authors: hoare sa. Mol Endocrinol. 1992 Dec;6(12):2229-35. doi: 10.1210/mend.6.12.1491700. Mol Endocrinol. 1992. PMID: 1491700
Mutations in the estrogen receptor ligand binding domain discriminate between hormone-dependent transactivation and transrepression.
Valentine JE, Kalkhoven E, White R, Hoare S, Parker MG. Valentine JE, et al. J Biol Chem. 2000 Aug 18;275(33):25322-9. doi: 10.1074/jbc.M002497200. J Biol Chem. 2000. PMID: 10840033
The AF1 and AF2 domains of the androgen receptor interact with distinct regions of SRC1.
Bevan CL, Hoare S, Claessens F, Heery DM, Parker MG. Bevan CL, et al. Mol Cell Biol. 1999 Dec;19(12):8383-92. doi: 10.1128/mcb.19.12.8383. Mol Cell Biol. 1999. PMID: 10567563 Free PMC article.
Molecular determinants of the estrogen receptor-coactivator interface.
Mak HY, Hoare S, Henttu PM, Parker MG. Mak HY, et al. Mol Cell Biol. 1999 May;19(5):3895-903. doi: 10.1128/mcb.19.5.3895. Mol Cell Biol. 1999. PMID: 10207113 Free PMC article.
Estrogen receptors alpha and beta form heterodimers on DNA.
Cowley SM, Hoare S, Mosselman S, Parker MG. Cowley SM, et al. J Biol Chem. 1997 Aug 8;272(32):19858-62. doi: 10.1074/jbc.272.32.19858. J Biol Chem. 1997. PMID: 9242648
A signature motif in transcriptional co-activators mediates binding to nuclear receptors.
Heery DM, Kalkhoven E, Hoare S, Parker MG. Heery DM, et al. Nature. 1997 Jun 12;387(6634):733-6. doi: 10.1038/42750. Nature. 1997. PMID: 9192902
Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization.
Fawell SE, White R, Hoare S, Sydenham M, Page M, Parker MG. Fawell SE, et al. Proc Natl Acad Sci U S A. 1990 Sep;87(17):6883-7. doi: 10.1073/pnas.87.17.6883. Proc Natl Acad Sci U S A. 1990. PMID: 2395882 Free PMC article.
Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.
Cavaill├Ęs V, Dauvois S, L'Horset F, Lopez G, Hoare S, Kushner PJ, Parker MG. Cavaill├Ęs V, et al. EMBO J. 1995 Aug 1;14(15):3741-51. EMBO J. 1995. PMID: 7641693 Free PMC article.
Environmentally persistent alkylphenolic compounds are estrogenic.
White R, Jobling S, Hoare SA, Sumpter JP, Parker MG. White R, et al. Among authors: hoare sa. Endocrinology. 1994 Jul;135(1):175-82. doi: 10.1210/endo.135.1.8013351. Endocrinology. 1994. PMID: 8013351
Sex-hormone-binding globulin and breast cancer risk.
Moore JW, Key TJ, Clark GM, Hoare SA, Allen DS, Wang DY. Moore JW, et al. Among authors: hoare sa. Anticancer Res. 1987 Sep-Oct;7(5B):1039-47. Anticancer Res. 1987. PMID: 3324935 Review.
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