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Synthetic peptide vaccine development: designing dual epitopes into a single pilin peptide immunogen generates antibody cross-reactivity between two strains of Pseudomonas aeruginosa.
Hackbarth C, Hodges RS. Hackbarth C, et al. Chem Biol Drug Des. 2010 Oct;76(4):293-304. doi: 10.1111/j.1747-0285.2010.01021.x. Epub 2010 Aug 30. Chem Biol Drug Des. 2010. PMID: 20807222 Free PMC article.
Synthetic peptide vaccine development: measurement of polyclonal antibody affinity and cross-reactivity using a new peptide capture and release system for surface plasmon resonance spectroscopy.
Cachia PJ, Kao DJ, Hodges RS. Cachia PJ, et al. J Mol Recognit. 2004 Nov-Dec;17(6):540-57. doi: 10.1002/jmr.682. J Mol Recognit. 2004. PMID: 15386623
Rational design of α-helical antimicrobial peptides to target Gram-negative pathogens, Acinetobacter baumannii and Pseudomonas aeruginosa: utilization of charge, 'specificity determinants,' total hydrophobicity, hydrophobe type and location as design parameters to improve the therapeutic ratio.
Jiang Z, Vasil AI, Gera L, Vasil ML, Hodges RS. Jiang Z, et al. Chem Biol Drug Des. 2011 Apr;77(4):225-40. doi: 10.1111/j.1747-0285.2011.01086.x. Epub 2011 Feb 2. Chem Biol Drug Des. 2011. PMID: 21219588 Free PMC article.
Platform technology to generate broadly cross-reactive antibodies to α-helical epitopes in hemagglutinin proteins from influenza A viruses.
Jiang Z, Gera L, Mant CT, Hirsch B, Yan Z, Shortt JA, Pollock DD, Qian Z, Holmes KV, Hodges RS. Jiang Z, et al. Among authors: hodges rs. Biopolymers. 2016 Mar;106(2):144-159. doi: 10.1002/bip.22808. Biopolymers. 2016. PMID: 26799790 Free PMC article.
"Specificity Determinants" Improve Therapeutic Indices of Two Antimicrobial Peptides Piscidin 1 and Dermaseptin S4 Against the Gram-negative Pathogens Acinetobacter baumannii and Pseudomonas aeruginosa.
Jiang Z, Vasil AI, Vasil ML, Hodges RS. Jiang Z, et al. Among authors: hodges rs. Pharmaceuticals (Basel). 2014 Mar 25;7(4):366-91. doi: 10.3390/ph7040366. Pharmaceuticals (Basel). 2014. PMID: 24670666 Free PMC article.
Role of positively charged residues on the polar and non-polar faces of amphipathic α-helical antimicrobial peptides on specificity and selectivity for Gram-negative pathogens.
Jiang Z, Mant CT, Vasil M, Hodges RS. Jiang Z, et al. Among authors: hodges rs. Chem Biol Drug Des. 2018 Jan;91(1):75-92. doi: 10.1111/cbdd.13058. Epub 2017 Jul 14. Chem Biol Drug Des. 2018. PMID: 28636788
NMR solution structure of a highly stable de novo heterodimeric coiled-coil.
Lindhout DA, Litowski JR, Mercier P, Hodges RS, Sykes BD. Lindhout DA, et al. Biopolymers. 2004 Dec 5;75(5):367-75. doi: 10.1002/bip.20150. Biopolymers. 2004. PMID: 15457434
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