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Chemokine-dependent B cell-T cell interactions in chronic lymphocytic leukemia and multiple myeloma - targets for therapeutic intervention?

Jöhrer K, Hofbauer SW, Zelle-Rieser C, Greil R, Hartmann TN. Jöhrer K, et al. Among authors: hofbauer sw. Expert Opin Biol Ther. 2012 Apr;12(4):425-41. doi: 10.1517/14712598.2012.664128. Epub 2012 Feb 15. Expert Opin Biol Ther. 2012. PMID: 22332909 Review.

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PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia.

Holler C, Piñón JD, Denk U, Heyder C, Hofbauer S, Greil R, Egle A. Holler C, et al. Blood. 2009 Mar 19;113(12):2791-4. doi: 10.1182/blood-2008-06-160713. Epub 2009 Jan 23. Blood. 2009. PMID: 19168795 Free article.

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MDM2 SNP309 is associated with poor outcome in B-cell chronic lymphocytic leukemia.

Gryshchenko I, Hofbauer S, Stoecher M, Daniel PT, Steurer M, Gaiger A, Eigenberger K, Greil R, Tinhofer I. Gryshchenko I, et al. J Clin Oncol. 2008 May 10;26(14):2252-7. doi: 10.1200/JCO.2007.11.5212. J Clin Oncol. 2008. PMID: 18467716

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The AKT1 isoform plays a dominant role in the survival and chemoresistance of chronic lymphocytic leukaemia cells.

Hofbauer SW, Krenn PW, Piñόn Hofbauer J, Pucher S, Asslaber D, Egle A, Hartmann TN, Greil R. Hofbauer SW, et al. Br J Haematol. 2016 Mar;172(5):815-9. doi: 10.1111/bjh.13542. Epub 2015 Jul 6. Br J Haematol. 2016. PMID: 26147087 Free PMC article. No abstract available.

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ILK Induction in Lymphoid Organs by a TNFα-NF-κB-Regulated Pathway Promotes the Development of Chronic Lymphocytic Leukemia.

Krenn PW, Hofbauer SW, Pucher S, Hutterer E, Hinterseer E, Denk U, Asslaber D, Ganghammer S, Sternberg C, Neureiter D, Aberger F, Wickström SA, Egle A, Greil R, Hartmann TN. Krenn PW, et al. Among authors: hofbauer sw. Cancer Res. 2016 Apr 15;76(8):2186-96. doi: 10.1158/0008-5472.CAN-15-3379. Epub 2016 Feb 2. Cancer Res. 2016. PMID: 26837762

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Tiam1/Rac1 signals contribute to the proliferation and chemoresistance, but not motility, of chronic lymphocytic leukemia cells.

Hofbauer SW, Krenn PW, Ganghammer S, Asslaber D, Pichler U, Oberascher K, Henschler R, Wallner M, Kerschbaum H, Greil R, Hartmann TN. Hofbauer SW, et al. Blood. 2014 Apr 3;123(14):2181-8. doi: 10.1182/blood-2013-08-523563. Epub 2014 Feb 5. Blood. 2014. PMID: 24501217 Free article.

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Modifying akt signaling in B-cell chronic lymphocytic leukemia cells.

Hofbauer SW, Piñón JD, Brachtl G, Haginger L, Wang W, Jöhrer K, Tinhofer I, Hartmann TN, Greil R. Hofbauer SW, et al. Cancer Res. 2010 Sep 15;70(18):7336-44. doi: 10.1158/0008-5472.CAN-09-4411. Epub 2010 Sep 7. Cancer Res. 2010. PMID: 20823161

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Differential bone marrow homing capacity of VLA-4 and CD38 high expressing chronic lymphocytic leukemia cells.

Brachtl G, Sahakyan K, Denk U, Girbl T, Alinger B, Hofbauer SW, Neureiter D, Hofbauer JP, Egle A, Greil R, Hartmann TN. Brachtl G, et al. Among authors: hofbauer sw. PLoS One. 2011;6(8):e23758. doi: 10.1371/journal.pone.0023758. Epub 2011 Aug 18. PLoS One. 2011. PMID: 21876768 Free PMC article.

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Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.

Desch P, Asslaber D, Kern D, Schnidar H, Mangelberger D, Alinger B, Stoecher M, Hofbauer SW, Neureiter D, Tinhofer I, Aberger F, Hartmann TN, Greil R. Desch P, et al. Among authors: hofbauer sw. Oncogene. 2010 Sep 2;29(35):4885-95. doi: 10.1038/onc.2010.243. Epub 2010 Jul 5. Oncogene. 2010. PMID: 20603613

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Hedgehog/GLI and PI3K signaling in the initiation and maintenance of chronic lymphocytic leukemia.

Kern D, Regl G, Hofbauer SW, Altenhofer P, Achatz G, Dlugosz A, Schnidar H, Greil R, Hartmann TN, Aberger F. Kern D, et al. Among authors: hofbauer sw. Oncogene. 2015 Oct 16;34(42):5341-51. doi: 10.1038/onc.2014.450. Epub 2015 Feb 2. Oncogene. 2015. PMID: 25639866 Free PMC article.

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